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ClinicalTrials.gov public records Last synced Oct 10, 2026, 10:46 PM EDT

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Showing 25–48 of 73 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: United States Army Research Institute of Environmental Medicine Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Pioglitazone on Exogenous Carbohydrate Oxidation During Steady-State Exercise at High Altitude

NCT06164665
View directory record Official record
Conditions
High Altitude
Interventions
Pioglitazone 15mg, Placebo
Drug · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combined Effects of Energy Density and Eating Rate on Appetite

NCT01406886
View directory record Official record
Conditions
Appetite
Interventions
Eating rate
Behavioral
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Energy and Physical Density Manipulation on Appetite

NCT05408390
View directory record Official record
Conditions
Appetite, Eating Behavior
Interventions
LPD+LED, HPD+LED, LPD+HED, HPD+HED
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Influence of Race and MitoQ Supplementation on Skin Blood Flow in the Cold

NCT06784531
View directory record Official record
Conditions
Cold Exposure
Interventions
Mitoquinone mesylate (MitoQ), Placebo, Cold Water Hand Immersion, Cold Air Exposure
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 40 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition Intervention to Promote Immune Recovery From Sleep Restriction

NCT03525184
View directory record Official record
Conditions
Sleep Restriction
Interventions
Additional protein and multi-nutrient beverage, Placebo beverage
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Environmental Intervention to Encourage Healthy Food Choices

NCT01921153
View directory record Official record
Conditions
Dietary Habits, Health Knowledge, Attitudes, Practice
Interventions
Healthy meal plates and trays
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2016 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Exercise With Overdressing

NCT07080853
View directory record Official record
Conditions
Heat Stress, Exertional, Heat Acclimation and Thermotolerance
Interventions
Exercise with Overdressing, Control Exercise
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 45 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 10, 2026, 10:46 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cocoa-rich Bioflavanol Supplementation Effects During Cold Exposure

NCT04359082
View directory record Official record
Conditions
Cold Exposure, Manual Dexterity, Gut Microbiome
Interventions
CocoaVia supplement, Placebo Pill
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 49 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 30, 2021 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Tyrosine on Behavioral, Physiological and Nutritional Status During Survive, Evade, Resist, Escape (SERE) School

NCT01823276
View directory record Official record
Conditions
Response to Severe Stress
Interventions
Tyrosine-Containing Bar, Placebo Bar
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years · Male only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2014 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults

NCT05464758
View directory record Official record
Conditions
Cold Exposure
Interventions
Repeated cold exposure
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 26, 2025 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of a Once Daily Calcium and Vitamin D Fortified Food Product to Improve Bone Microarchitecture

NCT02375503
View directory record Official record
Conditions
Bone Alteration, Dietary Modification
Interventions
Calcium/Vitamin D, Placebo
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 42 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 10, 2026, 10:46 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Pharmacological Countermeasures for High Altitude

NCT05300477
View directory record Official record
Conditions
Hypobaric Hypoxia
Interventions
Acetazolamide, Erythropoietin
Drug
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Human Hydration Status Monitoring

NCT01124903
View directory record Official record
Conditions
Dehydration
Interventions
Dehydration
Procedure
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 22, 2020 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Influences of Female Sex and Reproductive Hormones on Physiological Aspects of Heat Acclimation

NCT05292170
View directory record Official record
Conditions
Heat Stress, Exertional
Interventions
Heat acclimation
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 40 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse

NCT06228742
View directory record Official record
Conditions
Atrophy, Disuse, Muscle Atrophy, Muscular Disorders, Atrophic, Disuse Atrophy, Disuse Atrophy Muscle of Thigh
Interventions
Unilateral leg immobilization, Contralateral active leg
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Pacing (Guided Vs Unguided) Strategies Study

NCT02310334
View directory record Official record
Conditions
Body Temperature Changes
Interventions
Guided Exercise Session, Unguided Exercise Session
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
18 Years to 29 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Varying Energy Deficits on Protein Turnover at Rest and Carbohydrate Oxidation During Steady-state Exercise

NCT04910724
View directory record Official record
Conditions
Energy Supply; Deficiency, Severe, Energy Supply; Deficiency, Stress, Physiological
Interventions
Energy Deficit
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 10, 2026, 10:46 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Influence of Body Weight and Composition on Immune Recovery

NCT04737681
View directory record Official record
Conditions
BMI/Body Composition
Interventions
body composition
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Postprandial Glycemic Response to Polyphenol-fortified Snack Bars

NCT02763020
View directory record Official record
Conditions
Blood Sugar Response
Interventions
Fruit extracts high in polyphenols, placebo
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Protein Quality on Post-exercise Skeletal Muscle and Whole-body Protein Kinetics During Energy Deficit

NCT04004715
View directory record Official record
Conditions
Whole-body Protein Balance, Muscle Protein Synthesis
Interventions
Essential Amino Acid Enriched Whey Protein, Whey Protein, Military Ration Entree
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Recovery Protein Nutrition as a Countermeasure for Anabolic Resistance Following Sleep Loss

NCT06073080
View directory record Official record
Conditions
Sleep, Inadequate
Interventions
Protein Nutrition During Recovery
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 10, 2026, 10:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Tyrosine Supplementation on Cognitive Performance and Mood During Military Stress

NCT01913925
View directory record Official record
Conditions
Reaction to Severe Stress, Unspecified
Interventions
Tyrosine-Containing Food Bar, Placebo Bar
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Brunswick, Maine
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 10, 2026, 10:46 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Influences of Long-acting Reversible Contraceptives on Iron Status and Physiological Responses to Extreme Environments in Women

NCT06909695
View directory record Official record
Conditions
Contraception, Iron Deficiencies
Interventions
Blood volume and environmental testing
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 40 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 10, 2026, 10:46 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Influence of Wet Clothing on Thermal Protection

NCT05409937
View directory record Official record
Conditions
Low Body Temperatures
Interventions
Water-saturated Improved Hot Weather Combat Uniform, Water-saturated Army Combat Uniform, Water-saturated Army Combat Uniform + Silk Weights
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 49 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2023 · Synced Oct 10, 2026, 10:46 PM EDT