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ClinicalTrials.gov public records Last synced Nov 11, 2026, 7:45 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 127 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: transversus abdominis plane block Clear all

Conditions: Breast - Female
Interventions: Transversus Abdominis Plane (TAP) block, Nimbus Infusion Pump IV Administration, Bupivacaine infusion, Acetominophen, Hydromorphone, Oxycodone, Ondansetron; Procedure · Device · Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Stanford, California

Conditions: Analgesia, Surgery
Interventions: TAP Anesthesia, Surgeon-Initiated Local Anesthetic; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older · Female only
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Pain, Postoperative, Delirium, Anesthesia, Local
Interventions: Ropivacaine HCL, sodium chloride; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Umbilical Hernia, Obesity
Interventions: TAPB Group, RSB Group, conversion to general anesthesia; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 99 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer, Gastric (Cardia, Body) Cancer, Biliary Tract Cancer, Pancreatic Cancer Resectable, Gynecologic Cancers, Gastrointestinal Cancers, Colorectal Cancer, Minimally Invasive Surgical Procedures
Interventions: Local Anesthesia, Laparoscopic Transversus Abdominis Plane block; Procedure
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 18 Years to 89 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Prostate CA
Interventions: Dexamethasone, TAP block; Drug · Procedure
Lead sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc.; Other
Eligibility: 18 Years to 85 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Post Operative Pain, Gynecologic Cancer
Interventions: Liposomal bupivacaine, Bupivacain; Drug
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obstetrical Complications From Sedation During Parturition
Interventions: Bupivicaine; Drug
Lead sponsor: New York Presbyterian Brooklyn Methodist Hospital; Other
Eligibility: 18 Years to 50 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Perioperative Opioid Sparing Techniques
Interventions: Intrathecal Morphine Block, Bilateral Quadratus Lumborum Block, Bilateral Transverse Abdominis Plane Block; Procedure
Lead sponsor: University of Tennessee Graduate School of Medicine; Other
Eligibility: 18 Years to 80 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Ovarian Cancer, Fibroids, Uterine Cancer
Interventions: Bupivacaine, Liposomal bupivacaine; Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Orange, California

Conditions: Postoperative Pain
Interventions: Gabapentin, TAP Block; Drug · Procedure
Lead sponsor: State University of New York - Downstate Medical Center; Other
Eligibility: 18 Years to 60 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Postoperative Pain, Postoperative Nausea and Vomiting
Interventions: Ropivacaine, Placebo, Transversus Abdominis Plane Block; Drug · Other · Procedure
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Nephrectomy
Interventions: Transverses Abdominis Plane (TAP) block, Quadratus Lumborum (QL) block, Surgeon Infiltration using Exparel; Procedure
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Pain, Postoperative
Interventions: ropivacaine; Drug
Lead sponsor: Liberman, Eric, D.O.; Individual
Eligibility: 18 Years and older · Female only
Enrollment: 220 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Livingston, New Jersey

Conditions: Pain, Postoperative, Cesarean Section
Interventions: Ropivacaine, TAP block, QL block, ESP block; Drug · Procedure · Biological
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Appendicitis
Interventions: Ropivacaine, Bupivacaine; Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: Not listed
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Postoperative Pain, Surgery, Anesthesia, Local
Interventions: Exparel 266 MG Per 20 ML Injection; Drug
Lead sponsor: St. Luke's Hospital, Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Bethlehem, Pennsylvania

Conditions: Substance Use Disorder (SUD)
Interventions: Regional Anesthesia, Hydromorphone Patient Controlled Analgelsic, Epidural local anesthetic infusion; Drug · Procedure
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Milwaukee, Wisconsin

Conditions: Liver and Intrahepatic Bile Duct Disorder
Interventions: Bupivacaine, Fentanyl, Hydromorphone Hydrochloride, Implanted Medical Device, Liposomal Bupivacaine, Questionnaire; Drug · Device · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pain, Postoperative, Major Abdominal Surgery
Interventions: TAP block, Epidural analgesia, EXPAREL, Bupivacaine; Procedure · Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 514 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Cleveland, Ohio

Conditions: Malignant Neoplasm of Abdomen, Surgery
Interventions: Exparel 1.33% (20ml Volume), 0.125% bupivicaine with 2 mcg/ml Fentanyl.; Drug
Lead sponsor: Corewell Health West; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: POSTOPERATIVE PAIN
Interventions: Surgical TAP block, Conventional TAP block, 0.5% ropivacaine; Procedure · Drug
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Bariatric Surgery, Transverse Abdominal Plane Regional Blocks
Interventions: Transverse abdominal plane block, Ropivacaine; Procedure · Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Opioid Use, Pain, Acute
Interventions: Liposomal bupivacaine (LB), Dexamethasone and methylprednisolone (CG), Control group (Bupivacaine)- (BPG); Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 147 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Search by objective public record fields.

Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

Transversus Abdominis Plane Block Compared to Local Anesthetic Wound Infiltration in Gynecologic Oncology Surgery

Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anesthetic, Narcotic Dosing, and Pain Scores

Abdominal Wall Block Study

Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

Evaluation of Addition of Dexamethasone to Transversus Abdominis Plane (TAP) Peripheral Nerve Block

Pilot: Intraoperative TAP Block and Post-operative Pain Control for Minimally Invasive Hysterectomy for Endometrial Cancer

Transversus Abdominis Plane (TAP) Block for Post Caesarian Pain

Efficacy of Perioperative Opioid Sparing Techniques on Time to Initiation of Chemotherapy

Pilot Study of Liposomal Bupivacaine Redosing in Patients Undergoing Major Gynecologic Procedures

Combination of Preoperative Gabapentin and TAP Blocks in Decreasing Postoperative Pain

Intraoperative Transversus Abdominis Plane Block for Gynecologic Surgery (GYNTAP)

Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy

Efficacy of Transversus Abdominis Plane Block Versus Local Injection of Pain Medication

Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section

Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies

Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control

Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.

Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery

Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine

TAP Versus Thoracic Epidural in Major Abdominal Resections

Comparative Study of Two Different Techniques to Perform TAP-blocks

Regional TAP Block for Bariatric Patients

TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery