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ClinicalTrials.gov public records Last synced Oct 3, 2026, 12:36 PM EDT

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Showing 25–48 of 2,709 matching trials from the live ClinicalTrials.gov search.
Conditions
Juvenile Idiopathic Arthritis
Interventions
Abatacept Injection, Usual Care
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
2 Years to 16 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
19
States / cities
San Francisco, California • Aurora, Colorado • Gainesville, Florida + 16 more
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Autologous Umbilical Cord Blood
Biological
Lead sponsor
Michael Cotten
Other
Eligibility
Up to 2 Days
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Metastatic Breast Cancer
Interventions
Abraxane, Carboplatin
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Lung Cancer
Interventions
Endobronchial ultrasound with transbronchial needle aspiration, Bronchoscopy, Cryobiopsy
Procedure
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Coronary Occlusions
Interventions
Cypher sirolimus eluting coronary stent
Device
Lead sponsor
Sunil Rao
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
13
States / cities
La Jolla, California • Washington D.C., District of Columbia • Atlanta, Georgia + 8 more
Conditions
Urinary Incontinence, Urge
Interventions
InterStim® device, Botox® injection
Device · Drug
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
9
States / cities
Birmingham, Alabama • La Jolla, California • Albuquerque, New Mexico + 6 more
Completed Phase 1Phase 2 Interventional

PK/PD of Digoxin in Infants With SVHD

NCT06613477
Conditions
Single-ventricle, Infant Conditions, Infant, Newborn, Diseases, Infant, Premature, Diseases
Interventions
PK/PD Model Based Dosing of Digoxin in Infants with Single Ventricle Heart Disease
Drug
Lead sponsor
Duke University
Other
Eligibility
30 Days to 6 Months
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Durham, North Carolina • Charleston, South Carolina
Conditions
Preterm Birth
Interventions
Facebook discussions and Virtual group meetings
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Laparoscopic Colorectal Resection
Interventions
TAP block, Epidural, Paravertebral block, Acetaminophen 1g IV, Dexamethasone 4mg, Midazolam up to 2mg, Propofol 1-2.5 mg/kg, Sevoflurane to keep a bispectral index of between 40-60, Local infiltration with 10 mL of plain ropivacaine 0.25%, Lidocaine, Epinephrine, Hydromorphone
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Parent Treatment for Child Social Adjustment

NCT01765166
Conditions
Interpersonal Relations
Interventions
SSGRIN-Parent Guide
Behavioral
Lead sponsor
Duke University
Other
Eligibility
8 Years to 12 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Cary, North Carolina • Durham, North Carolina
Terminated Phase 2 Interventional Results available

Panitumumab and Irinotecan for Malignant Gliomas

NCT01017653
Conditions
Malignant Glioma of Brain
Interventions
Irinotecan, Panitumumab
Drug
Lead sponsor
Annick Desjardins
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional

Palliative Care For Me (PCforMe)

NCT03874195
Conditions
Palliative Care
Interventions
Access to PCforMe for review, Access to three nationally-recognized Palliative Care websites for review
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Sarcoidosis
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
27,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2032
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Covid19
Interventions
COVID-19 Testing
Other
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
4,733 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance

NCT06619405
Conditions
Age-Related Macular Degeneration
Interventions
Streetlab VR
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
50 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Adenosine Deaminase Deficiency, ADA-SCID
Interventions
Lentiviral Gene Transfer
Genetic
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
1 Year to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Genomic Medicine Risk Assessment Care for Everyone - Implementation Phase

NCT06278883
Conditions
Cardiovascular Diseases, Cancer, Liver Diseases, Hyperthermia
Interventions
Disease Risk Assessment
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
245 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
4
States / cities
Jacksonville, Florida • Orange Park, Florida
Conditions
Provider Burnout, Communication
Interventions
Communication coaching
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
859 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Malignant Neoplasms of Brain
Interventions
PEP-3 vaccine, sargramostim, Temozolomide
Biological · Drug
Lead sponsor
John Sampson
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
2
States / cities
Durham, North Carolina • Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

The HOP-STEP Intervention: Improving Maternal Health in Women With Lupus sIRB

NCT05818254
Conditions
Systemic Lupus Erythematosus, Contraception
Interventions
HOP-STEP (Healthy Outcomes in Pregnancy with SLE Through Education of Providers) Intervention, Routine Care
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Epilepsy, Sleep
Interventions
Lemborexant, Placebo
Drug
Lead sponsor
University of Manitoba
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Withdrawn Not applicable Interventional

Partial Heart Transplantation

NCT06055556
Conditions
Congenital Heart Disease
Interventions
Partial Heart Transplantation, Freshly procured valve
Procedure · Other
Lead sponsor
Duke University
Other
Eligibility
Up to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Osteoarthritis
Interventions
Lifestyle Behavioral Weight Management Program, Pain-Coping Skills Training, Standard Care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 85 Years
Enrollment
412 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Infection in Solid Organ Transplant Recipients, Complications of Organ Transplant, Respiratory Viral Infection
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Up to 18 Years
Enrollment
2,669 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Durham, North Carolina