- Conditions
- Survivor of Childhood Cancer, Insomnia, Acute Lymphoblastic Leukemia (ALL)
- Interventions
- Soterix tVNS device, Soterix tVNS device (sham programmed), Sleep Quality, Neurocognitive and mental health outcomes
- Device · Behavioral
- Lead sponsor
- St. Jude Children's Research Hospital
- Other
- Eligibility
- 20 Years to 50 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
Search Results
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Showing 1–24
of 45
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Cerebral, Transcutaneous Vagal Nerve Stimulation (tVNS), Endovascular Treatment
- Interventions
- Transcutaneous Vagal Nerve Stimulation
- Device
- Lead sponsor
- Marshall Holland
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Cognitive Performance
- Interventions
- Transcutaneous Vagal Nerve Stimulation (tVNS)
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Stroke
- Interventions
- Unilateral Left tVNS stimulation, Bilateral tVNS stimulation, Unilateral Left Sham stimulation, Bilateral Sham stimulation, Unilateral Right tVNS stimulation, Unilateral Right Sham stimulation
- Procedure
- Lead sponsor
- Georgia Institute of Technology
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Juvenile Idiopathic Arthritis (JIA)
- Interventions
- Active tcVNS, Sham tcVNS
- Device
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 5 Years to 18 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 7
- States / cities
- San Francisco, California • Orlando, Florida • Indianapolis, Indiana + 4 more
- Conditions
- Chronic Dizziness, Persistent Postural Perceptual Dizziness
- Interventions
- Sham Device, Auricular transcutaneous vagus nerve stimulation
- Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Self Harm, Suicidal Ideation
- Interventions
- tVNS Program, Phone App Program, tVNS and Phone App Program, Sham tNVS and Control App
- Device · Other · Combination Product
- Lead sponsor
- University of Notre Dame
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 2
- States / cities
- South Bend, Indiana • Rochester, New York
- Conditions
- Healthy Young Adults
- Interventions
- tVNS, Motor training
- Other
- Lead sponsor
- Georgia Institute of Technology
- Other
- Eligibility
- 18 Years to 39 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Post-acute COVID-19 Syndrome, Postural Tachycardia Syndrome (POTS), Long COVID, SARS CoV 2 Infection
- Interventions
- Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls, Levels of inflammatory cytokine ( IL-6) in controls, Effect on inflammation after chronic PNS stimulation
- Diagnostic Test
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Major Depressive Disorder
- Interventions
- Active transcutaneous vagus nerve stimulation, Sham transcutaneous vagus nerve stimulation
- Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 24 Years to 45 Years · Female only
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Charlestown, Massachusetts
- Conditions
- Stress Disorders, Post-Traumatic
- Interventions
- Microneurography, Combat virtual reality video clip, Handgrip Exercise, Cold Pressor Test (CPT), Sodium Nitroprusside (SNP), Phenylephrine, Losartan, Atenolol, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham Transcutaneous Vagal Nerve Stimulation (tVNS)
- Procedure · Behavioral · Drug + 1 more
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 134 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2027
- U.S. locations
- 1
- States / cities
- Decatur, Georgia
- Conditions
- Vagus Nerve Stimulation
- Interventions
- Transcutaneous vagal nerve stimulation
- Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 39 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Knee Osteoarthritis, Central Pain Syndrome
- Interventions
- Transcutaneous vagus nerve stimulation
- Device
- Lead sponsor
- University of Texas, El Paso
- Other
- Eligibility
- 45 Years to 90 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- El Paso, Texas
- Conditions
- TBI Traumatic Brain Injury
- Interventions
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Dyspepsia
- Interventions
- Alimetry, tVNS, Gastroduodenal Manometry
- Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Major Depressive Disorder
- Interventions
- exhalatory-gated transcutaneous vagus nerve stimulation (e-RAVANS), Inhalatory-gated transcutaneous vagus nerve stimulation (i-RAVANS)
- Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 25 Years to 40 Years · Female only
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Older Adults
- Interventions
- tVNS stimulation, Sham stimulation
- Procedure
- Lead sponsor
- Georgia Institute of Technology
- Other
- Eligibility
- 65 Years to 84 Years
- Enrollment
- 34 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Major Depressive Disorder
- Interventions
- active tVNS, Sham tVNS
- Device
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 50 Years to 65 Years
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Charlestown, Massachusetts
- Conditions
- Breast Cancer
- Interventions
- Transcutaneous vagus nerve and acupuncture point stimulation
- Device
- Lead sponsor
- The Healing Consciousness Foundation
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Meadowbrook, Pennsylvania
- Conditions
- Post-traumatic Stress Disorder, Prehypertension
- Interventions
- Device-Guided Breathing (DGB), Sham DGB, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham tVNS
- Device
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2027
- U.S. locations
- 1
- States / cities
- Decatur, Georgia
- Conditions
- no Condition, Electroencephalography, Pupil Diameter
- Interventions
- Transdermal Vagus Nerve Stimulation (tVNS)
- Device
- Lead sponsor
- Arkansas Tech University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Russellville, Arkansas
- Conditions
- Low Back Pain
- Interventions
- Stimulation at Location 1, Stimulation at Location 2
- Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Charlestown, Massachusetts
- Conditions
- Nonsuicidal Self Injury, Alcohol Abuse, Vagus Nerve Stimulation
- Interventions
- Non-invasive Transcutaneous Nerve Stimulation (tVNS), No Intervention
- Device
- Lead sponsor
- University of Notre Dame
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- South Bend, Indiana
- Conditions
- Atrial Fibrillation
- Interventions
- active tVNS, sham tVNS
- Device
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Oklahoma City, Oklahoma