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ClinicalTrials.gov public records Last synced Oct 16, 2026, 9:15 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 673–696 of 3,321 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: treatment-as-usual Clear all
Recruiting Phase 1Phase 2 Interventional

Breakthrough - T1DM and Chronic Kidney Disease

NCT07592000
View directory record Official record
Conditions
Diabete Type 1, Chronic Kidney Disease
Interventions
Tegoprubart, Islet Cell Transplant
Drug · Biological
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
2
States / cities
Miami, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 16, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional

Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A

NCT06223867
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Self Harm
Interventions
Jaspr App + JAH, ETAU
Device · Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
670 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 16, 2026, 9:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Brief Online Study Abroad Alcohol Intervention

NCT03928067
View directory record Official record
Conditions
Alcohol Abuse
Interventions
PNF + SAF
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 25 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Caregiver-Guided Pain Management Training in Palliative Care

NCT02430467
View directory record Official record
Conditions
Advanced Cancer
Interventions
Caregiver-guided pain management training (CG-PMT), Enhanced treatment-as-usual (TAU)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 25, 2023 · Synced Oct 16, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial

NCT07176000
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Patient Navigation, Educational Intervention, Best Practice, Interview, Survey Administration, Electronic Health Record Review
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
237 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Auburn, Washington • Shelton, Washington
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Gum Infection on Heart Disease

NCT00093236
View directory record Official record
Conditions
Cardiovascular Disease, Periodontal Disease
Interventions
Early Periodontal Treatment, Usual Dental Hygiene
Procedure
Lead sponsor
Boston University
Other
Eligibility
20 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 16, 2026, 9:15 AM EDT
Recruiting Phase 2 Interventional

Y-90 Treatment Response Using Transarterial Radioembolization

NCT07145801
View directory record Official record
Conditions
HCC, Hepatocellular Carcinoma, Liver Cancer, Hepatic Neoplasm, Primary Liver Cancer, Liver Neoplasm
Interventions
Lumason, Sonazoid
Diagnostic Test
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 16, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)

NCT06501781
View directory record Official record
Conditions
HIV Infections, Substance Use
Interventions
Peer Activate-LAI, Standard of Care HIV treatment or prevention with LAI-PrEP/ART
Behavioral · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Children's Attention Deficit Disorder With Hyperactivity (ADHD) Telemental Health Treatment Study

NCT00830700
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
CATMH intervention
Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
5 Years to 12 Years
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 11, 2014 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional Results available

Robotic Walking Device to Improve Mobility in Parkinson's Disease

NCT03751371
View directory record Official record
Conditions
Parkinson Disease
Interventions
Training with HWA device, Usual Care
Device · Other
Lead sponsor
Ohio State University
Other
Eligibility
50 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 16, 2026, 9:15 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Assessing Interventions to Increase Tdap Acceptance for Non-birthing Partners in Pregnancy

NCT06135636
View directory record Official record
Conditions
Non-birthing Partner Vaccination in Pregnancy, Tdap - Tetanus, Diphtheria and Acellular Pertussis Vaccination, Vaccine Exposure During Pregnancy
Interventions
Education, Vaccine administration
Behavioral · Biological
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
19 Years to 50 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 16, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

mHealth Mindfulness With Patients With Serious Illness and Their Caregivers

NCT05040711
View directory record Official record
Conditions
Caregiver Stress Syndrome, Anxiety
Interventions
Mindfulness Coach, Active Comparator
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
21 Years and older
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
3
States / cities
Livingston, New Jersey • Monroe, New Jersey • New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Using Artificial Intelligence to Measure and Optimize Adherence in Patients on Anticoagulation Therapy.

NCT02599259
View directory record Official record
Conditions
Stroke
Interventions
Monitored (M+)
Device
Lead sponsor
AiCure
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Oct 16, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NAFLD Clinical Care Pathway

NCT06671886
View directory record Official record
Conditions
NAFLD, MASLD
Interventions
E-trigger
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet-based Treatment of Early Childhood Fecal Incontinence

NCT00067769
View directory record Official record
Conditions
Encopresis
Interventions
Internet-based intervention UCanPoopToo, treatment as usual
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
6 Years to 12 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 7, 2015 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Awake-Prone Positioning Strategy for Hypoxic Patients With COVID-19

NCT04547283
View directory record Official record
Conditions
Covid19, Respiratory Failure
Interventions
Usual Care, APPS
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Phase 2 Interventional

Mobile Technology & Online Tools to Track Adherence in Chronic Illness Patients

NCT02861157
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Planet T1D
Behavioral
Lead sponsor
3-C Institute for Social Development
Industry
Eligibility
12 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Phase 2 Interventional Results available

Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma

NCT04151667
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Daratumumab Injection, Dexamethasone Oral, Lenalidomide Pill, Bortezomib Injection
Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
65 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional Results available

De-implementing Inhaled Steroids to Improve Care and Safety in COPD

NCT02896257
View directory record Official record
Conditions
Treatment of Chronic Obstructive Pulmonary Disease
Interventions
Guideline treatment recommendations
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
2
States / cities
Bedford, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 16, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional

The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV

NCT07226128
View directory record Official record
Conditions
HIV, Depression in Adults, Insulin Resistance, Cognitive Behavior Therapy
Interventions
Internet cognitive behavioral therapy (iCBT-D), Active Control (AC)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 16, 2026, 9:15 AM EDT
Active, not recruiting Not applicable Interventional

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

NCT03033992
View directory record Official record
Conditions
Malignant Glioma, Ependymoma, Diffuse Intrinsic Pontine Glioma
Interventions
Optune System (NovoTTF-200A System, Tumor Treating Fields, TTFields), Concurrent Optune and RT followed by Optune System alone
Device · Combination Product
Lead sponsor
Children's Oncology Group
Network
Eligibility
3 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2032
U.S. locations
11
States / cities
Phoenix, Arizona • Los Angeles, California • Palo Alto, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 16, 2026, 9:15 AM EDT
Completed Not applicable Interventional

A Brief Mindfulness-Based Intervention for Suicidal Ideation

NCT04099173
View directory record Official record
Conditions
Suicidal Ideation, Psychiatric Disorder, Addiction
Interventions
Brief Mindfulness Based Intervention
Behavioral
Lead sponsor
VA Salt Lake City Health Care System
Federal
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Oct 16, 2026, 9:15 AM EDT
Terminated Not applicable Interventional

Pharmacogenomics for Improving Pediatric ADHD Treatment

NCT03730870
View directory record Official record
Conditions
Attention Deficit Disorders With Hyperactivity
Interventions
Pharmacogenomics report
Diagnostic Test
Lead sponsor
Clinical and Translational Genome Research Institute, Inc.
Other
Eligibility
6 Years to 18 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Hamilton, New Jersey • Mountainside, New Jersey • Toms River, New Jersey
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Oct 16, 2026, 9:15 AM EDT
Not yet recruiting Not applicable Interventional

Radiographic Evaluation of Tumor Biology During Neoadjuvant Radiotherapy for Sarcoma

NCT07487870
View directory record Official record
Conditions
Sarcoma
Interventions
MRI
Diagnostic Test
Lead sponsor
Andrew Frankart
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 16, 2026, 9:15 AM EDT