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ClinicalTrials.gov public records Last synced Oct 7, 2026, 9:57 PM EDT

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Showing 25–48 of 274 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Tufts Medical Center Clear all
Completed Not applicable Interventional Results available

Palliative Care Educator

NCT04857060
View directory record Official record
Conditions
Advance Care Planning, Palliative Care, Alzheimer's Disease and Related Dementias, Doctor-patient Communication, Video Decision Aids
Interventions
ACP Educator led, video assisted discussion
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
11,174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Boston, Massachusetts • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 7, 2026, 9:57 PM EDT
Active, not recruiting Not applicable Interventional

NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer

NCT04986670
View directory record Official record
Conditions
Lung Cancer, Small Cell, Lung Cancer Metastatic, Lung Cancer Recurrent, Treatment Side Effects, Lung Cancer, Non-small Cell, Nutritional Imbalance
Interventions
Nutritional Counseling, Medically Tailored Meals (MTMs), Nutrition Prescription, Nutrition Assessment, Nutrition Toolkit, Monthly Emails
Behavioral · Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 100 Years
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
4
States / cities
Boston, Massachusetts • Columbus, Ohio • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Not applicable Interventional

Metabolomics for Identifying Biomarkers of Dietary Intake and Kidney Disease Progression

NCT03202914
View directory record Official record
Conditions
Dietary Modification, Kidney Diseases, Chronic
Interventions
Usual protein and phosphorus diet, Low protein and phosphorus diet, Very low protein and phosphorus
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 70 Years
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1988 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 29, 2017 · Synced Oct 7, 2026, 9:57 PM EDT
Completed No phase listed Observational

Structure and Function of Salivary Proteins

NCT00916682
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years and older
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 7, 2026, 9:57 PM EDT
Recruiting No phase listed Observational

Pulmonary Embolism and Right-to-Left Shunts

NCT07519876
View directory record Official record
Conditions
Pulmonary Embolism (PE), Right-to-Left Shunt, Stroke, Atrial Septal Defects, Patent Foramen Ovale (PFO), Pulmonary Arteriovenous Malformation
Interventions
Not listed
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Phase 4 Interventional

Photodynamic Therapy to Treat Actinic Damage in Patients With Squamous Cell Carcinoma (SCC) of the Lip

NCT00868088
View directory record Official record
Conditions
Actinic Cheilitis, Squamous Cell Carcinoma In-situ (SCC-is), Squamous Cell Carcinoma (SCC), Photodynamic Therapy (PDT), Mohs Surgery
Interventions
PDT prior to Mohs surgery
Procedure
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2011 · Synced Oct 7, 2026, 9:57 PM EDT
Suspended No phase listed Observational

Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)

NCT04838223
View directory record Official record
Conditions
Dry Eye, Neuropathic Pain
Interventions
Hyperosmolar Response, Proparacaine Challenge Test, Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Optional; only for Contact Lens Wearers, Ocular Pain Assessment Survey (OPAS), Visual Analogue Questionnaire
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
16
States / cities
Azusa, California • Pomona, California • San Francisco, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 7, 2026, 9:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ECA-enhanced Document Explanation RCT

NCT06435819
View directory record Official record
Conditions
Healthy
Interventions
Embodied Conversational Agent (ECA)
Other
Lead sponsor
Northeastern University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Phase 4 Interventional Results available

Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage

NCT03305575
View directory record Official record
Conditions
Cervical Incompetence
Interventions
Chloroprocaine, Bupivacaine
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Oct 7, 2026, 9:57 PM EDT
Terminated Phase 2 Interventional Results available

Zevalin for Patients With Incomplete Response to Chemo Prior to Autologous Stem Cell Transplant for Multiple Myeloma

NCT01207765
View directory record Official record
Conditions
Multiple Myeloma
Interventions
indium-111-ibritumomab tiuxetan, 90Y Zevalin
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Phase 3 Interventional Results available

Multicenter Study to Rule Out Myocardial Infarction by Cardiac Computed Tomography

NCT01084239
View directory record Official record
Conditions
Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina Pectoris
Interventions
Cardiac Computed Tomography
Radiation
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2014 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Parent Training to Promote Early Identification and Treatment of Childhood Behavioral Disorders

NCT00402857
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity, Attention Deficit and Disruptive Behavior Disorders
Interventions
Incredible Years Program
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
22 Months to 38 Months
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
9
States / cities
Chelsea, Massachusetts • Dorchester, Massachusetts • Jamaica Plain, Massachusetts + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2013 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Not applicable Interventional Results available

Pilot Study of High-flow Humidified Nasal Oxygen During Breaks From Noninvasive Ventilation

NCT01925534
View directory record Official record
Conditions
Acute Respiratory Failure, Treatment With Noninvasive Positive Pressure Ventilation
Interventions
High-flow humidified nasal oxygen delivery system, Standard oxygen therapy
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Winchester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Not applicable Interventional

A Study of a Technology-enabled Disease Management Program to Reduce Hospitalizations for Heart Failure

NCT02084992
View directory record Official record
Conditions
Congestive Heart Failure, Diastolic Heart Failure, Systolic Heart Failure
Interventions
Expanded technology disease management, Telephonic disease management
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts • Framingham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 17, 2019 · Synced Oct 7, 2026, 9:57 PM EDT
Completed No phase listed Observational

Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35

NCT01825278
View directory record Official record
Conditions
Obesity, Obstructive Sleep Apnea
Interventions
ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Not applicable Interventional Results available

Screening and Brief Advice to Reduce Teen Substance Use

NCT00227877
View directory record Official record
Conditions
Substance Related Disorders
Interventions
cSBA - New England, USA, cSBA - Prague, CZR
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
2,695 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
5
States / cities
Boston, Massachusetts • Cambridge, Massachusetts • Worcester, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Treatment for Bipolar Depression: Acute & Prophylactic Efficacy With Citalopram

NCT00562861
View directory record Official record
Conditions
Bipolar Disorder, Bipolar Depression
Interventions
citalopram + mood stabilizer, placebo + mood stabilizer
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2017 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Not applicable Interventional

Community Walks: Clinical Trial

NCT05147298
View directory record Official record
Conditions
Physical Inactivity
Interventions
eHealth phone program, Environment program
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 7, 2026, 9:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nutrition for Precision Health, Powered by the All of Us

NCT05701657
View directory record Official record
Conditions
Nutrition, Health, Dietary Habits
Interventions
Diet A, Diet B, Diet C
Other
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
8,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
14
States / cities
Birmingham, Alabama • Davis, California • Los Angeles, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 7, 2026, 9:57 PM EDT
Withdrawn Not applicable Interventional

Intranasal Neurostimulation for the Treatment of Neurosensory Abnormalities in CL Wearers (INTAC)

NCT04240587
View directory record Official record
Conditions
Contact Allergy, Neuropathic Pain
Interventions
TrueTear™ intranasal neurostimulator (ITN)
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Addition of Whole Grains to the Diets of Adults: A Study of Digestive Health and Natural Defenses

NCT01902394
View directory record Official record
Conditions
Digestive Health and Immune Function
Interventions
Whole grains, Refined grains
Other
Lead sponsor
Tufts University
Other
Eligibility
40 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2015 · Synced Oct 7, 2026, 9:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Supporting Mothers of Preterm Infants

NCT03013660
View directory record Official record
Conditions
PreTerm Birth
Interventions
Limited Financial Support
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Lowell, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 7, 2026, 9:57 PM EDT
Withdrawn Phase 2 Interventional

Topical Crisaborole in Patients with Alopecia Areata

NCT04299503
View directory record Official record
Conditions
Alopecia Areata
Interventions
Crisaborole Topical Ointment, Placebo Topical Ointment
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
2 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Oct 7, 2026, 9:57 PM EDT
Withdrawn Not applicable Interventional

The Impact of Interprofessional Training to Improve the Uptake of Noninvasive Ventilation in Patients Hospitalized With Severe COPD Exacerbation

NCT04206735
View directory record Official record
Conditions
Copd
Interventions
Interprofessional Education (IPE), Usual care
Other
Lead sponsor
Baystate Medical Center
Other
Eligibility
23 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Oct 7, 2026, 9:57 PM EDT