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ClinicalTrials.gov public records Last synced Oct 9, 2026, 4:04 AM EDT

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Showing 73–96 of 97 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: transcranial direct current stimulation and electrical stimulator Clear all
Recruiting Not applicable Interventional

Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation

NCT04869059
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Transcranial direct current stimulation, sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 75 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 9, 2026, 4:04 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia

NCT04486586
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuromodulation of Cognition in Older Adults

NCT02137122
View directory record Official record
Conditions
Healthy
Interventions
Sham Stimulation, Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 90 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Oct 9, 2026, 4:04 AM EDT
Terminated Not applicable Interventional

Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease

NCT05978804
View directory record Official record
Conditions
Mild Cognitive Impairment, Primary Progressive Aphasia, Dementia
Interventions
Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC
Other · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 9, 2026, 4:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation

NCT03143894
View directory record Official record
Conditions
Breast Cancer, Cognitive Dysfunction, Fatigue
Interventions
tDCS, Sham tDCS
Device · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Oct 9, 2026, 4:04 AM EDT
Terminated Phase 1Phase 2 Interventional

Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression

NCT03999736
View directory record Official record
Conditions
Major Depressive Disorder, Anxiety
Interventions
transcranial direct current stimulation using a Soterix mini-CT device
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 28 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2021 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional

Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression

NCT04948944
View directory record Official record
Conditions
Depression, Anxiety and Fear
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 9, 2026, 4:04 AM EDT
Recruiting Phase 2 Interventional

tDCS for Post-Stroke Cognitive Impairment

NCT06516588
View directory record Official record
Conditions
Stroke, Mild Cognitive Impairment
Interventions
Transcranial Dirrect Current Stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 10, 2024 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Closed-loop System Using Transcranial Direct Current Stimulation (tDCS) for Epilepsy

NCT01415362
View directory record Official record
Conditions
Epilepsy, Seizures
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Cross Frequency tACS on Cognitive Control

NCT03800030
View directory record Official record
Conditions
Cognitive Control, Executive Function
Interventions
Theta-gamma tACS, Delta-beta tACS, Sham tACS
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Oct 9, 2026, 4:04 AM EDT
Active, not recruiting Not applicable Interventional

Treatment Outcomes With tDCS in Post-Stroke Aphasia

NCT03929432
View directory record Official record
Conditions
Aphasia
Interventions
Active Transcranial Direct Current Stimulation with SLT, Sham Transcranial Direct Current Stimulation with SLT
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiological and Functional Mechanisms of Motor Control and Learning

NCT03190590
View directory record Official record
Conditions
Transcranial Direct Current Stimulation
Interventions
tDCS-NeuroConn., TMS - Magstim., Sham tDCS
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Augmenting Cognitive Training In Older Adults

NCT02851511
View directory record Official record
Conditions
Aging
Interventions
Cognitive Training, tDCS (active stimulation), tDCS (sham stimulation), Educational Training
Behavioral · Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
379 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
3
States / cities
Tucson, Arizona • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 9, 2026, 4:04 AM EDT
Recruiting Not applicable Interventional

Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation

NCT05958381
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Transcranial Direct Current Stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Results available

Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury

NCT01795079
View directory record Official record
Conditions
Burn Injury, Chronic Pain, Pruritus, Itching
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Stimulation Study

NCT02067689
View directory record Official record
Conditions
Healthy
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Oct 9, 2026, 4:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury

NCT05762796
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
Interventions
tDCS in Youth with mild traumatic brain injury
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 15 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional

Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)

NCT00521196
View directory record Official record
Conditions
Migraine
Interventions
DC Stimulator (Transcranial Direct Current Stimulator)
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) Augments the Effects of Gamified, Mobile Attention Bias Modification

NCT04348812
View directory record Official record
Conditions
Anxiety, Stress
Interventions
ABMT, Transcranial direct current stimulation
Behavioral · Other
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 45 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2020 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Results available

Nicotine Withdrawal Symptoms and Smoking Relapse

NCT01511614
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Transcranial Direct Current Stimulation, sham, Nicotine patch, Placebo patch, Varenicline Pill, Placebo pill, Motivational Interviewing
Device · Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 31, 2024 · Synced Oct 9, 2026, 4:04 AM EDT
Recruiting Not applicable Interventional

Low Voltage Electrical Stimulation for Depression in Parkinson's Patients

NCT06467695
View directory record Official record
Conditions
Parkinson Disease, Depressive Symptoms
Interventions
BIOPAC Stimsola, BIOPAC Stimsola Sham (zero amps)
Device
Lead sponsor
University of South Alabama
Other
Eligibility
19 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Transcranial Direct Current Stimulation (tDCS) in Chronic Corneal Pain

NCT01575002
View directory record Official record
Conditions
Corneal Pain, Chronic Pain, Neuropathic Pain
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 9, 2026, 4:04 AM EDT
Withdrawn Not applicable Interventional

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

NCT02622945
View directory record Official record
Conditions
Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Oct 9, 2026, 4:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

tDCS Intervention in Primary Progressive Aphasia

NCT02606422
View directory record Official record
Conditions
Primary Progressive Aphasia, MCI, FTD
Interventions
Active HD-tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 9, 2026, 4:04 AM EDT