Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 11, 2026, 3:59 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 839 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: weight loss/ exercise Clear all

Conditions: Osteoarthritis, Knee
Interventions: Diet and Exercise; Behavioral
Lead sponsor: Wake Forest University; Other
Eligibility: 50 Years and older · Female only
Enrollment: 1,230 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 3
States / cities: Boston, Massachusetts • Chapel Hill, North Carolina • Winston-Salem, North Carolina

Conditions: Overweight, Obesity, Insulin Resistance
Interventions: ACTION, Usual care; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 13 Years to 20 Years
Enrollment: 145 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Overweight and Obesity
Interventions: WW Only, WW + PolyRules!; Behavioral
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: West Hollywood, California

Conditions: Obesity, Weight Loss, Diet Modification, Aging, Weight Change, Body, Dietary Habits, Osteopenia, Osteoporosis, Bone Loss, Fractures, Bone
Interventions: Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement, 6-month NutraBio™ 100% Whey Protein Isolate Supplement, 18-month NutraBio™ 100% Whey Protein Isolate Supplement; Behavioral · Dietary Supplement
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 65 Years to 85 Years
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Overweight and Obesity
Interventions: SMART 2.0; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 35 Years
Enrollment: 638 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Health Behavior
Interventions: health coaching; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 21 Years to 100 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Obesity, Type 2 Diabetes
Interventions: Gastric Banding, Medical Weight Loss, Gastric Bypass; Procedure · Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 64 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obesity
Interventions: Peer-Led Group Lifestyle Balance, Usual Care Services; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 314 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Hypogonadism, Severe Obesity
Interventions: Anastrazole, weight loss; Drug · Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 35 Years to 65 Years · Male only
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Childhood Obesity
Interventions: m-health approach; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 5 Years to 14 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Hammond, Louisiana

Conditions: Overweight and Obesity, Health Behavior
Interventions: mobile Health and Wellness Coaching, Usual Care; Behavioral
Lead sponsor: Edward Via Virginia College of Osteopathic Medicine; Other
Eligibility: 19 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Auburn, Alabama

Conditions: Chest Pain
Interventions: Aspirin, Lisinopril, Simvastatin, Lovaza, Therapeutic Lifestyle Changes; Drug · Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 30 Years to 90 Years · Female only
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Obesity, Weight Loss
Interventions: behavior weight loss; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 21 Years to 45 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2002
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Diabetes, Obesity
Interventions: weight loss/ exercise; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 30 Years to 55 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypertension
Interventions: High blood pressure treatment; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 10 Years to 18 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Overweight, Metabolic Syndrome X
Interventions: Placebo, Cr-400, Cr-800, PE-500, PE-1000; Dietary Supplement
Lead sponsor: Kerry Group P.L.C; Industry
Eligibility: 30 Years to 65 Years
Enrollment: 112 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: College Station, Texas

Conditions: Obesity, Childhood
Interventions: Regulation of Cues +, Family Based Behavioral Treatment, Health Education; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 7 Years to 12 Years
Enrollment: 280 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 2
States / cities: La Jolla, California • Minneapolis, Minnesota

Conditions: Weight Gain, Weight Loss
Interventions: Gestational weight gain intervention, Postpartum weight loss intervention; Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older · Female only
Enrollment: 430 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: San Antonio, Texas

Conditions: Dynapenia, Obesity
Interventions: Weight Loss, Dairy Protein, Low intensity exercise; Behavioral · Dietary Supplement
Lead sponsor: Duke University; Other
Eligibility: 60 Years and older
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
Interventions: POPOP (preoperative patient optimization program), SOC (standard of care); Other
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 80 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Cancer Survivors, Cancer of Breast, Body Weight, Overweight and Obesity
Interventions: Behavioral Weight-loss Program Via Telehealth, Behavioral Weight-Loss Program Via Telehealth - Weight Measures, Validated Surveys of Patient-Reported Outcomes; Behavioral
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity
Interventions: Weight loss; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 25 Years to 59 Years
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: New York, New York • Philadelphia, Pennsylvania

Conditions: Overweight, Obesity
Interventions: lifestyle intervention; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Diabetes Mellitus, Type 2
Interventions: Weight reduction training, PPG training, discrete BG feedback, continuous BG feedback; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 21 Years to 80 Years
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Charlottesville, Virginia

Search by objective public record fields.

The Osteoarthritis Prevention Study

Adolescents Committed to Nutrition and Physical Activity

Inhibitory Control Adult Weight Management

Utilizing Protein During Weight Loss to Impact Physical Function and Bone

SMART 2.0: Social Mobile Approaches to Reducing weighT in Young Adults

My Health Coach Study

Improving Diabetes Through Lifestyle and Surgery

Peer-Led Healthy Lifestyle Program in Supportive Housing

Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot)

Healthy Kids I-PAL

A Mobile Health and Wellness Coaching Intervention for Weight Loss

Women With Chest Pain and Normal Coronary Arteries Study

Dose-Response of Exercise on Long-Term Weight Loss

Mitochondrial Impairment in Muscle Insulin Resistance

Effect of High Blood Pressure and Antihypertensive Treatment on Brain Functioning in Children

Impact of Chromium, Phyllanthus Emblica, and Shilajit on Cardiovascular Health, Fitness, and Weight Loss During Exercise and Diet Programs

Family, Responsibility, Education, Support, and Health for Food Responsiveness

Gestational Weight Gain and Postpartum Weight Loss in Active Duty Women (Moms Fit 2 Fight)

An Enhanced Protein (Dairy) Weight Loss Intervention for Dynapenic Obesity: Impact on Muscle Quality and Composition

Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA

Telehealth Weight Loss Program for Breast Cancer Survivors

A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program

FirstWIND: Weight Loss Interventions After Delivery

Treating Type 2 Diabetes by Reducing Postprandial Glucose Elevations: A Paradigm Shift in Lifestyle Modification