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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: written exposure therapy Clear all
Completed Not applicable Interventional

An Efficient Treatment for Posttraumatic Injury for Firefighters

NCT05950035
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia, Nightmare
Interventions
Written Exposure Therapy (WET), Cognitive Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn), Waitlist
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 28, 2026, 6:53 AM EDT
Recruiting Not applicable Interventional

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer

NCT07636200
View directory record Official record
Conditions
Advanced Solid Tumor Cancer, Stage IV Cancer (Solid Tumors Only), Glioblastoma, Stage III Ovarian Cancer, Small Cell Lung Cancer Extensive Stage
Interventions
Written Exposure-Based Coping Intervention (EASE), Usual Care Control Condition
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 28, 2026, 6:53 AM EDT
Recruiting Not applicable Interventional

rTMS-augmented Written Exposure Therapy for PTSD

NCT05149534
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Written Exposure Therapy, repetitive transcranial magnetic stimulation
Behavioral · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 28, 2026, 6:53 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application

NCT02758990
View directory record Official record
Conditions
Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds, Dyspnea, Headache, Migraine Disorders, Arthritis, Arthralgia, Anxiety, Sleep Initiation and Maintenance Disorders, Sleep Deprivation
Interventions
Vitamin A, Vitamin B6, Vitamin C, Nicotinamide, Vitamin D3, Vitamin E, Broccoli, Spinach, Caffeine, Coffee, Axon Eyewear, Chocolate
Dietary Supplement · Other · Device
Lead sponsor
Verifomics LLC
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2017 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional

Trial of Written Exposure for Metastatic Cancer Patients (EASE)

NCT06042400
View directory record Official record
Conditions
Metastatic Cancer, Solid Tumor Cancer, Lymphoproliferative Disorders, Anxiety, Post-traumatic Stress Symptoms, Fear of Cancer Progression
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial of Treatment for Trauma-Related Nightmares in Active Duty Military Personnel

NCT02506595
View directory record Official record
Conditions
Nightmares
Interventions
ERRT-M for Nightmares
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2019 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness Research in Veterans With PTSD

NCT01928732
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy (CPT), Prolonged Exposure (PE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
916 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
18
States / cities
Tuscaloosa, Alabama • Phoenix, Arizona • Long Beach, California + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional

Empowering Perinatal Adolescents Through Writing

NCT06771817
View directory record Official record
Conditions
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 24 Years · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Written Exposure Therapy for Posttraumatic Stress Disorder

NCT01800773
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Written Exposure Therapy, Cognitive Processing Therapy
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional

Evaluating Supplementing Residential Substance Use Treatment With Written Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD) and Substance Use Disorders (SUD)

NCT05536908
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Residential Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 28, 2026, 6:53 AM EDT
Terminated Not applicable Interventional

Reclaiming Your Life After Sexual Trauma

NCT05268367
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Sexual Assault and Rape
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
Jesse McCann
Other
Eligibility
18 Years to 100 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Written Exposure Therapy to Improve Lives After Stress Exposure

NCT05390775
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Written Exposure Therapy (WISE), Non-emotional Writing
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
6
States / cities
Gainesville, Florida • Indianapolis, Indiana • Worcester, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Phase 4 Interventional Results available

Sequenced Treatment Effectiveness for Posttraumatic Stress

NCT04597190
View directory record Official record
Conditions
PTSD
Interventions
Selective serotonin reuptake inhibitor, Serotonin-norepinephrine reuptake inhibitor, Written Exposure Therapy
Drug · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
15
States / cities
North Little Rock, Arkansas • West Memphis, Arkansas • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise and Therapeutic Exposure

NCT05177458
View directory record Official record
Conditions
PTSD
Interventions
Experimental, Active Control
Behavioral
Lead sponsor
Thomas Adams
Other
Eligibility
21 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 28, 2026, 6:53 AM EDT
Recruiting Not applicable Interventional

Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment

NCT06532773
View directory record Official record
Conditions
Hematologic Malignancy
Interventions
Nite2Day+
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 28, 2026, 6:53 AM EDT
Recruiting Not applicable Interventional

Shared Decision Making in PTSD Treatment

NCT06953687
View directory record Official record
Conditions
Post Traumatic Stress Disorder PTSD
Interventions
Prolonged Exposure Therapy, Cognitive Processing Therapy, Written Exposure Therapy, Shared Decision Making (SHARE)
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Fort Hood, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 28, 2026, 6:53 AM EDT
Terminated Not applicable Interventional Results available

Early Psychological Intervention to Prevent Cardiovascular Event-Induced PTSD (REACH Sub-study)

NCT03605693
View directory record Official record
Conditions
Acute Coronary Syndrome, TIA, Stroke, Cardiac Arrest, PTSD
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional

The Role of Exercise in the Treatment of PTSD Symptoms

NCT02649127
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
imaginal therapy, exercise, self-care
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2017 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Phase 2 Interventional Results available

Adding Trauma-focused Psychotherapy to Ketamine Treatment for Chronic PTSD

NCT04889664
View directory record Official record
Conditions
PTSD
Interventions
Ketamine, Written Exposure Therapy
Drug · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Manhattan, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy

NCT05419999
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Soterix 1x1 tDCS mini CT, Sham Soterix 1x1 tDCS Mini CT, Written Exposure Therapy (WET)
Device · Other · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 28, 2026, 6:53 AM EDT
Recruiting Not applicable Interventional

Written Exposure Therapy for Suicide Prevention

NCT05878795
View directory record Official record
Conditions
Suicide, Attempted, Suicide Threat
Interventions
WET-SP, TAU
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional

Integrated Intervention Post-Sexual Assault

NCT04724746
View directory record Official record
Conditions
Substance Use Disorders, Posttraumatic Stress Disorder, Sexual Assault
Interventions
Written Exposure and Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Sep 28, 2026, 6:53 AM EDT
Recruiting Not applicable Interventional

Written Exposure Therapy for Veterans With SUD and PTSD

NCT05327504
View directory record Official record
Conditions
Substance Use Disorders, Posttraumatic Stress Disorder
Interventions
Written Exposure Therapy, Neutral Topic Writing
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 28, 2026, 6:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Parent Key Opinion Leaders to Increase Demand of Effective Treatments for Youth Anxiety

NCT04929262
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Supporting Anxious Youth: Strategies for Caregivers
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Sep 28, 2026, 6:53 AM EDT