Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 18, 2026, 4:16 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 94 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: total knee arthroplasty device Clear all
Completed Not applicable Interventional

Ambulation Versus Standing on Postoperative Day 0

NCT02879188
View directory record Official record
Conditions
Osteoarthritis
Interventions
Physical Therapy, Standing
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment With Iovera° for Total Knee Arthroplasty (TKA) Post-Operative Pain

NCT03327220
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
iovera°
Device
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
22 Years to 79 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Germantown, Tennessee
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Sep 18, 2026, 4:16 AM EDT
Not listed Phase 4 Interventional

Use of Cold and Compression Therapy With Total Knee Replacement Patients

NCT00712816
View directory record Official record
Conditions
Osteoarthritis, Total Knee Arthroplasty
Interventions
Game Ready Injury Treatment System (CoolSystems Inc.), Ice with compressive bandages
Device · Other
Lead sponsor
CoolSystems, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
10
States / cities
San Diego, California • Honolulu, Hawaii • Winfield, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2012 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional

Collaborative-care Intervention to Promote Physical Activity After Total Knee Arthroplasty

NCT02075931
View directory record Official record
Conditions
Osteoarthritis
Interventions
Physical activity feedback with group meetings, Control
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Sep 18, 2026, 4:16 AM EDT
Withdrawn Not applicable Interventional

Utilization of a Knee Brace With Extension Swing

NCT05179044
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Guardian Sport Rehabilitator knee brace
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.

NCT02127281
View directory record Official record
Conditions
Prosthesis-related Infections, Wound Complications, Joint Diseases, Musculoskeletal Diseases
Interventions
Prevena
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2018 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Results available

Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty

NCT03285542
View directory record Official record
Conditions
Wound Heal
Interventions
DERMABOND, Staples
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Sep 18, 2026, 4:16 AM EDT
Recruiting Not applicable Interventional

Sleep TO Prevent Post-surgical Pain

NCT06976138
View directory record Official record
Conditions
Knee Osteoarthristis
Interventions
Cognitive-Behavioral Therapy for Insomnia, Bright Light therapy via the Re-Timer®, Negative Ion exposure via IonMi Device, Sleep / Knee Osteoarthritis Education
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Baltimore, Maryland • Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 18, 2026, 4:16 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Acupuncture for Pain Management After Hip or Knee Arthroplasty

NCT00455182
View directory record Official record
Conditions
Pain, Postoperative Complications
Interventions
Acupuncture, Sham Acupuncture, Standard medical care
Procedure
Lead sponsor
HealthEast Care System
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Woodbury, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 18, 2015 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Evaluate the Safety and Efficacy of the Saline-coupled Bipolar Sealer in Primary Unilateral Total Knee Arthroplasty

NCT03952546
View directory record Official record
Conditions
Surgical Blood Loss
Interventions
Saline-coupled Bipolar Sealer, Unipolar electrocautery
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Syosset, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Sep 18, 2026, 4:16 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Conventional Instrumentation, Computer Navigation, and Robotic Assistance Techniques in TKA

NCT05629715
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
ROSA Knee System, KneeAlign Computer Assisted Navigation System
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Results available

Orthosensor vs Conventional Total Knee Arthroplasty

NCT03628378
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Verasense
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Bronxville, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Results available

Adductor Canal Catheter Effectiveness and Safety Study

NCT04639128
View directory record Official record
Conditions
Total Knee Replacement Surgery
Interventions
Adductor Canal Catheter
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Leandro, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Sep 18, 2026, 4:16 AM EDT
Terminated Not applicable Interventional Results available

Efficacy of AposTherapy® in Knee OA

NCT03153956
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Calibrated AposTherapy®, Non-Calibrated Sham Apos Therapy Device
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
45 Years to 75 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Sep 18, 2026, 4:16 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Gait and Functional Improvement in Total Knee Arthroplasty With the Use of Verasense for Soft Tissue Balancing

NCT02290119
View directory record Official record
Conditions
Osteoarthritis
Interventions
Sensor-assisted TKR (Verasense), Control - Without the use of Verasense
Device · Procedure
Lead sponsor
Orthosensor, Inc.
Industry
Eligibility
45 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Phase 4 Interventional Results available

Pilot Study Evaluating Alterations in Thrombogenicity and Platelet Reactivity Following Lower Extremity Arthroplasty

NCT01809054
View directory record Official record
Conditions
Primary Total Hip and Knee Arthroplasty
Interventions
Arixtra, Pneumatic compression stockings, Aspirin
Drug · Device
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Sep 18, 2026, 4:16 AM EDT
Recruiting Not applicable Interventional

Biomechanical Footwear as a Non-invasive Alternative and Supplement to Total Knee Replacement

NCT04732962
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
AposHealth, Total Knee Replacement (TKR)
Device · Procedure
Lead sponsor
Geisinger Clinic
Other
Eligibility
45 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Danville, Pennsylvania • Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 18, 2026, 4:16 AM EDT
Completed No phase listed Observational

Multicenter Registry for Effectiveness Analysis of ActiveCare+S.F.T® Mobile Compression Device for Thrombosis Prevention in Hip and Knee Arthroplasty

NCT01984190
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
Not listed
Lead sponsor
Medical Compression Systems
Industry
Eligibility
18 Years and older
Enrollment
411 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
10
States / cities
Little Rock, Alaska • La Jolla, California • Menlo Park, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Results available

Controlled Study of Kneehab XP for Patients Undergoing Total Knee Replacement

NCT01548040
View directory record Official record
Conditions
Total Knee Replacement
Interventions
Kneehab XP, Quadriceps TENS
Device
Lead sponsor
Theragen Inc.
Industry
Eligibility
40 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Results available

Use of Interferential Current (IFC) Therapy After Total Knee Arthroplasty

NCT04137731
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Interferential Current Therapy
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Sep 18, 2026, 4:16 AM EDT
Withdrawn Phase 4 Interventional

ZIPS Study - Zip Incision Approximation vs. STAPLE

NCT02255877
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
Zip Surgical Skin Closure, Steel Staples
Device
Lead sponsor
ZipLine Medical Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 23, 2016 · Synced Sep 18, 2026, 4:16 AM EDT
Not yet recruiting Not applicable Interventional

Using a Smart Implantable Device to Compare Early Recovery in Two Different Knee Arthroplasty Approaches

NCT07348835
View directory record Official record
Conditions
Total Knee Anthroplasty
Interventions
Total Knee Arthroplasty Medial Parapatellar Approach, Total Knee Arthroplasty Subvastus Approach
Procedure
Lead sponsor
Total Joint Specialists
Network
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sandy Springs, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 18, 2026, 4:16 AM EDT
Completed Not applicable Interventional Results available

Pilot Study of PEMF Therapy in Treatment of Post-operative Pain Following Total Knee Arthroplasty

NCT02211534
View directory record Official record
Conditions
Post-Operative Pain Following Total Knee Arthroplasty
Interventions
Pulsed Electromagnetic Field Device (Provant), Sham Pulsed Electromagnetic Field Device
Device
Lead sponsor
Regenesis Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
14
States / cities
Birmingham, Alabama • Phoenix, Arizona • El Cajon, California + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Sep 18, 2026, 4:16 AM EDT
Completed No phase listed Observational

Antero-Posterior Knee Stability

NCT03387839
View directory record Official record
Conditions
Osteoarthritis, Total Knee Arthroplasty, Stability, Knee Osteoarthritis
Interventions
Stress X-Ray
Other
Lead sponsor
David F. Scott, MD
Other
Eligibility
21 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jan 1, 2018 · Synced Sep 18, 2026, 4:16 AM EDT