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ClinicalTrials.gov public records Last synced Oct 2, 2026, 7:00 AM EDT

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Showing 25–48 of 122 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: text messaging for smoking cessation Clear all
Recruiting Phase 4 Interventional

Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

NCT06598397
View directory record Official record
Conditions
Human Immunodeficiency Virus (HIV), Smoking Cessation
Interventions
Motivational Interviewing (MI) Counseling, Peer Mentoring, Skills-based Text Messaging, Combination NRT
Behavioral · Drug
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Text Messaging to Improve Adherence to Web-Based Cessation Treatment

NCT02585206
View directory record Official record
Conditions
Smoking Cessation
Interventions
Personalization, Integration, Dynamic Tailoring, Message Intensity, Optimal-Adherence Text
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
1,485 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 2, 2026, 7:00 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

BE Smokefree: Behavioral Economics Incentives to Engage Adolescents in Smoking Cessation

NCT03670264
View directory record Official record
Conditions
Smoking Cessation
Interventions
Quitline Incentive, Tobacco Cessation Incentive, Way to Health (WTH) Platform, Quitline Delivered Treatment
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
14 Years to 21 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Oct 2, 2026, 7:00 AM EDT
Recruiting Phase 3 Interventional

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

NCT05008848
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Smoking Cessation Intervention, Health Promotion and Education, Informational Intervention, Questionnaire Administration
Behavioral · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
223
States / cities
Kingman, Arizona • Fort Smith, Arkansas • St. Helena, California + 186 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Improving Quitline Support Study

NCT03538938
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
1-Call Quitline Counseling, 4-Call Quitline Counseling, Nicotine patch, Nicotine Patch and Nicotine Lozenge, SmokefreeTXT, No SmokefreeTXT, Financial Incentives for Treatment Engagement, No Financial Incentives for Treatment Engagement
Behavioral · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1,316 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Brief Tobacco Intervention in the US Military

NCT03196102
View directory record Official record
Conditions
Tobacco Use, Tobacco Smoking, Smoking, Cigar, Smoking, Pipe, Smoking, Hookah, Nicotine Dependence
Interventions
BTI, Cigarette smoking military tailored pamphlet, Standard smoking cessation intervention
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
2,999 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smoking Cessation for Young Adult Pacific Islanders: Motivating Pacifika Against Cigarettes and Tobacco

NCT03238456
View directory record Official record
Conditions
Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Smoking, Smoking Cessation, Smoking, Cigarette
Interventions
Motivating Pacifika Against Cigarettes and Tobacco
Behavioral
Lead sponsor
Claremont Graduate University
Other
Eligibility
18 Years to 30 Years
Enrollment
278 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Claremont, California • Fullerton, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2017 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pager-Assisted Smoking Cessation Treatment

NCT01207310
View directory record Official record
Conditions
Smoking Cessation
Interventions
smoking cessation counseling, Nicotine patch, alphanumeric pager
Behavioral · Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2017 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional

Quit Smoking Text Message Study

NCT06111755
View directory record Official record
Conditions
Smoking Cessation
Interventions
SmokefreeTXT, Smartband
Other · Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Results available

Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness

NCT04367506
View directory record Official record
Conditions
Tobacco Cessation
Interventions
BecomeAnEX, Usual Care
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text Messaging for Smoking Cessation in College Health Clinics

NCT02191033
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Smoking counseling, Text messaging, Nicotine patch
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 24 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Oct 2, 2026, 7:00 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

NCT05660525
View directory record Official record
Conditions
Smoking Cessation, Smoking, Cigarette, Smoking Reduction, Smoking, Smoking, Tobacco, Quitting Smoking
Interventions
4 weeks of Nicotine lozenge, 8 weeks of Nicotine Replacement Therapy Patch, QuitAid, Smokefree TXT, Tobacco Quitline, 4 weeks of Nicotine Replacement Therapy Patch, 8 Weeks Nicotine Lozenge
Drug · Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
768 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 2, 2026, 7:00 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Telephone All Nations Breath of Life

NCT04764175
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone All Nations Breath of Life, Comparison Program
Behavioral
Lead sponsor
Lehigh University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Short Messaging Service Program to Help Quit Smoking During Perioperative Period.

NCT03839043
View directory record Official record
Conditions
Tobacco Use Cessation, Perioperative/Postoperative Complications, Tobacco Smoking
Interventions
Brief behavioral intervention, SMS Program
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2021 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effective Ads for Quitting Smoking

NCT06485479
View directory record Official record
Conditions
Smoking Behaviors
Interventions
Intervention ads, Control ads
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years and older
Enrollment
1,236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Cessation Support for Latino Smokers

NCT03586596
View directory record Official record
Conditions
Smoking Cessation
Interventions
The Decídetext program, Standard Care Control
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
457 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
3
States / cities
Kansas City, Kansas • Hackensack, New Jersey • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Text Messaging-Based Smoking Cessation Program for Homeless Youth

NCT03874585
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Group counseling and nicotine replacement, Group counseling, nicotine replacement, and text messaging support
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 25 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Los Angeles, California • Venice, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2020 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Results available

iQuit Mindfully: Text Messaging for Smoking Cessation

NCT03029819
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Mindfulness-based Addiction Treatment, iQuit Mindfully, Self-Help guide, Nicotine Patch
Behavioral · Drug
Lead sponsor
Georgia State University
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 2, 2026, 7:00 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Low Dose Computed Tomography for Lung Cancer Screening

NCT03084835
View directory record Official record
Conditions
Smoking
Interventions
Usual Care, WEB+TXT, WEB+TXT+TTS
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young Adults

NCT05847673
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Online Smoking Cessation Intervention, Questionnaire Administration, Health Promotion and Education
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 30 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 19, 2024 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Connecting Alaska Native People to Quit Smoking

NCT03645941
View directory record Official record
Conditions
Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Smoking Cessation, Smoking, Cigarette, Smoking, Tobacco, Smoking
Interventions
Facebook Group
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
19 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Oct 2, 2026, 7:00 AM EDT
Recruiting Not applicable Interventional

Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network

NCT06582693
View directory record Official record
Conditions
Smoking, Smoking Cessation, Second Hand Tobacco Smoke
Interventions
Refer2Quit
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
3,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Clinical Trial to Reduce Harm From Tobacco

NCT02328794
View directory record Official record
Conditions
Smoking Cessation
Interventions
E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm, Loss framing incentive arm, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
6,006 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 2, 2026, 7:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation

NCT03068611
View directory record Official record
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Standard Web-based Smoking Cessation, Alcohol-focused Web-Based Smoking Cessation
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 2, 2026, 7:00 AM EDT