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ClinicalTrials.gov public records Last synced Oct 28, 2026, 12:24 AM EDT

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Showing 265–288 of 3,664 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Mayo Clinic Clear all
Recruiting Not applicable Interventional

Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis

NCT03868592
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Gastric sleeve/bariatric surgery
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Changes in Intestinal Permeability 4 Hours After Gluten Challenge

NCT03288831
View directory record Official record
Conditions
Celiac Disease, Wheat Hypersensitivity, Gluten Sensitivity, Gluten Enteropathy, Immune System and Related Disorders, Duodenal Diseases
Interventions
Gluten, Placebo
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 7, 2019 · Synced Oct 28, 2026, 12:24 AM EDT
Recruiting Not applicable Interventional

Ultrasound Microvessel Imaging for the Evaluation of Ovarian and Adnexal Lesions

NCT07280312
View directory record Official record
Conditions
Female Reproductive System Adnexal Neoplasm, Ovarian Carcinoma, Female Reproductive System Neoplasm, Ovarian Neoplasms, Adnexal Lesion, Ovarian Lesion
Interventions
Transvaginal Ultrasound, Ultrasound Microvessel Imaging
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Completed No phase listed Observational

Myocardial Injury in Patients With Cardiac Implantable Electronic Devices Following Magnetic Resonance Imaging

NCT04151953
View directory record Official record
Conditions
Magnetic Resonance Imaging (MRI)
Interventions
Blood sample collection
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Oct 28, 2026, 12:24 AM EDT
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies

NCT04258631
View directory record Official record
Conditions
Malignant Female Reproductive System Neoplasm
Interventions
Hydromorphone, Laparotomy, Liposomal Bupivacaine, Questionnaire Administration
Drug · Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 28, 2026, 12:24 AM EDT
Completed Phase 2 Interventional Results available

The Impact of Velcade(TM)on Antibody Secreting Cells in Sensitized Renal Allograft Candidates

NCT00722722
View directory record Official record
Conditions
Kidney Transplantation
Interventions
Bortezomib
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 9, 2016 · Synced Oct 28, 2026, 12:24 AM EDT
Terminated No phase listed Observational

Evaluation of Autonomic Function in Individuals With Cornelia de Lange Syndrome (CdLS)

NCT03113877
View directory record Official record
Conditions
Cornelia de Lange Syndrome
Interventions
Autonomic Dysfunction Testing
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
8 Years to 18 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 6, 2018 · Synced Oct 28, 2026, 12:24 AM EDT
Recruiting Not applicable Interventional

The PeriCut Catheter System Early Feasibility Study (REIMAGINE-HFpEF)

NCT06702501
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
PeriCut Catheter System performs minimally invasive pericardiotomy
Device
Lead sponsor
Heart Failure Solutions, Inc.
Industry
Eligibility
30 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 28, 2026, 12:24 AM EDT
Completed Phase 2 Interventional Results available

Topical Composition Therapy (2013-MCN-333) for the Treatment of Melasma

NCT02730819
View directory record Official record
Conditions
Melasma
Interventions
Illuminate Cream
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 20, 2017 · Synced Oct 28, 2026, 12:24 AM EDT
Recruiting Not applicable Interventional

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

NCT02958462
View directory record Official record
Conditions
Myeloid Malignancy, Inherited Bone Marrow Failure Syndrome, Clonal Expansion, Cytopenia, Bone Marrow Failure Syndrome, Clonal Cytopenia of Undetermined Significance, Clonal Hematopoiesis of Indeterminate Potential, Hematologic Neoplasms, Hematopoietic and Lymphatic System Neoplasm, Hereditary Neoplastic Syndrome, Idiopathic Cytopenia of Undetermined Significance, Idiopathic Dysplasia of Uncertain Significance, Low Risk Myelodysplastic Syndrome
Interventions
Biospecimen Collection, Bone Marrow Biopsy, Punch Biopsy, Buccal Swab, Clinical Evaluation, Genetic Counseling, Quality-of-Life Assessment, Electronic Health Record Review
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2035
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Recruiting No phase listed Observational

A Multicenter Study in Bronchoscopy Combining Stimulated Raman Histology With Artificial Intelligence for Rapid Lung Cancer Detection - The ON-SITE Study

NCT07045103
View directory record Official record
Conditions
Lung Biopsy
Interventions
Not listed
Lead sponsor
Invenio Imaging Inc.
Industry
Eligibility
22 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
San Diego, California • Jacksonville, Florida • Grand Rapids, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 28, 2026, 12:24 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Group Meaning-Centered Psychotherapy for the Improvement of Wellbeing in Caregivers of Patients With Serious Illness

NCT06630351
View directory record Official record
Conditions
Advanced Malignant Solid Neoplasm
Interventions
Behavioral Counseling, Discussion, Health Promotion and Education, Interview, Questionnaire Administration
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Insulin Deprivation on Brain Structure and Function in Humans With Type 1 Diabetes

NCT03392441
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Diabetes, Diabetes Complications
Interventions
Insulin Deprivation in Type 1 Diabetic Patients
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
14 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Oct 28, 2026, 12:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Magnetic Resonance Elastography of Myofascial Pain Syndrome

NCT05604066
View directory record Official record
Conditions
Myofascial Pain
Interventions
Magnetic Resonance (MR) Elastography, MRI structural imaging
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Terminated Phase 3 Interventional Results available

Aspirin for Treatment of Multiple Sclerosis-Related Fatigue

NCT00467584
View directory record Official record
Conditions
Multiple Sclerosis, Fatigue
Interventions
High Dose Aspirin (1300 mg/day), Low Dose Aspirin (162 mg/day), Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 28, 2026, 12:24 AM EDT
Completed Phase 2 Interventional Results available

Vidofludimus Calcium for Primary Sclerosing Cholangitis

NCT03722576
View directory record Official record
Conditions
Primary Sclerosing Cholangitis
Interventions
Vidofludimus calcium
Drug
Lead sponsor
Elizabeth Carey
Other
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Phoenix, Arizona • Tempe, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Oct 28, 2026, 12:24 AM EDT
Recruiting Phase 2 Interventional

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

NCT07639359
View directory record Official record
Conditions
Critical Illness, Depressive Symptoms
Interventions
Ketamine (0.5 mg/kg), Normal Saline (0.9% NaCl)
Drug · Other
Lead sponsor
Hospital Italiano de Buenos Aires
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Withdrawn Not applicable Interventional

Estrogen Receptor Expression in Breast Cancer - Assessed With Positron Emission Mammography

NCT03266562
View directory record Official record
Conditions
Breast Neoplasm
Interventions
F-18 FES, F-18 FDG
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 90 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Oct 28, 2026, 12:24 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Normative Values for Cognitive Testing and Alzheimer's Imaging Biomarkers in Young Adults

NCT01609335
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
F-18 FDG, C-11 PiB
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 49 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 8, 2014 · Synced Oct 28, 2026, 12:24 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor

NCT00385450
View directory record Official record
Conditions
Cardiopulmonary Bypass
Interventions
Nelfinavir/placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 28, 2026, 12:24 AM EDT
No Longer Available No phase listed Expanded access

Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS

NCT06743776
View directory record Official record
Conditions
ALS
Interventions
MN-166
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
U.S. locations
15
States / cities
Scottsdale, Arizona • Orange, California • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Active, not recruiting Not applicable Interventional

Neurophysiologically Based Brain State Tracking and Modulation in Focal Epilepsy

NCT03946618
View directory record Official record
Conditions
Epilepsy
Interventions
Medtronic Summit System, Olympus
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Mixed-Methods Evaluation of Short-, Medium-, and Long-Term Outcomes Following Hip Treatment

NCT06891196
View directory record Official record
Conditions
Hip Dysplasia, Legg-Calvâe-Perthes Disease, Avascular Necrosis of Hip
Interventions
Long-term Follow-up Surveys
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 28, 2026, 12:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Hypersensitivity Reactions During Anesthesia

NCT04125420
View directory record Official record
Conditions
Allergy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
940 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 28, 2026, 12:24 AM EDT