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ClinicalTrials.gov public records Last synced Sep 30, 2026, 10:58 PM EDT

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Showing 25–48 of 170 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: transcranial direct current stimulation or SHAM Clear all
Terminated Not applicable Interventional

Effectiveness of Transcranial Direct Current Stimulation (tDCS).

NCT04902274
View directory record Official record
Conditions
Ankle Sprains, Musculoskeletal Injury
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation, Physical Therapy
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2022 · Synced Sep 30, 2026, 10:58 PM EDT
Completed Not applicable Interventional Results available

tDCS and Glucose Uptake in Leg Muscles

NCT04016844
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
transcranial direct current stimulation or SHAM
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Sep 30, 2026, 10:58 PM EDT
Recruiting Phase 2 Interventional

Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)

NCT06901687
View directory record Official record
Conditions
Multiple Sclerosis, Depression
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders

NCT07845409
View directory record Official record
Conditions
Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide, Suicidal Ideation, Mental Disorders
Interventions
Soterix 1x1 tES mini-CT
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Transcranial Direct Current Stimulation (tDCS) Coupled With Constraint Induced Movement Therapy in Stroke Patient

NCT01143649
View directory record Official record
Conditions
Stroke, Healthy
Interventions
transcranial direct current stimulation (tDCS), constraint induced movement therapy (CIMT), transcranial alternating current stimulation (tACS)
Device · Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Sep 30, 2026, 10:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Stimulation Paired With Structured Language Learning in Adults

NCT07762118
View directory record Official record
Conditions
Language Development, Learning
Interventions
Active transcranial electrical stimulation (tES), Sham transcranial electrical stimulation (tES)
Device
Lead sponsor
General Neuro Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

4 mA tDCS, Estrogen, and Leg Muscle Fatigability

NCT04471805
View directory record Official record
Conditions
Healthy
Interventions
Sham transcranial direct current stimulation 4 mA, Transcranial direct current stimulation 4 mA
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Sep 30, 2026, 10:58 PM EDT
Terminated Not applicable Interventional Results available

Non-invasive Brain Stimulation in Adults Who Stutter

NCT03437512
View directory record Official record
Conditions
Stuttering, Developmental
Interventions
Anodal tDCS, Fluency training, Sham tDCS
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Sep 30, 2026, 10:58 PM EDT
Completed Phase 1Phase 2 Interventional

Transcranial Direct Current Stimulation (TDCS) for Facilitating Swallowing Improvement After an Acute Unilateral Hemispheric Stroke

NCT01132066
View directory record Official record
Conditions
Dysphagia
Interventions
tDCS, Sham
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 28, 2014 · Synced Sep 30, 2026, 10:58 PM EDT
Terminated Not applicable Interventional Results available

Auditory Control Enhancement (ACE) in Schizophrenia

NCT06155695
View directory record Official record
Conditions
Auditory Hallucinations
Interventions
Transcranial Direct Current Stimulation (tDCS), Auditory Cognitive Control Training (ACCT)
Device · Behavioral
Lead sponsor
Brian A Coffman, PhD
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Active, not recruiting Not applicable Interventional

Music and Brain Stimulation for Upper Extremity Performance in Patients With Corticobasal Syndrome

NCT05073471
View directory record Official record
Conditions
Corticobasal Syndrome, Upper Extremity Dysfunction
Interventions
Patterned Sensory Enhancement (PSE), Transcranial Direct Current Stimulation (tDCS)
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Transcranial Direct Current Stimulation Intensity on Leg Muscle Fatigability in Healthy Adults

NCT04321304
View directory record Official record
Conditions
Healthy
Interventions
Sham transcranial direct current stimulation, Transcranial direct current stimulation at 2 mA, Transcranial direct current stimulation at 4 mA
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 30 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Sep 30, 2026, 10:58 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Effectiveness of tDCS in the Management of Perioperative Pain

NCT01861587
View directory record Official record
Conditions
Post-Operative Pain
Interventions
tDCS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 30, 2026, 10:58 PM EDT
Recruiting Not applicable Interventional

Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder

NCT07318480
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence, Substance Use Disorder (SUD)
Interventions
Transcranial Direct Current Stimulator (tDCS), Cognitive Reappraisal Training
Device · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Withdrawn Not applicable Interventional

Transcranial Electrical Stimulation for Mal de Debarquement Syndrome

NCT02540616
View directory record Official record
Conditions
Mal de Debarquement Syndrome
Interventions
Transcranial Electrical Stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Sep 30, 2026, 10:58 PM EDT
Active, not recruiting Not applicable Interventional

Optimization of NIBS for Diabetic Neuropathy Neuropathic Pain

NCT03625752
View directory record Official record
Conditions
Diabetic Neuropathies, Chronic Pain
Interventions
Active Comparator: Active tDCS + Active TUS, Sham
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
40 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation in Conjunction With Individualized Physical Therapy for Individuals With Chronic Knee Pain

NCT06132412
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
transcranial direct current stimulation, physical therapy
Device · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Terminated Not applicable Interventional

tDCS in Pediatric Acquired Brain Injury

NCT03618849
View directory record Official record
Conditions
Acquired Brain Injury, Disorders of Consciousness
Interventions
tDCS
Device
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
5 Years to 17 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Sep 30, 2026, 10:58 PM EDT
Terminated Not applicable Interventional

Neuromodulation and Cognitive Training for Substance Use Disorders

NCT04426214
View directory record Official record
Conditions
Stimulant Use, Alcohol Use Disorder
Interventions
tDCS, Cognitive Training
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Recruiting Not applicable Interventional

Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression

NCT06132581
View directory record Official record
Conditions
Major Depressive Disorder, Anhedonia
Interventions
Delta-beta tACS via the Neurocare Direct Current Stimulator Multi-Channel 4, Theta-gamma tACS via the Neurocare Direct Current Stimulator Multi-Channel 4, Sham tACS via the Neurocare Direct Current Stimulator Multi-Channel 4
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Recruiting Not applicable Interventional

Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

NCT05062369
View directory record Official record
Conditions
Alcohol Use Disorder, Addiction
Interventions
TaskFlow Transcranial Electrical Stimulation device, Executive Function Focused Cognitive Training
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 30, 2026, 10:58 PM EDT
Recruiting Not applicable Interventional

Individualized Neuro-Modulation Paired With Cerebellar Therapy

NCT07642856
View directory record Official record
Conditions
Cerebellar Ataxia, Cerebellar Diseases, Cerebellar Stroke, Cerebellar Tumor
Interventions
Therapy
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 30, 2026, 10:58 PM EDT
Completed Not applicable Interventional

Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)

NCT00521196
View directory record Official record
Conditions
Migraine
Interventions
DC Stimulator (Transcranial Direct Current Stimulator)
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Sep 30, 2026, 10:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

tDCS-Augmented Exposure Therapy for Pathological Fear

NCT03095482
View directory record Official record
Conditions
Specific Phobias
Interventions
Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy
Device · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 8, 2020 · Synced Sep 30, 2026, 10:58 PM EDT