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Showing 25–48 of 397 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

DD T2 Daily Disposable Registration Trial

NCT03305770
Conditions
Myopia, Refractive Errors
Interventions
verofilcon A contact lenses, delefilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
6
States / cities
San Diego, California • Longwood, Florida • Maitland, Florida + 3 more
Completed Not applicable Interventional Results available

Evaluation of Delefilcon A Contact Lenses

NCT06884202
Conditions
Refractive Errors, Myopia
Interventions
Delefilcon A contact lenses with different base curves and diameters, Delefilcon A contact lenses with standard base curves and diameters
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
16
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 13 more
Conditions
Refractive Ametropia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Conditions
Aphakia
Interventions
AcrySof single-piece IOL, AcrySof multi-piece IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
Not listed
Enrollment
138 participants
Timeline
2023 – 2025
U.S. locations
6
States / cities
Burbank, California • Jacksonville, Florida • Rock Island, Illinois + 3 more
Conditions
Visual Outcomes
Interventions
Acrysof ReSTOR multifocal IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Allergic Conjunctivitis
Interventions
Olopatadine hydrochloride ophthalmic solution, 0.2%
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Contact Lens Solution Toxicity
Interventions
PureVision lenses soaked in ReNu Multiplus, PureVision lenses soaked in OptiFree RePlenish
Device
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Fullerton, California
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Visual Function After Implantation of Bilateral AcrySof ReSTOR Aspheric +3

NCT00719732
Conditions
Cataract
Interventions
ReSTOR
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 70 Years
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Accepts healthy volunteers

T30 for Astigmatism in Digital Device Users

NCT06266728
Conditions
Contact Lens Complication, Astigmatism, Refractive Errors
Interventions
Total30 for Astigmatism Contact Lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
2
States / cities
Pittsburg, Kansas • Coldwater, Mississippi
Withdrawn Not applicable Interventional

UNITY VCS Vitreoretinal Surgery

NCT07054281
Conditions
Epiretinal Membrane, Macular Hole, Visually Significant Vitreous Floater, Vitreomacular Traction, Vitreous Hemorrhage, Proliferative Diabetic Retinopathy, Rhegmatogenous Retinal Detachment, Retained Lens Material in the Posterior Segment
Interventions
UNITY Vitreoretinal Cataract System (VCS), CONSTELLATION Vision System, Vitreoretinal ophthalmic surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
8
States / cities
Scottsdale, Arizona • Laguna Hills, California • West Des Moines, Iowa + 5 more
Completed Not applicable Interventional Results available

Long Term Safety Protocol for the AcrySof CACHET Phakic Lens

NCT01497067
Conditions
Myopia
Interventions
ACRYSOF CACHET Phakic Lens (L-series)
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
657 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Uveitis, Posterior, Glaucoma
Interventions
anecortave acetate
Drug
Lead sponsor
Texas Retina Associates
Other
Eligibility
10 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Arlington, Texas
Completed Not applicable Interventional Results available

Comparison of Two Daily Disposable Lenses

NCT04013789
Conditions
Refractive Ametropia, Myopia
Interventions
DACP FreshTech contact lenses, DACP contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 35 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Digital Device Users Who Are Treated With Systane Hydration PF

NCT04837807
Conditions
Dry Eye
Interventions
Systane Hydration PF
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Eye Diseases
Interventions
Anecortave Acetate Sterile Suspension, 6 mg/mL, Anecortave Acetate Suspension Depot, 30 mg/mL, Anecortave Acetate Sterile Suspension, 60 mg/mL, Anecortave Acetate Vehicle
Drug · Other
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
5
States / cities
Jacksonville, Florida • Miami, Florida • Detroit, Michigan + 2 more
Conditions
Glaucoma, Ocular Hypertension
Interventions
Netarsudil Ophthalmic Solution (Rhopressa), Artificial Tears (AT)
Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Bloomington, Indiana
Completed No phase listed Observational

EX-PRESS® P-50 and EX-PRESS® P-200

NCT06119178
Conditions
Glaucoma
Interventions
EX-PRESS P-50 filtration device, EX-PRESS P-200 filtration device
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Rogers, Arkansas • El Paso, Texas
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more
Conditions
Dry Eye Syndromes, Keratoconjunctivitis Sicca, Lacrimal Apparatus Diseases, Keratoconjunctivitis, Eye Diseases, Keratitis, Corneal Disease, Ophthalmic Solution
Interventions
Systane Complete, Systane Ultra
Other
Lead sponsor
Ohio State University
Other
Eligibility
30 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wear Experience With Daily Toric Contact Lenses Over a Long Day

NCT04844281
Conditions
Contact Lens, Astigmatism of Both Eyes
Interventions
Precision1® Daily Disposable Toric Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Results available

Clinical Biocompatibility Evaluation of Contact Lens Coatings

NCT03034928
Conditions
Refractive Errors, Ametropia
Interventions
Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS, Contact lens with investigational coating 2
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Johns Creek, Georgia
Conditions
Open-angle Glaucoma, Ocular Hypertension
Interventions
Brinzolamide/Timolol
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Aphakia, Postcataract
Interventions
Clareon Vivity and Clareon Vivity Toric IOLs targeted for mini-monovision with dominant eye set at emmetropia and non-dominant eye at -0.50.
Device
Lead sponsor
Debbie S. Kuo, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Dry Eye, Contact Lens Complication
Interventions
Systane Complete, Sensitive Eyes Rewetting Drops
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
3
States / cities
Birmingham, Alabama • Babylon, New York • Memphis, Tennessee