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ClinicalTrials.gov public records Last synced Oct 17, 2026, 12:04 PM EDT

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Showing 217–240 of 1,056 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Medical University of South Carolina Clear all
Completed Not applicable Interventional Results available

Motor-Sparing Peripheral Nerve Blockade Facilitates Mobility Post Total Knee Arthroplasty: A Randomized Controlled Trial

NCT02773537
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
Femoral nerve catheter and sciatic nerve block, Adductor canal catheter and selective tibial block, Adductor canal catheter only
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Oct 17, 2026, 12:04 PM EDT
Recruiting No phase listed Observational

The Heart Outcomes in Pregnancy Expectations for Mom and Baby Study

NCT06517628
View directory record Official record
Conditions
Pregnancy Complications, Cardiovascular
Interventions
Purely observational study on the care and outcomes of participants with cardiovascular disease in pregnancy.
Other
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 20, 2025 · Synced Oct 17, 2026, 12:04 PM EDT
Recruiting Phase 2 Interventional

Phase 2 Study of Fingolimod in Lung Cancers

NCT06424067
View directory record Official record
Conditions
Non Small Cell Lung Cancer, Small-cell Lung Cancer
Interventions
Fingolimod 0.5 milligram (mg) [Gilenya]
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SinuSonic for ETD and Facial Pain: Acoustic Vibration + Oscillating Expiratory Pressure

NCT04404036
View directory record Official record
Conditions
Eustachian Tube Dysfunction, Facial Pain
Interventions
SinuSonic Device
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 17, 2026, 12:04 PM EDT
Recruiting Not applicable Interventional

Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait

NCT06994728
View directory record Official record
Conditions
Parkinson Disease, Gait Disorders, Neurologic, Visuospatial/Perceptual Abilities
Interventions
Left STN-DBS on, right STN-DBS off first, Right STN-DBS on, left STN-DBS off first
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 17, 2026, 12:04 PM EDT
Terminated Not applicable Interventional Results available

Does Perioperative Goal Directed Therapy Using Flotrac Improve Outcomes in Esophagectomy Patients

NCT02864355
View directory record Official record
Conditions
Esophageal Cancer
Interventions
Goal Directed Therapy
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Oct 17, 2026, 12:04 PM EDT
Withdrawn Not applicable Interventional

Evaluating Race Specific AGE Accumulation As a Behavioral Biomarker Prostate Cancer Survivors

NCT03459755
View directory record Official record
Conditions
Prostate Cancer
Interventions
Physical Activity
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
45 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Phase 3 Interventional Results available

Convalescent Plasma in Outpatients With COVID-19

NCT04355767
View directory record Official record
Conditions
Covid19
Interventions
Convalescent Plasma, Saline
Biological
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
511 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
53
States / cities
Chandler, Arizona • Phoenix, Arizona • La Jolla, California + 41 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Oct 17, 2026, 12:04 PM EDT
Terminated Not applicable Interventional

Gemcitabine-Cisplatin-90Y TARE for Unresectable Intrahepatic Cholangiocarcinoma

NCT02512692
View directory record Official record
Conditions
Intrahepatic Cholangiocarcinoma
Interventions
SIR-Spheres microspheres (Yttrium-90 Microspheres), Gemcitabine, Cisplatin
Device · Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 17, 2026, 12:04 PM EDT
Recruiting Not applicable Interventional

Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

NCT03536312
View directory record Official record
Conditions
Ascending Aortic Aneurysm Enlargement, Ascending Aorta Aneurysm
Interventions
Thoracic Aortic Surgery
Procedure
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years to 79 Years
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2035
U.S. locations
16
States / cities
San Francisco, California • Iowa City, Iowa • Boston, Massachusetts + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Phase 2 Interventional Results available

Impact of Lofexidine on Stress, Craving and Opioid Use

NCT03718065
View directory record Official record
Conditions
Opioid-use Disorder, Opiate Dependence
Interventions
Lofexidine, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ESCAPE Kits for Elopement Prevention in Children With Autism

NCT07225907
View directory record Official record
Conditions
Autism Spectrum Disorder, Child Safety, Caregiver Stress
Interventions
Elopement Prevention Kits
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
4 Years to 11 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Phase 1 Interventional Results available

Clinical Trial Intelligent Biometrics for PTSD - Clinical Trial

NCT04471207
View directory record Official record
Conditions
PTSD
Interventions
Therapist Guided Prolonged Exposure with BioWare Device, Record Only Prolonged Exposure with BioWare Device
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Not applicable Interventional Results available

Effect of Oxytocin on Craving and Therapy Response

NCT01827332
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Oxytocin, Saline
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 2, 2017 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Phase 2 Interventional Results available

Oxytocin and Stress Response in Alcohol Use Disorder

NCT03610633
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 40 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2019 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tension Tamer Randomized Control Trial

NCT03168789
View directory record Official record
Conditions
Pre-hypertension
Interventions
Tension Tamer (TT), Lifestyle education program (SPCTL)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Early Phase 1 Interventional

Open Trial of Technology-Enhanced Behavioral Intervention for Buprenorphine Retention in Pregnant and Postpartum People

NCT06496230
View directory record Official record
Conditions
Opioid Use Disorder, Pregnancy Related
Interventions
Empowering Pregnant Women and People Receiving Medications for Opioid Use Disorder
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Phase 4 Interventional Results available

Acamprosate in Alcoholics With Comorbid Anxiety or Depression

NCT00330174
View directory record Official record
Conditions
Alcohol Dependence, Major Depression, Social Anxiety Disorder, Generalized Anxiety Disorder
Interventions
Acamprosate
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
3
States / cities
Belmont, Massachusetts • New York, New York • Pickens, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Not applicable Interventional Results available

Navigation for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC

NCT04098458
View directory record Official record
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
NDURE
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Oct 17, 2026, 12:04 PM EDT
Not listed Phase 3 Interventional

Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation

NCT01212848
View directory record Official record
Conditions
Depressive Episode, Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation - Sham Comparator
Device
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Bethesda, Maryland • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 17, 2026, 12:04 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Sedline 4 Channel Electroencephalogram (EEG) Monitoring During Suppression of Unilateral Hemispheric Function (Wada Test

NCT02503878
View directory record Official record
Conditions
Seizure
Interventions
Masimo Sedline brain function monitors
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 2, 2016 · Synced Oct 17, 2026, 12:04 PM EDT
Recruiting Not applicable Interventional

The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention

NCT06828835
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Reach for Equity in Pediatric Obstructive Sleep Evaluation (REPOSE), Usual Care
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
2 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 17, 2026, 12:04 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gait Mate: Examining Neural Networks Engaged During Lower Extremity Movement in the MRI

NCT03604367
View directory record Official record
Conditions
Stroke, Motor Activity
Interventions
GAITRite assessment
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 17, 2026, 12:04 PM EDT
Completed Not applicable Interventional

COAST: Coiling of Aneurysms Smaller Than 5mm With Hypersoft® and Hydrogel Coils

NCT02259504
View directory record Official record
Conditions
Small Intracranial Aneurysms
Interventions
PHASE 1- HyperSoft® 3D and HyperSoft® Helical Coils, PHASE 2 - HydroSoft® 3D and HydroSoft® Helical Coils
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 25, 2021 · Synced Oct 17, 2026, 12:04 PM EDT