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ClinicalTrials.gov public records Last synced Oct 9, 2026, 4:01 AM EDT

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Showing 25–48 of 839 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Children's Hospital Medical Center, Cincinnati Clear all
Completed Phase 1 Interventional

A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

NCT03355794
View directory record Official record
Conditions
Diffuse Intrinsic Pontine Glioma, Malignant Glioma of Brain, High Grade Glioma, Bithalamic High Grade Glioma, Brainstem Glioma, Glioblastoma, Anaplastic Astrocytoma
Interventions
ribociclib, Everolimus
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Months to 30 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Charlotte, North Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2023 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Not applicable Interventional

Mindful Awareness Practices for ADHD Pilot Open Trial

NCT05584475
View directory record Official record
Conditions
ADHD
Interventions
Mindful Awareness Practices (MAPs)
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 17 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 9, 2026, 4:01 AM EDT
Recruiting No phase listed Observational

MRI Biomarkers in as Predictor of Clinical Endpoints in Pediatric Autoimmune Liver Disease

NCT03178630
View directory record Official record
Conditions
Autoimmune Liver Disease, Autoimmune Hepatitis, Primary Sclerosing Cholangitis
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 23 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2031
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 9, 2026, 4:01 AM EDT
Completed No phase listed Observational

Increased Liver Stiffness: A Study of Acoustic Radiation Force Impulse (ARFI) Elastography

NCT03382119
View directory record Official record
Conditions
Liver Fibroses
Interventions
Ultrasound with ARFI (acoustic radiation force impulse), Ultrasound with backscatter imaging
Device
Lead sponsor
University of Michigan
Other
Eligibility
2 Years to 5 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1

NCT04481035
View directory record Official record
Conditions
Neurofibromatosis 1
Interventions
N-acetylcysteine (NAC), Placebo
Drug · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years to 16 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 9, 2026, 4:01 AM EDT
Completed No phase listed Observational

Registry for Eosinophilic Gastrointestinal Disorders (REGID)

NCT01382563
View directory record Official record
Conditions
Eosinophilic Gastrointestinal Disorders (EGID), Eosinophilic Esophagitis, Eosinophilic Disorder
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Year to 12 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
8
States / cities
San Diego, California • Aurora, Colorado • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 9, 2026, 4:01 AM EDT
Withdrawn Phase 2 Interventional

Liq-NOL Efficacy in Pediatric Patients With Down Syndrome

NCT00891917
View directory record Official record
Conditions
Down Syndrome
Interventions
Ubiquinol-10 Syrup, syrup (placebo)
Dietary Supplement
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 16 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improvised Explosive Device (IED) Level Blasting of Human Blood With Slosh Prevention

NCT03018548
View directory record Official record
Conditions
Brain Injuries
Interventions
blood draw
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Phase 4 Interventional Results available

The Effects of ADHD Medication (TEAM) Study

NCT02293655
View directory record Official record
Conditions
ADHD
Interventions
OROS-Methylphenidate (MPH)
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 11 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Cincinnati, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Phase 1 Interventional

A Proof-of-Concept Study of Minocycline in Autism

NCT04031755
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism
Interventions
Minocycline, Placebos
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 22 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Columbia, Missouri • Cincinnati, Ohio • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 8, 2020 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hearing Aid Noise Reduction in Pediatric Users Pilot Study (Oticon Pilot Study)

NCT04469946
View directory record Official record
Conditions
Hearing Impairment, Sensorineural Hearing Loss, Bilateral
Interventions
Oticon OpenSound Navigator speech enhancement algorithm
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 12 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Phase 2 Interventional Results available

Inhaled Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in Hereditary Pulmonary Alveolar Proteinosis (PAP)

NCT01511068
View directory record Official record
Conditions
Hereditary Pulmonary Alveolar Proteinosis
Interventions
Leukine
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Cincinnati, Ohio • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 9, 2026, 4:01 AM EDT
Active, not recruiting No phase listed Observational

Personalizing Perioperative Analgesia in Children

NCT01140724
View directory record Official record
Conditions
Postoperative Pain
Interventions
Not listed
Lead sponsor
Senthil Sadhasivam
Other
Eligibility
3 Years to 15 Years
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Phase 2 Interventional Results available

Triptorelin for Ovary Protection in Childhood Onset Lupus

NCT00124514
View directory record Official record
Conditions
Systemic Lupus Erythematosus
Interventions
Triptorelin Pamoate, placebo
Drug · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
9 Years to 21 Years · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
9
States / cities
Los Angeles, California • Chicago, Illinois • Hackensack, New Jersey + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 9, 2026, 4:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Prenatal Genetic Diagnosis by Genomic Sequencing

NCT03936101
View directory record Official record
Conditions
Fetal Structural Anomalies
Interventions
Prenatal Genomic Sequencing
Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
1,097 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
5
States / cities
New York, New York • Chapel Hill, North Carolina • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 9, 2026, 4:01 AM EDT
Recruiting Phase 2 Interventional

Trial of Scheduled Versus Treatment Administration of Donor-Derived Viral Specific T-cells for Viral Infections After Stem Cell Transplant

NCT04230356
View directory record Official record
Conditions
Allogeneic Stell Cell Transplant, Viral Infection
Interventions
Viral Specific T-cells (VSTs) Scheduled, Viral Specific T-cells (VSTs) Treatment
Biological
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 9, 2026, 4:01 AM EDT
Completed No phase listed Observational

Milrinone Pharmacokinetics and Acute Kidney Injury

NCT01966237
View directory record Official record
Conditions
Congenital Heart Disease, Acute Kidney Injury
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day to 1 Year
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Q-collar and Brain Injury Biomarkers

NCT02271451
View directory record Official record
Conditions
Concussion
Interventions
Q collar
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
14 Years to 19 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2020 · Synced Oct 9, 2026, 4:01 AM EDT
Completed No phase listed Observational

Registry for HF20 for Pediatric CRRT Under Emergency Use Authorization

NCT04836026
View directory record Official record
Conditions
Pediatric Kidney Disease, Acute Kidney Injury
Interventions
HF20™
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Palo Alto, California • Cincinnati, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Not applicable Interventional Results available

Repetitive Transcranial Magnetic Stimulation to Reduce Tics

NCT01258790
View directory record Official record
Conditions
Tourette Syndrome
Interventions
Sham Repetitive Transcranial Magnetic Stimulation, Active Repetitive Transcranial Magnetic Stimulation
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2014 · Synced Oct 9, 2026, 4:01 AM EDT
Completed No phase listed Observational Results available

Pediatric Aggression and Violence

NCT01253343
View directory record Official record
Conditions
Pediatric Aggression and Violence
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 9 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2013 · Synced Oct 9, 2026, 4:01 AM EDT
Completed Not applicable Interventional

Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke

NCT02489708
View directory record Official record
Conditions
Asthma, Smoking Cessation
Interventions
Cessation Counseling
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Oct 9, 2026, 4:01 AM EDT
Recruiting No phase listed Observational

A National Registry For Pulmonary Alveolar Proteinosis

NCT02461615
View directory record Official record
Conditions
Pulmonary Alveolar Proteinosis
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2030
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 9, 2026, 4:01 AM EDT
Completed No phase listed Observational

Development of PK/PD Model for Individualized Propofol Dosing

NCT00948597
View directory record Official record
Conditions
Obesity, Elective Surgery
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 18 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2014 · Synced Oct 9, 2026, 4:01 AM EDT