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ClinicalTrials.gov public records Last synced Oct 4, 2026, 6:41 PM EDT

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Showing 121–144 of 170 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: transcranial direct current stimulation or SHAM Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Cerebellar TDCS for SRPCS Treatment

NCT04760899
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 30 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Transcranial Direct Current Stimulation (tDCS) in Chronic Corneal Pain

NCT01575002
View directory record Official record
Conditions
Corneal Pain, Chronic Pain, Neuropathic Pain
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 4, 2026, 6:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults

NCT04437251
View directory record Official record
Conditions
Vascular Accident, Brain, CVA (Cerebrovascular Accident), Gait, Hemiplegic, Spastic Lower Extremity Weakness
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
21 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional

A Study of Cerebral Perfusion With tDCS in Chronic Hypoperfusion

NCT06477107
View directory record Official record
Conditions
Moyamoya Syndrome, Moyamoya Disease, Atheroscleroses, Cerebral
Interventions
Soterix® 4x1HD-TDCS, Soterix® 1x1 tDCS, Cognitive training program
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Transcranial Direct Current Stimulation (tDCS) Coupled With Constraint Induced Movement Therapy in Stroke Patient

NCT01143649
View directory record Official record
Conditions
Stroke, Healthy
Interventions
transcranial direct current stimulation (tDCS), constraint induced movement therapy (CIMT), transcranial alternating current stimulation (tACS)
Device · Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

tDCS to Lower Neuropathic Pain and Fatigue in People With Multiple Sclerosis

NCT03870048
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment

NCT02596906
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
50 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Oct 4, 2026, 6:41 PM EDT
Not listed Not applicable Interventional

Treatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy

NCT04934371
View directory record Official record
Conditions
Tinnitus, Subjective, Hyperacusis, Hearing Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham TDCS
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Nicotine Withdrawal Symptoms and Smoking Relapse

NCT01511614
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Transcranial Direct Current Stimulation, sham, Nicotine patch, Placebo patch, Varenicline Pill, Placebo pill, Motivational Interviewing
Device · Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 31, 2024 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

The Effects of Noninvasive Brain Stimulation on Physical and Mental Functioning in Older Adults

NCT02436915
View directory record Official record
Conditions
Aging
Interventions
Real tDCS, Sham tDCS
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 5, 2019 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Non Invasive Brain Stimulation for PTSD

NCT02442843
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 88 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 4, 2026, 6:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

NCT04122001
View directory record Official record
Conditions
Alzheimer Disease, Early Onset, Atypical Alzheimer's Disease, Logopenic Progressive Aphasia
Interventions
Active, in-person HD-tDCS or active remote tDCS, Sham, Word List Learning Intervention (WordLLI)
Device · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
45 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Active, not recruiting No phase listed Interventional Results available

Effects of tDCS and TUS on the Perception of Pain and Functional Limitations Due to Non-Specific Chronic Low Back Pain

NCT02954432
View directory record Official record
Conditions
Chronic Pain, Chronic Low Back Pain
Interventions
transcranial Direct Current Stimulation (tDCS), Transcranial Ultrasound (TUS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting Phase 2 Interventional

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

NCT05446584
View directory record Official record
Conditions
Mild Cognitive Impairment, Amnestic Mild Cognitive Disorder, Amnestic Mild Cognitive Impairment, Mild Traumatic Brain Injury, Concussion, Brain
Interventions
High Definition Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
55 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1

NCT06601686
View directory record Official record
Conditions
Healthy
Interventions
Transcranial electrical stimulation (TES), Transcranial electrical stimulation with temporal interference (TES-TI), Sham stimulation
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury

NCT01795079
View directory record Official record
Conditions
Burn Injury, Chronic Pain, Pruritus, Itching
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting Not applicable Interventional

Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder

NCT07318480
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence, Substance Use Disorder (SUD)
Interventions
Transcranial Direct Current Stimulator (tDCS), Cognitive Reappraisal Training
Device · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Phase 2 Interventional

TDCS to Reduce Craving in Cocaine Addiction- Phase 2 Study

NCT04994821
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence
Interventions
transcranial direct current stimulator (tDCS), Cognitive Reappraisal
Device · Behavioral
Lead sponsor
Soterix Medical
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 4, 2026, 6:41 PM EDT
Completed No phase listed Observational

Transcranial Direct Current Stimulation and Autism

NCT01603225
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
14 Years to 79 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 4, 2026, 6:41 PM EDT
Withdrawn Not applicable Interventional

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

NCT02622945
View directory record Official record
Conditions
Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Priming Expectations and Motor Learning With tDCS

NCT06039605
View directory record Official record
Conditions
Expectations, Motor Learning
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Transcranial Random Noise Stimulation on Motor Learning in Typically Developing Adolescents

NCT06267339
View directory record Official record
Conditions
Children
Interventions
transcranial random noise stimulation, Sham stimulation
Device
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
10 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting Phase 2 Interventional

Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke

NCT06440707
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
High-definition Cathodal Transcranial Direct Current Stimulation (HD C-tDCS), Sham tDCS
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
3
States / cities
Los Angeles, California • Baltimore, Maryland • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional

Targeted Noninvasive Brain Stimulation (T-NIBS) to Improve Hand Motor Functions in Acquired Brain Injury

NCT04057105
View directory record Official record
Conditions
Upper Extremity Dysfunction, Traumatic Brain Injury
Interventions
Active High-definition Transcranial Direct Current Stimulation (HD-tDCS), MusicGlove
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 4, 2026, 6:41 PM EDT