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Showing 193–216 of 665 matching trials from the live ClinicalTrials.gov search.
Recruiting Not applicable Interventional Accepts healthy volunteers

The Osteoarthritis Prevention Study

NCT05946044
Conditions
Osteoarthritis, Knee
Interventions
Diet and Exercise
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
50 Years and older · Female only
Enrollment
1,230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
3
States / cities
Boston, Massachusetts • Chapel Hill, North Carolina • Winston-Salem, North Carolina
Conditions
Obesity & Overweight, Weight Loss, Preventative Health, Body Weight, Cardiovascular Disease Risk Factor
Interventions
Noom Weight, Free Tier, Education-only control, Semaglutide, Tirzepatide, Microdose semaglutide, Microdose tirzepatide
Behavioral · Drug
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
2,310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Princeton, New Jersey
Completed Not applicable Interventional

Preventing Diabetes

NCT05395377
Conditions
PreDiabetes
Interventions
Registered Dietitian/Nutritionist, Diabetes Prevention Program, Weight Watchers, Reimagined, DPP or RDN Counseling + Medication, Bariatric Surgery Evaluation
Behavioral · Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Danville, Pennsylvania
Conditions
Overweight/Obesity, Puberty, Health Behavior, Cardiometabolic Health
Interventions
Family-Based Treatment (FBT)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
6 Years to 8 Years · Female only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Conditions
VTE
Interventions
VTE REHABILITATION: High-Caloric Expenditure Exercise Training (HCE) and The Dietary Behavioral Weight Loss Intervention (BWL)
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
16 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Type 2 Diabetes
Interventions
Routine Care + Glycemic Excursion Minimization (RC+GEM), Routine Care (RC)
Behavioral · Other
Lead sponsor
Chiara Fabris, PhD
Other
Eligibility
30 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Charlottesville, Virginia
Conditions
Early Stage Breast Cancer
Interventions
POWER-remote, Self-directed
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance

NCT06785064
Conditions
Obesity Prevention, Weight Change, Weight Loss, Weight Loss Maintenance
Interventions
Reduced Food Variety (RFV), Home-based Resistance Training (HBRT), Buddy Training and Support (BTS), Acceptance and Commitment (ACT) Workshops
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
544 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions
Weight Loss Maintenance (Control vs. Reverse Diet)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Get Social: Randomized Trial of a Social Network Delivered Lifestyle Intervention

NCT02646618
Conditions
Weight Loss
Interventions
Get Social, Traditional, Smartphone
Behavioral · Device
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 65 Years
Enrollment
329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Storrs, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Integrating an Internet Weight Control Program Into Primary Care

NCT01606813
Conditions
Overweight, Obese
Interventions
Usual Care, Brief Physician Counseling, Referral and access to an internet weight control program, Brief follow up email notes from PCPs
Other · Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 70 Years
Enrollment
611 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

SMART: A Social and Mobile Weight Control Program for Young Adults

NCT01200459
Conditions
Obesity
Interventions
Social/mobile weight loss promotion intervention.
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 35 Years
Enrollment
404 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
La Jolla, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Approaches for Improving Long-term Weight Loss

NCT03799289
Conditions
Obesity
Interventions
Behavioral weight loss followed by yoga instruction, Behavioral weight loss followed by cooking/dietary education instruction
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)

NCT03406975
Conditions
Obesity, Hypertension, Diabetes Mellitus, Type 2
Interventions
Overstitch Endoscopic Suture System, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 65 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
9
States / cities
Orlando, Florida • Chicago, Illinois • Evanston, Illinois + 6 more
Conditions
Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis, Obesity
Interventions
Phase II: Lifestyle treatment, Phase II: Control treatment, Phase I: Observational studies
Behavioral · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
22 Years to 65 Years
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity, Weight Loss, GLP - 1
Interventions
Group Therapy Program, semaglutide, Phentermine-Topiramate, naltrexone and bupropion (combination)
Behavioral · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Overweight, Obese, Sedentary, Abdominal Obesity
Interventions
Weight Loss Diets Plus Exercise
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
30 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Attitudes Toward Food During a Weight Loss Intervention

NCT04586647
Conditions
Obesity, Weight Loss, Overweight and Obesity, Overweight or Obesity, Eating Behavior, Food Habits, Eating Disorder Symptom
Interventions
Noom Healthy Weight; mobile behavior change program for weight loss.
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Obesity
Interventions
Shape Up Rhode Island + Online Resources, Shape Up Rhode Island + Online Weight Loss Program, Shape Up Rhode Island + Online Weight Loss Program + Group sessions
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Choosing Healthy Activities and Lifestyle Management Through Portal Support

NCT05410353
Conditions
Weight Loss, Overweight and Obesity, Behavior, Health
Interventions
Active Intervention Group, Comparison Group
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
16 Years and older
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Obesity
Interventions
Comprehensive weight loss, Enhanced lifestyle changes, Tirzepatide, Naltrexone-Bupropion, Phentermine-Topiramate, Semaglutide (Wegovy®)
Other · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
25 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Obesity, Colorectal Cancer, Microbial Colonization, Time Restricted Feeding, Stress, Psychological
Interventions
TRE, MBSR
Behavioral
Lead sponsor
Lisa Tussing-Humphreys
Other
Eligibility
18 Years to 39 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Hypertension
Interventions
GOALS, Minding GOALS
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 79 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Overweight Adolescents, Overweight or Obesity, Impulsive Behavior, Overeating
Interventions
Weight loss treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
14 Years to 18 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania