Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 1, 2026, 11:06 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Aphakia, Postcataract
Interventions
Clareon Vivity and Clareon Vivity Toric IOLs targeted for mini-monovision with dominant eye set at emmetropia and non-dominant eye at -0.50.
Device
Lead sponsor
Debbie S. Kuo, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Glaucoma
Interventions
Travoprost 0.004%/timolol maleate 0.5% fixed combination
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Total30 For Contact Lens Dropouts

NCT06967298
Conditions
Dry Eye, Contact Lens Complication, Contact Lenses
Interventions
T30 Contact lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Photorefractive Keratectomy
Interventions
nepafenac 0.1%, ketorolac 0.4%
Drug · Other
Lead sponsor
Alcon Research
Industry
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Ocular Hypertension, Open Angle Glaucoma
Interventions
Netarsudil 0.01%/latanoprost 0.005% ophthalmic solution, Netarsudil 0.02%/latanoprost 0.005% ophthalmic solution
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
489 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
30
States / cities
Dothan, Alabama • Phoenix, Arizona • Garden Grove, California + 25 more
Conditions
Bacterial Conjunctivitis
Interventions
Moxifloxacin Alternative Formulation Ophthalmic Solution 0.5%, Moxifloxacin hydrochloride ophthalmic solution 0.5% as base
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
1 Month and older
Enrollment
695 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Refractive Errors, Ametropia
Interventions
Lehfilcon A contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses, Hydrogen peroxide-based cleaning and disinfecting solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Longwood, Florida • Maitland, Florida • Warwick, Rhode Island + 1 more
Conditions
Glaucoma, Open-Angle, Ocular Hypertension
Interventions
Travoprost, Latanoprost
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
14
States / cities
Los Angeles, California • Novato, California • Oakland, California + 10 more
Conditions
Dry Eye
Interventions
Systane Free Lubricant Eye Drops
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
El Paso, Texas
Completed Phase 4 Interventional Accepts healthy volunteers

The Evaluation of Balanced Salt Solution During Cataract Surgery

NCT05853978
Conditions
Fuchs Dystrophy, Cataract
Interventions
BSS Plus, BSS
Drug
Lead sponsor
Adam Fedyk, MD, FACS
Other
Eligibility
22 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Town and Country, Missouri
Conditions
Bacterial Conjunctivitis
Interventions
quinolone
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
1 Month and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Chronic Central Serous Chorioretinopathy
Interventions
Anecortave Acetate Sterile suspension 15 mg, Anecortave Acetate
Drug
Lead sponsor
Manhattan Eye, Ear & Throat Hospital
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
2
States / cities
New York, New York
Not yet recruiting Phase 4 Interventional

Rocklatan Retinal Perfusion OCT Study

NCT07174401
Conditions
Glaucoma
Interventions
Rocklatan eye drops will be instilled nightly in one eye diagnosed with glaucoma for up to 12 months., Two optical coherence tomography (OCT) devices will be used to assess blood flow changes.
Drug · Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Completed Not applicable Interventional Results available

Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs

NCT03733730
Conditions
Aphakia, Presbyopia, Astigmatism
Interventions
ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
2,449 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
37
States / cities
Dothan, Alabama • Phoenix, Arizona • Fresno, California + 32 more
Conditions
Open-Angle Glaucoma, Ocular Hypertension
Interventions
Xalatan
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more
Conditions
Cataract
Interventions
AcrySof IQ PanOptix Multifocal IOL, AcrySof Monofocal IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
12
States / cities
Fresno, California • Mt. Dora, Florida • Panama City, Florida + 9 more
Conditions
Myopia, Hyperopia, Presbyopia, Astigmatism
Interventions
Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
7 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
San Diego, California • Ponte Vedra Beach, Florida • West Palm Beach, Florida + 8 more
Conditions
Vasomotor Rhinitis
Interventions
Olopatadine HCL (Patanase) Nasal Spray, 0.6%, Azelastine HCl (Astelin) Nasal Spray, 137 mcg
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
12 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Myopia
Interventions
WaveLight EX500 excimer laser system with InnovEyes sightmap, LASIK, InnovEyes sightmap
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
9
States / cities
San Diego, California • Indianapolis, Indiana • Chevy Chase, Maryland + 6 more
Completed No phase listed Observational

Hydrus Learning Curve Study

NCT06964139
Conditions
Surgery, Surgical Procedures, Minimally Invasive, Training, Training Effectiveness, Learning Curve
Interventions
Surgical video grading
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
5 participants
Timeline
2024 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed No phase listed Observational Accepts healthy volunteers

Visual Performance of Bilateral AcrySof ReSTOR Aspheric +4

NCT01215045
Conditions
Cataract
Interventions
AcrySof ReSTOR Aspheric +4
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Presbyopia
Interventions
Serafilcon A multifocal contact lenses, Senofilcon A multifocal contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
8
States / cities
Los Angeles, California • Oakland, California • Maitland, Florida + 5 more