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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:04 PM EDT

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Showing 625–648 of 665 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: weight loss program Clear all
Not listed No phase listed Observational Accepts healthy volunteers

Obalon Balloon System Post-Approval Study

NCT03570034
View directory record Official record
Conditions
Obesity
Interventions
Obalon Balloon System
Device
Lead sponsor
Obalon Therapeutics, Inc.
Industry
Eligibility
22 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
15
States / cities
Fountain Valley, California • Glendale, California • Los Gatos, California + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Nutrisystem Meal Provision on Weight

NCT01252303
View directory record Official record
Conditions
Obesity
Interventions
Nutrisystem
Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
25 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 23, 2011 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional

PILI 'Ohana Project: Partnerships to Overcome Obesity Disparities in Hawaii (3-Year Pilot)

NCT01042886
View directory record Official record
Conditions
Overweight, Obesity
Interventions
PILI 'Ohana Lifestyle Program, Standard Behavioral Weight Loss Maintenance Program
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jan 6, 2010 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Evaluating the Effects Two Diets Combined With Exercise in Persons With Abdominal Obesity (The SHAPE5 Study)

NCT00990457
View directory record Official record
Conditions
Overweight, Obese, Sedentary, Abdominal Obesity
Interventions
Weight Loss Diets Plus Exercise
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
30 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 4, 2013 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Weight Watchers Online

NCT01888172
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Weight Watchers Online Program, Philips ActiveLink, Eating and Activity Newsletter
Behavioral · Device
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Providence, Rhode Island • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Education Session to Improve Program Adherence

NCT06428695
View directory record Official record
Conditions
Weight Management
Interventions
one-hour dietary self-monitoring tool education session
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 21, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional

Microrandomized Trial to Optimize Use of Burden-reducing Self-monitoring Approaches in Behavioral Obesity Treatment

NCT07228130
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Online Behavioral Obesity Treatment, Full Dietary Self-monitoring, Reduced-frequency Dietary Self-monitoring, Self-Monitoring of Dietary Lapses Only, Smartwatch-based Self-monitoring of Energy Intake, Self-monitoring of Body Weight Only
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Peau o le Vasa: Analysis of the Efficacy and Feasibility of the PILI Lifestyle Program (PLP) + Social Determinants of Health (SDOH) Intervention and Adaptation of SDOH Measures Pilot Study

NCT06471595
View directory record Official record
Conditions
Weight Loss Trial, Cardiometabolic Syndrome, Hypertension, Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus
Interventions
Partnership for Improving Lifestyle Intervention (PILI) Lifestyle Program + Social Determinants of Health (SDOH) Component
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Fayetteville, Arkansas • Springdale, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telephone Counseling and Numberless Scales to Overcome Barriers to Adolescent Weight Loss

NCT04241939
View directory record Official record
Conditions
Obesity
Interventions
Numberless BDS, Digital Scale, Modified Motivational Interviewing
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
12 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
League City, Texas • Webster, Texas
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Phone Coaching and Internet-delivered Weight Loss

NCT03867981
View directory record Official record
Conditions
Obesity
Interventions
Internet-based weight loss program, Brief phone coaching, Extended phone coaching
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Phase 3 Interventional Results available

Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects

NCT01764386
View directory record Official record
Conditions
Obesity, Overweight
Interventions
NB, CLI, Usual Care
Drug · Behavioral
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Eligibility
18 Years to 60 Years
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
15
States / cities
Denver, Colorado • St Louis, Missouri • Cary, North Carolina + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2015 · Synced Oct 21, 2026, 2:04 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Stepped Care for Weight Loss Maintenance

NCT06151145
View directory record Official record
Conditions
Obesity
Interventions
Usual care, SELF, STEP
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional Results available

Diabetes Data-Assisted Remission Trial (DDART)

NCT04663061
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Medical weight loss, Diabetes education, Continuous glucose monitoring
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional

PACE CALL: Weight Loss Study for Childhood Leukemia Survivors

NCT01253720
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Cancer, Obesity
Interventions
PACE CALL/Fit4Life
Behavioral
Lead sponsor
Huang, Jeannie, M.D.
Individual
Eligibility
7 Years to 18 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 26, 2016 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional Results available

Latinos Combating Diabetes

NCT01831921
View directory record Official record
Conditions
Pre Diabetes, Obesity, Metabolic Syndrome
Interventions
Lifestyle Weight Loss, Counseling
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of an Adaptive Treatment for Weight Loss in People With Prediabetes

NCT04745572
View directory record Official record
Conditions
PreDiabetes, Obesity
Interventions
High Carbohydrate Diet, Reduced Carbohydrate Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional

North Carolina WISEWOMAN: Weight-Wise Pilot Study

NCT00288301
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Weight loss intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 64 Years · Female only
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2010 · Synced Oct 21, 2026, 2:04 PM EDT
Suspended Phase 4 Interventional

Semaglutide to Reduce Atrial Fibrillation Burden

NCT05209165
View directory record Official record
Conditions
Atrial Fibrillation, Obesity, Overweight
Interventions
Semaglutide, Placebo
Drug
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a SlimFast Internet Behavioral Weight Loss Program

NCT00200304
View directory record Official record
Conditions
Obesity
Interventions
Internet weight loss with SlimFast and human counseling, Internet weight loss with SlimFast and computer counseling, Internet weight loss program with SlimFast
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
20 Years to 65 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2003
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 21, 2026, 2:04 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Self-Guided Mobile Intervention for Adults With Binge Eating and Obesity

NCT06817863
View directory record Official record
Conditions
Binge Eating Disorder Associated With Obesity, Binge Eating Disorder
Interventions
Digital
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 21, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Using a State-wide Initiative to Disseminate Effective Behavioral Weight Loss Strategies: Study 5

NCT02163252
View directory record Official record
Conditions
Obesity
Interventions
Standard, Early Intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 19, 2015 · Synced Oct 21, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional

Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)

NCT06569121
View directory record Official record
Conditions
Stroke, Acute, Stroke, Stroke, Cardiovascular, Stroke (CVA) or TIA, Stroke/Brain Attack
Interventions
Group Lifestyle Balance for People Post Stroke (GLB-CVA)
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional

Remotely Delivered, Community-Aligned Weight Loss Interventions Among Breast Cancer Survivors, ¡Vida! Trial

NCT05930483
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
Interventions
¡Vida! program, ¡Vida! Plus [¡Vida! + Experiential Learning (EL)], Health Coaching, Mailed Toolkits
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 21, 2026, 2:04 PM EDT
Terminated Not applicable Interventional Results available

Multimodal Treatment Strategy for Cancer Cachexia

NCT00625742
View directory record Official record
Conditions
Advanced Cancer, Cachexia
Interventions
Graded Resistance Training, Aerobic Exercise, Melatonin, Juven, Atenolol, Ibuprofen
Behavioral · Drug · Dietary Supplement
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2016 · Synced Oct 21, 2026, 2:04 PM EDT