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ClinicalTrials.gov public records Last synced Oct 3, 2026, 11:44 AM EDT

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Showing 25–48 of 372 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Penn State University Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Prunes Preventing Bone Loss in Perimenopause

NCT07120997
View directory record Official record
Conditions
Perimenopausal Bone Loss
Interventions
Prunes, Calcium supplement, Vitamin D Supplement
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
44 Years to 55 Years · Female only
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Early Phase 1 Interventional

Nitrate Supplementation and Cerebrovascular and Cognitive Function in Metabolic Syndrome

NCT05532423
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Beetroot Juice - Active, beetroot juice - Placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity

NCT01814072
View directory record Official record
Conditions
Weight Loss
Interventions
12 Telephone Coaching Sessions, 24 Telephone Coaching Sessions, Report to Primary Care Physician, Text Messages, Recommendations to use meal replacements, Buddy Training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional

Effect of Agave Syrup, Placebo, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Infants/Toddlers and Their Parents

NCT01721395
View directory record Official record
Conditions
Cough
Interventions
Agave Syrup
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
2 Months to 48 Months
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 23, 2015 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of an Adaptive Treatment Model for At-risk Family Caregivers

NCT00632684
View directory record Official record
Conditions
Stress
Interventions
Interviews with a single treatment planning session, Adaptive treatment model
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 23, 2011 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project MADD - NIH Underage DUI and Ride

NCT03506880
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen
Interventions
MADD Materials, Surgeon General Materials
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 3, 2026, 11:44 AM EDT
Terminated Not applicable Interventional

Retrobulbar Injection of Anesthesia Versus Healon 5 in the Management of Intraoperative Floppy Iris Syndrome

NCT00627913
View directory record Official record
Conditions
Intraoperative Floppy Iris Syndrome
Interventions
Healon 5 injection, Retrobulbar anesthetic injection
Procedure
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 100 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional

Portion Size Strategies for Management of Body Weight

NCT01474759
View directory record Official record
Conditions
Obesity
Interventions
Advice on diet, physical activity, and behavior change, Instruction in food portion size, Provision of pre-portioned foods, Advice on healthy eating for weight loss
Behavioral · Other
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 65 Years · Female only
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 15, 2015 · Synced Oct 3, 2026, 11:44 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

PaTH Clinical Data Research Network (CDRN) Study of Healthy Lifestyles and Health Care

NCT02456090
View directory record Official record
Conditions
Weight
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2030
U.S. locations
5
States / cities
Baltimore, Maryland • Danville, Pennsylvania • Hershey, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Peanut Consumption on Postprandial Inflammation, Glucose and Triglycerides

NCT01173042
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Peanuts, Glucose and whipping cream, Oil Blend
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 50 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Phase 1 Interventional

Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep

NCT00127686
View directory record Official record
Conditions
Cough, Respiratory Tract Infections
Interventions
Dextromethorphan, Buckwheat Honey
Drug
Lead sponsor
Penn State University
Other
Eligibility
2 Years to 18 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Mechanisms of Probiotics and Antibiotic-Associated Diarrhea

NCT04414722
View directory record Official record
Conditions
Antibiotic-associated Diarrhea
Interventions
Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet, BB-12, Control Yogurt
Drug · Biological · Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 65 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional Results available

Glutathione and Health With Post-Polio Syndrome

NCT01402570
View directory record Official record
Conditions
Post-polio Syndrome, Physical Activity, Depression, Pain, Sleep Disorders
Interventions
Glutathione
Dietary Supplement
Lead sponsor
University of Michigan
Other
Eligibility
50 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 17, 2017 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional Results available

Variations in Palatability and Portion Size of Vegetables on Meal Intake of Preschool Children

NCT03926065
View directory record Official record
Conditions
Feeding Behavior
Interventions
Plain Vegetables Served in 100% Portion Size, Plain Vegetables Served in 200% Portion Size, Enhanced Vegetables Served in 100% Portion Size, Enhanced Vegetables Served in 200% Portion Size
Other
Lead sponsor
Penn State University
Other
Eligibility
3 Years to 5 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 25, 2020 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional

Effects of Polyphenolic-rich Dark Chocolate/Cocoa and Almonds on Cardiovascular Disease Risk Factors

NCT01882881
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Healthy American Control Diet, Dark Chocolate/Cocoa Diet, Almond Diet, Dark Chocolate/Cocoa + Almond Diet
Other
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Canola Oil Multi-center Intervention Trial II

NCT03054779
View directory record Official record
Conditions
Cardiovascular Disease, Metabolic Syndrome
Interventions
Canola Oil, High oleic acid canola oil, Western diet oil combination
Other
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Influence of a Delivery System on the Efficacy of a Probiotic Intervention

NCT01399996
View directory record Official record
Conditions
Delayed Transit Time, Irregular Bowel Function
Interventions
Yogurt smoothie without probiotic, Yogurt smoothie with probiotic added post fermentation, Yogurt smoothie with probiotic added pre-fermentation, A capsule containing the probiotic
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional

Intensive Weekend Retreat Multi-Couple Group Therapy for PTSD

NCT03158558
View directory record Official record
Conditions
PTSD
Interventions
Accelerated, Multi-Couple Group CBCT for PTSD
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Killeen, Texas
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional

Nurse AMIE for Echo Show: Randomized Control Trial

NCT04673019
View directory record Official record
Conditions
Metastatic Breast Cancer
Interventions
Nurse AMIE (Addressing Metastatic Individuals Every day)
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Network Intervention to Prevent Vaping

NCT04678245
View directory record Official record
Conditions
Vaping, Preventive Psychiatry, Social Networking
Interventions
Above the Influence-Vaping (ATI-V)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
12 Years to 18 Years
Enrollment
3,950 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MR Elastography for the Herniated Intervertebral Disc

NCT03340545
View directory record Official record
Conditions
Intervertebral Disc Herniation
Interventions
Custom Magnetic Resonance Elastography Device
Other
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Valdecoxib Pretreatment on Pain and Secondary Hyperalgesia in Healthy Volunteers

NCT00260325
View directory record Official record
Conditions
Pain, Hyperalgesia
Interventions
valdecoxib
Drug
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 3, 2026, 11:44 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Elucidating the Necessary Active Components of Training

NCT05366023
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Change, Cognitive Impairment
Interventions
BUD1, BUD2, TDD1, TDD2, CSA10, CSA20, CSA30, CSA40
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
55 Years to 85 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seneca, South Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 3, 2026, 11:44 AM EDT
Completed Not applicable Interventional

Effects of Freeze Dried Strawberry Powder Supplementation on Vascular Function and Blood Markers of Cardiovascular Risk

NCT02557334
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Low Dose Strawberry Powder, High Dose Strawberry Powder, Placebo Powder
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
35 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2023 · Synced Oct 3, 2026, 11:44 AM EDT