Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 20, 2026, 12:24 AM EDT

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Showing 1–24 of 99 matching trials from the live ClinicalTrials.gov search.
Conditions
Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance
Interventions
AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation, Audiovisual Entrainment, Vibroacoustic Stimulation, Breathwork-Based Auditory Driving Entropy Module (BADEM), Transcranial Electrical Stimulation
Behavioral · Device
Lead sponsor
Tactical Mind Research Coalition, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Transauricular Vagus Nerve Stimulation in Children

NCT06168071
Conditions
Hypoxia-Ischemia, Brain
Interventions
taVNS
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
7 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Healthy
Interventions
Transcutaneous Auricular Vagus Nerve Stimulation, Sham Procedure (No Stimulation)
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Recruiting Not applicable Interventional

taVNS for FRNS in Children

NCT05588063
Conditions
Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
Interventions
Transcutaneous auricular vagus nerve stimulation, Sham device
Device
Lead sponsor
Northwell Health
Other
Eligibility
3 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
New Hyde Park, New York • Philadelphia, Pennsylvania
Conditions
Pain, Chronic, Irritable Bowel Syndrome, Symptom Cluster
Interventions
Home-based taVNS intervention
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 29 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting Not applicable Interventional

taVNS + CCT for Neurocognitive Rehab

NCT07517237
Conditions
Psychosocial Well-being, Neurocognitive Function, Cognitive Complaint, Cognitive Dysfunction
Interventions
taVNS, Computerized Cognitive Training
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
45 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charleston, South Carolina
Suspended Not applicable Interventional Accepts healthy volunteers

taVNS for Letter Learning in Dyslexia

NCT06127550
Conditions
Dyslexia
Interventions
active taVNS, sham taVNS
Device
Lead sponsor
University of Florida
Other
Eligibility
10 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Perinatal Brain Injury
Interventions
Constraint-Induced Movement Therapy (CIMT), Transcutaneous auricular vagus nerve stimulation (taVNS)
Behavioral · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
8 Months to 24 Months
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Cerebral Palsy
Interventions
Custom EMG triggered Soterix taVNS stimulation with CIMT therapy in lab, Custom EMG triggered Soterix taVNS stimulation with CIMT therapy in home
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Months to 18 Months
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
TBI Traumatic Brain Injury
Interventions
Transcutaneous Vagus Nerve Stimulation (tVNS)
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Hemiplegia, Perinatal Brain Injury
Interventions
sTMS, taVNS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
8 Months to 24 Months
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Breast Cancer, Insomnia
Interventions
transauricular Vagus Nerve Stimulation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Non-Invasive Bioelectronic Analytics

NCT04100486
Conditions
Autonomic Dysfunction, Autonomic Imbalance, Autonomic Nervous System Diseases, Vagus Nerve Autonomic Disorder
Interventions
Standing-Squatting-Standing Test, Deep Breathing Test, Cold Pressor Test, Cold Face Test, Valsalva Maneuver, Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
Other · Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Manhasset, New York
Completed Not applicable Interventional Accepts healthy volunteers

taVNS on Pupillary Response and Perceptual Learning

NCT05386563
Conditions
Pupillary Response
Interventions
Transcutaneous Auricular Vagal Nerve Stimulation (taVNS), Sham Stimulation
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional

TaVNS for Delirium

NCT07258082
Conditions
Delirium Treatment, Delirium
Interventions
Transauricular Vagus Nerve Stimulation
Device
Lead sponsor
Stony Brook University
Other
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Stony Brook, New York
Conditions
Anorexia Nervosa
Interventions
taVNS, Sham
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
14 Years to 22 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Breast Cancer Survivors
Interventions
Active taVNS, Sham taVNS
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 79 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Completed Early Phase 1 Interventional Results available

NAC +taVNS in IDM Who Are Poor Oral Feeders

NCT04632069
Conditions
Infant of Diabetic Mother, Oxidative Stress, Vagus Nerve Stimulation, Feeding Disorders
Interventions
N acetyl cysteine + vagus nerve stimulation
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
3 Weeks to 5 Months
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Vagus Nerve Stimulation
Interventions
Active taVNS, Sham taVNS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Duluth, Minnesota
Completed Not applicable Interventional Results available

At-Home taVNS - Stroke Rehab

NCT06616831
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic
Interventions
Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Presbycusis
Interventions
transcutaneous auricular vagus nerve stimulation, Sham Control
Device
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Stimulating Your Nervous System for Calm (SYNC) Study

NCT07871279
Conditions
No Condition
Interventions
taVNS, Mindfulness Meditation, low intensity taVNS
Device · Behavioral · Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 29 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Rosacea, Rosacea, Erythematotelangiectatic, Flushing
Interventions
Transaricular vagus nerve stimulation (taVNS)
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Early Phase 1 Interventional Results available

taVNS Paired With Bottle Feeding in Infants Failing Oral Feeds

NCT04643808
Conditions
Poor Feeding, Infant Development, Vagus Nerve Stimulation
Interventions
transcutaneous auricular vagus nerve stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
3 Weeks to 5 Months
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina