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ClinicalTrials.gov public records Last synced Oct 10, 2026, 2:08 PM EDT

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Showing 49–72 of 108 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: transcranial direct current stimulator (tDCS) Clear all
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy

NCT05419999
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Soterix 1x1 tDCS mini CT, Sham Soterix 1x1 tDCS Mini CT, Written Exposure Therapy (WET)
Device · Other · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional

TDCS for Cocaine Addiction Craving

NCT03833583
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence
Interventions
Soterix Medical mini-CT tDCS stimulator
Device
Lead sponsor
Soterix Medical
Industry
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Self Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

NCT03425019
View directory record Official record
Conditions
Knee Osteoarthritis, Chronic Pain
Interventions
Soterix 1x1 tDCS mini-CT Stimulator device
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
50 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2021 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

NCT02427672
View directory record Official record
Conditions
Antisocial Behavior, Aggression
Interventions
Transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SMART Stimulation: Precision Neuromodulation of Cognition in Older Adults

NCT05377411
View directory record Official record
Conditions
Aging
Interventions
tDCS, cognitive training
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Due to Burn Injury

NCT01404026
View directory record Official record
Conditions
Pain, Burn Injury
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Single-arm, Open-label, Phase II Trial of HD-tDCS in Fibromyalgia Patients

NCT01842009
View directory record Official record
Conditions
Fibromyalgia, Chronic Pain
Interventions
High Definition transcranial Direct Current Stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 10, 2026, 2:08 PM EDT
Terminated Phase 1Phase 2 Interventional

Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression

NCT03999736
View directory record Official record
Conditions
Major Depressive Disorder, Anxiety
Interventions
transcranial direct current stimulation using a Soterix mini-CT device
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 28 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2021 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression

NCT04948944
View directory record Official record
Conditions
Depression, Anxiety and Fear
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) and Parkinson's Disease

NCT01100762
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Cranial Electric Stimulation (CES), Treadmill, CES and Treadmill
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study

NCT03122236
View directory record Official record
Conditions
Mobility Limitation, Cognitive Impairment
Interventions
Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Sham Transcranial Direct Current Stimulation (Sham tDCS), Active Transcranial Direct Current Stimulation (Active tDCS)
Behavioral · Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 110 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 10, 2026, 2:08 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia

NCT04486586
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 10, 2026, 2:08 PM EDT
Active, not recruiting Not applicable Interventional

Treatment Outcomes With tDCS in Post-Stroke Aphasia

NCT03929432
View directory record Official record
Conditions
Aphasia
Interventions
Active Transcranial Direct Current Stimulation with SLT, Sham Transcranial Direct Current Stimulation with SLT
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Nicotine Withdrawal Symptoms and Smoking Relapse

NCT01511614
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Transcranial Direct Current Stimulation, sham, Nicotine patch, Placebo patch, Varenicline Pill, Placebo pill, Motivational Interviewing
Device · Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 31, 2024 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Remotely Supervised tDCS for Slowing ALS Disease Progression

NCT04866771
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham tDCS + anodal tDCS
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 10, 2026, 2:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Investigating Accelerated Learning in Healthy Subjects: Trigeminal Nerve Stimulation

NCT03138590
View directory record Official record
Conditions
Healthy Adults
Interventions
Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Oct 10, 2026, 2:08 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

TDCS-Augmented Prolonged Exposure Therapy

NCT04327362
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD, Anxiety, Depression
Interventions
Transcranial Direct Current Stimulation (tDCS), Prolonged Exposure Therapy
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Treating Civilian Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation (ciTBI-HDtDCS)

NCT05408975
View directory record Official record
Conditions
Traumatic Brain Injury, Word Finding Difficulty, Acquired Brain Injury, Cognitive Change
Interventions
Active Transcranial direct current stimulation, Sham Transcranial direct current stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 85 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 10, 2026, 2:08 PM EDT
Recruiting Not applicable Interventional

Neurostimulation for the Treatment of Post-Stroke Aphasia

NCT05194566
View directory record Official record
Conditions
Post-stroke Aphasia
Interventions
tACS
Device
Lead sponsor
QVITI S.A.
Industry
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

tDCS Intervention in Primary Progressive Aphasia

NCT02606422
View directory record Official record
Conditions
Primary Progressive Aphasia, MCI, FTD
Interventions
Active HD-tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)

NCT00521196
View directory record Official record
Conditions
Migraine
Interventions
DC Stimulator (Transcranial Direct Current Stimulator)
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Phase 2 Interventional Results available

Robots Paired With tDCS in Stroke Recovery

NCT01726673
View directory record Official record
Conditions
Stroke
Interventions
Transcranial Direct Current Stimulation (tDCS), Placebo sham
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2021 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

tDCS and Cognition in Adults With Multiple Sclerosis or Encephalitis

NCT02538094
View directory record Official record
Conditions
Multiple Sclerosis, Encephalitis
Interventions
Sham Transcranial direct current stimulation, Anodal Transcranial direct current stimulation
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 10, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiological and Functional Mechanisms of Motor Control and Learning

NCT03190590
View directory record Official record
Conditions
Transcranial Direct Current Stimulation
Interventions
tDCS-NeuroConn., TMS - Magstim., Sham tDCS
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 10, 2026, 2:08 PM EDT