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Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: tDCS + language therapy Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia

NCT04486586
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional Results available

Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment

NCT02901574
View directory record Official record
Conditions
Stroke
Interventions
Anodal or Cathodal tDCS, Sham, Computerized naming therapy
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional Results available

Combining tDCS and CILT in Non-fluent Aphasia

NCT05561400
View directory record Official record
Conditions
Aphasia, Non-fluent Aphasia, Stroke, Brain Injuries
Interventions
tDCS, Placebo
Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Duluth, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 13, 2026, 3:26 PM EDT
Active, not recruiting Not applicable Interventional

HD-tDCS for Phonological Impairment in Aphasia

NCT06010030
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Targeted Transcranial Direct Current Stimulation, Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 13, 2026, 3:26 PM EDT
Recruiting Not applicable Interventional

Remotely-supervised Neuromodulation in PPA

NCT07260253
View directory record Official record
Conditions
Primary Progressive Aphasia(PPA), Progressive Aphasia, Progressive Aphasia in Alzheimer's Disease, Logopenic Progressive Aphasia (LPA), Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA)
Interventions
Lexical Retrieval Cascade Treatment, Remotely Supervised Transcranial Direct Current Stimulation- Active, Remotely Supervised Transcranial Direct Current Stimulation - Sham
Behavioral · Device
Lead sponsor
Maya Henry
Other
Eligibility
40 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
San Francisco, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 13, 2026, 3:26 PM EDT
Recruiting Not applicable Interventional

Enhancing Language Function in Primary Progressive Aphasia

NCT04920318
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
tDCS + language therapy, sham TDCS + language therapy
Combination Product
Lead sponsor
University of Arizona
Other
Eligibility
45 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 13, 2026, 3:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

NCT04142866
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation, Speech-Language Therapy (SLT)
Device · Behavioral
Lead sponsor
City University of New York
Other
Eligibility
21 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Sep 13, 2026, 3:26 PM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation for Post-Stroke Aphasia

NCT02461355
View directory record Official record
Conditions
Stroke
Interventions
Aphasia therapy, Anodal tDCS, Sham tDCS
Behavioral · Device
Lead sponsor
Columbia University
Other
Eligibility
21 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Maywood, New Jersey
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Sep 13, 2026, 3:26 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

NCT05386394
View directory record Official record
Conditions
Primary Progressive Aphasia, Logopenic Progressive Aphasia, Non-Fluent Primary Progressive Aphasia
Interventions
Active tDCS + Language Therapy, Sham tDCS + Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 13, 2026, 3:26 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia

NCT05901233
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Remotely supervised Transcranial Direct Current Stimulation (RS-tDCS), Remotely supervised sham tDCS (RS-sham-tDCS), Lexical Retrieval Training (LRT), Video Implemented Script Training in Aphasia (VISTA)
Device · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
San Francisco, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 13, 2026, 3:26 PM EDT
Completed No phase listed Observational

Transcranial Direct Current Stimulation and Autism

NCT01603225
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
14 Years to 79 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Sep 13, 2026, 3:26 PM EDT
Recruiting Not applicable Interventional

Neurostimulation for the Treatment of Post-Stroke Aphasia

NCT05194566
View directory record Official record
Conditions
Post-stroke Aphasia
Interventions
tACS
Device
Lead sponsor
QVITI S.A.
Industry
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional Results available

Rehabilitating and Decelerating Language Loss in Primary Progressive Aphasia With tDCS Plus Language Therapy

NCT03728582
View directory record Official record
Conditions
Primary Progressive Aphasia, PPA
Interventions
Active tDCS plus Speech-Language Therapy, Sham tDCS plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional

Clinical Feasibility of Transcranial Direct Current Stimulation [tDCS] With Standard Aphasia Therapy

NCT03272906
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation, Speech-language therapy
Device · Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation for Primary Progressive Aphasia

NCT02928848
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Sep 13, 2026, 3:26 PM EDT
Recruiting Not applicable Interventional

Cerebellar Stimulation for Aphasia Rehabilitation

NCT05093673
View directory record Official record
Conditions
Stroke
Interventions
Cathodal Cerebellar tDCS, Semantic Feature Analysis (SFA), Sham
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional Results available

Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia

NCT01709383
View directory record Official record
Conditions
Aphasia
Interventions
Transcranial Direct Current Stimulation, Sham Stimulation
Device
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional Results available

Treating Primary Progressive Aphasia (PPA) Using tDCS

NCT04566731
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham tDCS, Modified Contraint-Induced Language Therapy (mCILT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 13, 2026, 3:26 PM EDT
Recruiting Not applicable Interventional

Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

NCT04432883
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Active Comparator: Experimental: Active cathodal tDCS + language training, Sham Comparator: Placebo cathodal tDCS + Speech and language
Device · Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
25 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Phase 1 Interventional

Transcranial Direct Current Stimulation and Aphasia Language Therapy

NCT01486654
View directory record Official record
Conditions
Nonfluent Aphasia, Stroke
Interventions
Transcranial Direct Current Stimulation - Cathodal stimulation, Transcranial Direct Current Stimulation - Anodal stimulation, Transcranial Direct Current Stimulation - Sham stimulation
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Phase 2 Interventional

Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS

NCT04046991
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
high-definition transcranial direct current stimulation, modified constraint-induced language therapy
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Brain Stimulation on Higher-Order Cognition

NCT03814967
View directory record Official record
Conditions
Schizophrenia
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 50 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 13, 2026, 3:26 PM EDT
Completed Not applicable Interventional Results available

Improving Aphasia Using Electrical Brain Stimulation

NCT04963803
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Active transcranial direct current stimulation (tDCS), Sham transcranial direct current stimulation (tDCS), Language Specific Attention Treatment
Device · Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 13, 2026, 3:26 PM EDT
Withdrawn Not applicable Interventional

tDCS to Treat Subacute Aphasia

NCT04048668
View directory record Official record
Conditions
Aphasia, Stroke, Acute
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Sep 13, 2026, 3:26 PM EDT