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ClinicalTrials.gov public records Last synced Oct 8, 2026, 12:53 PM EDT

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Showing 25–48 of 108 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Canadian Institutes of Health Research (CIHR) Clear all
Active, not recruiting Phase 3 Interventional

Adolescent Type 1 Diabetes Treatment With SGLT2i for hyperglycEMia & hyPerfilTration Trial

NCT04333823
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Dapagliflozin 5mg, Placebo
Drug
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
12 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Phase 4 Interventional Results available

Clinical Trial for the Prevention of Vasovagal Syncope

NCT00118482
View directory record Official record
Conditions
Syncope, Vasovagal, Neurally-Mediated
Interventions
fludrocortisone acetate
Drug
Lead sponsor
University of Calgary
Other
Eligibility
14 Years and older
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
3
States / cities
Boston, Massachusetts • Nashville, Tennessee • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Not applicable Interventional Results available

Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation

NCT00806988
View directory record Official record
Conditions
Mitral Valve Insufficiency, Coronary Artery Disease
Interventions
Mitral Valve Repair, CABG
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
19
States / cities
Los Angeles, California • Atlanta, Georgia • Marietta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Not applicable Interventional Results available

Using Alternative Implants for the Surgical Treatment of Hip Fractures (The FAITH Study)

NCT00761813
View directory record Official record
Conditions
Femoral Neck Fractures
Interventions
Open reduction internal fixation (ORIF) with single sliding hip screw, ORIF with multiple cancellous screws
Device
Lead sponsor
University of Minnesota
Other
Eligibility
50 Years and older
Enrollment
1,108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
32
States / cities
Birmingham, Alabama • Irvine, California • Orange, California + 28 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2018 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Phase 2 Interventional Results available

Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation

NCT00807040
View directory record Official record
Conditions
Mitral Valve Insufficiency, Coronary Artery Disease
Interventions
Mitral Valve Repair with Annuloplasty, Mitral Valve Replacement
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
18
States / cities
Los Angeles, California • Atlanta, Georgia • Marietta, Georgia + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2019 · Synced Oct 8, 2026, 12:53 PM EDT
Completed No phase listed Observational

Weaning And Variability Evaluation

NCT01237886
View directory record Official record
Conditions
Mechanically Ventilated Patients, Extubation
Interventions
Not listed
Lead sponsor
Ottawa Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
7
States / cities
Ann Arbor, Michigan • Billings, Montana • Lebanon, New Hampshire + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 8, 2026, 12:53 PM EDT
Not listed Not applicable Interventional

CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients

NCT03471247
View directory record Official record
Conditions
Intensive Care Unit Acquired Weakness, Critical Care, Mechanical Ventilation, Respiratory Failure
Interventions
In-Bed Cycle Ergometer, Routine PT
Device · Other
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 8, 2026, 12:53 PM EDT
Not listed Not applicable Interventional

Use of Semen TEX101 to Improve Sperm Retrieval Rates for Men With Non-obstructive Azoospermia

NCT02851966
View directory record Official record
Conditions
Non-obstructive Azoospermia
Interventions
mTESE
Procedure
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
San Francisco, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Not applicable Interventional

Glioma Supra Marginal Incision Trial

NCT04737577
View directory record Official record
Conditions
High Grade Glioma
Interventions
Supramarginal resection, Conventional (i.e. GTR) resection
Procedure
Lead sponsor
Sunnybrook Health Sciences Centre
Other
Eligibility
18 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 8, 2026, 12:53 PM EDT
Terminated Phase 3 Interventional Results available

Hypertonic Resuscitation Following Severe Traumatic Brain Injury (TBI)

NCT00316004
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
7.5% Hypertonic Saline in 6% Dextran-70 (HSD), 7.5% Hypertonic Saline (HS), 0.9% Normal Saline (NS)
Drug
Lead sponsor
University of Washington
Other
Eligibility
15 Years and older
Enrollment
1,331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
10
States / cities
Birmingham, Alabama • Orange, California • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated May 19, 2011 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hockey Fans in Training (Hockey FIT): Improving Men's Health Through the Power of Sport

NCT03636282
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Hockey FIT Program (Immediate Delivery)
Behavioral
Lead sponsor
Western University, Canada
Other
Eligibility
35 Years to 65 Years · Male only
Enrollment
997 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
3
States / cities
Flint, Michigan • Saginaw, Michigan • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 7, 2023 · Synced Oct 8, 2026, 12:53 PM EDT
Terminated Not applicable Interventional Results available

Trial on Endovascular Aneurysm Management

NCT00537134
View directory record Official record
Conditions
Brain Aneurysm
Interventions
Embolization, coiling
Device
Lead sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
6
States / cities
Phoenix, Arizona • Boston, Massachusetts • Brooklyn, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 30, 2022 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Phase 3 Interventional

PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT)

NCT00182143
View directory record Official record
Conditions
Critical Illness, Deep Venous Thrombosis
Interventions
LMWH (Fragmin, dalteparin), Unfractionated Heparin
Drug
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
3,659 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
4
States / cities
Rochester, Minnesota • St Louis, Missouri • Providence, Rhode Island + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2011 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Phase 3 Interventional

Premature Infants in Need of Transfusion (PINT)

NCT00182390
View directory record Official record
Conditions
Anemia of Prematurity
Interventions
Red blood cell transfusion
Procedure
Lead sponsor
McMaster University
Other
Eligibility
Up to 48 Hours
Enrollment
424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
2
States / cities
Albany, New York • Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Not applicable Interventional

Transfusion Requirements in Cardiac Surgery

NCT01484639
View directory record Official record
Conditions
Cardiac Surgery
Interventions
Liberal transfusion triggers, Restrictive transfusion triggers
Other
Lead sponsor
Nadine Shehata
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2013 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Pilot Randomized Controlled Trial of Repeated Hands-and-Knees Positioning During Labour

NCT01720004
View directory record Official record
Conditions
Pregnancy, Childbirth and the Puerperium
Interventions
Repeated hands-and-knees positioning during labour
Other
Lead sponsor
University of Toronto
Other
Eligibility
Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2012 · Synced Oct 8, 2026, 12:53 PM EDT
Terminated Phase 2 Interventional

Heparin Anticoagulation in Septic Shock

NCT03378466
View directory record Official record
Conditions
Septic Shock, Vasodilatory Shock
Interventions
Unfractionated heparin, Venous thromboprophylaxis (VTE)
Drug · Other
Lead sponsor
University of Manitoba
Other
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Oct 8, 2026, 12:53 PM EDT
Recruiting Phase 3 Interventional

Simple Bone Cysts in Kids

NCT02193841
View directory record Official record
Conditions
Bone Cyst
Interventions
Curettage with puncture (C & P), Curette, Vitoss morsels
Procedure · Device
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
2 Years to 21 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
11
States / cities
Birmingham, Alabama • Loma Linda, California • Wilmington, Delaware + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Aerosol Box Use on Healthcare Provider Contamination

NCT04880668
View directory record Official record
Conditions
Coronavirus, Covid19, COVID-19 Acute Respiratory Distress Syndrome
Interventions
Aerosol Box (Splashguard)
Device
Lead sponsor
KidSIM Simulation Program
Network
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 8, 2026, 12:53 PM EDT
Terminated Phase 1Phase 2 Interventional

Tamoxifen Therapy for Myotubular Myopathy

NCT04915846
View directory record Official record
Conditions
X Linked Myotubular Myopathy
Interventions
ApoTamox 10mg, Placebo
Drug
Lead sponsor
James Dowling
Other
Eligibility
6 Months and older · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 8, 2026, 12:53 PM EDT
Recruiting Phase 3 Interventional

AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

NCT05848713
View directory record Official record
Conditions
Community-acquired Pneumonia
Interventions
Heparin
Drug
Lead sponsor
University of Manitoba
Other
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
6
States / cities
Chicago, Illinois • Jefferson, Louisiana • Portland, Maine + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Not applicable Interventional Results available

TRIGR - Primary Prevention Study for Type 1 Diabetes in Children at Risk

NCT00179777
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Hydrolysed infant formula, Nonhydrolysed infant formula
Dietary Supplement
Lead sponsor
University of Helsinki
Other
Eligibility
Up to 7 Days
Enrollment
5,156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2017
U.S. locations
2
States / cities
Tampa, Florida • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2021 · Synced Oct 8, 2026, 12:53 PM EDT
Recruiting Not applicable Interventional

Careful Ventilation in Acute Respiratory Distress Syndrome (COVID-19 and Non-COVID-19)

NCT03963622
View directory record Official record
Conditions
ARDS
Interventions
Respiratory Mechanics, Standard Ventilation Strategy
Other
Lead sponsor
Unity Health Toronto
Other
Eligibility
18 Years and older
Enrollment
740 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 8, 2026, 12:53 PM EDT
Completed Phase 3 Interventional

Prospective Randomized Clinical Trial of Fetal Atrial Flutter & Supraventricular Tachycardia Therapy (FAST RCT)

NCT02624765
View directory record Official record
Conditions
Fetal Atrial Flutter Without Hydrops, Fetal Supraventricular Tachycardia Without Hydrops, Fetal Supraventricular Tachycardia With Hydrops
Interventions
Digoxin (monotherapy), Sotalol (monotherapy), Flecainide (monotherapy), Digoxin (dual therapy), Sotalol (dual therapy), Flecainide (dual therapy)
Drug
Lead sponsor
Edgar Jaeggi
Other
Eligibility
16 Years to 50 Years · Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
12
States / cities
San Francisco, California • Aurora, Colorado • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 8, 2026, 12:53 PM EDT