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Showing 25–37 of 37 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: very low nicotine content cigarettes Clear all

Conditions: Nicotine Dependence
Interventions: Very Low Nicotine Content Cigarettes, Intermediate Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes; Other
Lead sponsor: Duke University; Other
Eligibility: 15 Years to 25 Years
Enrollment: 182 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cigarette Smoking, E-cigarette Use
Interventions: Nicotine Content, Illegal cigarette price, E-cigarette price; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 21 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Chronic Pain, Smoking, Cigarette
Interventions: SPECTRUM NRC 102/103 investigational cigarettes, SPECTRUM NRC 600/601 investigational cigarettes; Other
Lead sponsor: Duke University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking
Interventions: Nicotine content; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 21 Years to 29 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smoking, Smoking, Cigarette, E-Cig Use, Nicotine Dependence
Interventions: very low nicotine content cigarettes, normal nicotine content cigarettes, Study e-cigarette; Other
Lead sponsor: Duke University; Other
Eligibility: 21 Years and older
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cigarette Smoking
Interventions: Nicotine Patch, SPECTRUM Nicotine Research Cigarettes (0.07 mg), MCE-; Drug · Behavioral
Lead sponsor: Francis McClernon, Ph.D.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Use Disorder
Interventions: Very low nicotine content cigarettes; Other
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 775 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Baltimore, Maryland • Burlington, Vermont

Conditions: Nicotine Dependence
Interventions: Very low nicotine content cigarettes, Standard nicotine content cigarettes; Other
Lead sponsor: Brown University; Other
Eligibility: 15 Years to 19 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Tobacco Use Disorder
Interventions: Varying the nicotine content of cigarettes, E-Cigarettes; Other
Lead sponsor: University of Vermont; Other
Eligibility: 21 Years to 44 Years · Female only
Enrollment: 326 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Baltimore, Maryland • Burlington, Vermont

Conditions: Tobacco Use Disorder
Interventions: Very low nicotine content cigarettes; Other
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 2
States / cities: Lexington, Kentucky • Burlington, Vermont

Conditions: Tobacco Dependence
Interventions: Very low nicotine content cigarettes, Normal nicotine content cigarettes; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 21 Years to 60 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Tobacco Use Disorder
Interventions: Very low nicotine content cigarettes; Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 775 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Providence, Rhode Island • Burlington, Vermont

Conditions: Nicotine Dependence, ADHD
Interventions: Very low nicotine content cigarettes, Conventional nicotine content cigarettes; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Durham, North Carolina • Pittsburgh, Pennsylvania