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ClinicalTrials.gov public records Last synced Oct 5, 2026, 9:22 PM EDT

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Showing 25–48 of 68 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: University Health Network, Toronto Clear all
Recruiting No phase listed Observational

EXtubation Related Complications - the EXTUBE Study (EXTUBE)

NCT06442930
View directory record Official record
Conditions
Extubation
Interventions
Not listed
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Tucson, Arizona • Little Rock, Arkansas • Gainesville, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Not applicable Interventional Results available

A Multicenter Prospective Study of Quality of Life in Adult Scoliosis

NCT00854828
View directory record Official record
Conditions
Scoliosis
Interventions
Surgical intervention, Non-operative intervention
Procedure · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 80 Years
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
7
States / cities
Chicago, Illinois • Louisville, Kentucky • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2021 · Synced Oct 5, 2026, 9:22 PM EDT
Withdrawn No phase listed Observational

Re-Evaluation of Systemic Early Neuromuscular Blockade and Transthoracic Ultrasound Assessment of the Diaphragm

NCT03132896
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Diaphragm Injury, Neuromuscular Blockade
Interventions
Not listed
Lead sponsor
University Health Network, Toronto
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
6
States / cities
Boston, Massachusetts • Springfield, Massachusetts • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Oct 5, 2026, 9:22 PM EDT
Recruiting Not applicable Interventional

FIGO 2018 Stage IB2 Cervical Cancer Treated With Neoadjuvant Chemotherapy Followed by Fertility Sparing Surgery

NCT04016389
View directory record Official record
Conditions
Cervical Cancer
Interventions
Cisplatin, Carboplatin, Paclitaxel, Trachelectomy
Drug · Procedure
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 5, 2026, 9:22 PM EDT
Active, not recruiting Not applicable Interventional

10°C vs 4°C Lung Preservation RCT

NCT05898776
View directory record Official record
Conditions
Lung Transplant, Organ Preservation
Interventions
Lung transplantation after 10°C donor lung preservation, Lung transplantation after standard ice cooler donor lung preservation
Device
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years to 80 Years
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Phoenix, Arizona • San Francisco, California • Coral Gables, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Effects of Exemestane on Bone Strength

NCT01144468
View directory record Official record
Conditions
Osteoporosis, Breast Cancer
Interventions
Not listed
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older · Female only
Enrollment
351 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2022
U.S. locations
2
States / cities
Sacramento, California • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Phase 2 Interventional Results available

12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II Depression

NCT02363738
View directory record Official record
Conditions
Bipolar Depression
Interventions
Infliximab, Saline
Drug · Other
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Phase 2Phase 3 Interventional

Antithrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC)

NCT04372589
View directory record Official record
Conditions
COVID-19, Pneumonia
Interventions
Heparin
Drug
Lead sponsor
University of Manitoba
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
13
States / cities
Atlanta, Georgia • Chicago, Illinois • Jefferson, Louisiana + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Oct 5, 2026, 9:22 PM EDT
Recruiting Phase 4 Interventional

Hypertonic Saline for MAC

NCT04921943
View directory record Official record
Conditions
Nontuberculous Mycobacterial Lung Disease, Nontuberculous Mycobacterium Infection
Interventions
Hypertonic saline, Azithromycin, Ethambutol, Rifampin
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
New York, New York • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 15, 2025 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Not applicable Interventional Results available

Internet Based Cognitive Behavioral Therapy in Pediatric Chronic Pancreatitis

NCT03707431
View directory record Official record
Conditions
Chronic Pancreatitis, Acute Recurrent Pancreatitis
Interventions
Web-based CBT, Pain Education
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
10 Years to 19 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Enrolling by invitation Not applicable Interventional

Neuronal Mechanisms of Human Episodic Memory

NCT04500119
View directory record Official record
Conditions
Epilepsy Intractable
Interventions
Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
13 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Phase 2Phase 3 Interventional

Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease

NCT03672630
View directory record Official record
Conditions
Mycobacterium Avium Complex, Nontuberculous Mycobacterium Infection
Interventions
Azithromycin, Ethambutol, Rifampin
Drug
Lead sponsor
Kevin Winthrop
Other
Eligibility
18 Years and older
Enrollment
474 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
25
States / cities
Loma Linda, California • San Diego, California • San Francisco, California + 21 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Phase 2 Interventional Results available

A Pilot Study to Assess the Efficacy of Rituximab Therapy in Treatment Resistant FSGS

NCT01573533
View directory record Official record
Conditions
Primary Focal Segmental Glomerulosclerosis
Interventions
Rituximab
Biological
Lead sponsor
Mayo Clinic
Other
Eligibility
6 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Chicago, Illinois • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Oct 5, 2026, 9:22 PM EDT
Not listed No phase listed Observational

Cardiac Output Measurement by TEE

NCT03349970
View directory record Official record
Conditions
Cardiac Disease
Interventions
Not listed
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Not applicable Interventional

A Randomized Controlled Trial of an Online Support Group for Sexual Distress Due to Gynecologic Cancer

NCT01654458
View directory record Official record
Conditions
Sexual Dysfunctions, Psychological, Uterine Cervical Neoplasms, Ovarian Neoplasms, Uterine Neoplasms, Genital Neoplasms, Female
Interventions
GyneGals Support Group
Behavioral
Lead sponsor
Women's College Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2021 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia

NCT00570557
View directory record Official record
Conditions
Deglutition Disorders, Dysphagia, Stroke
Interventions
TOR-BSST© Refresher Training
Other
Lead sponsor
University Health Network, Toronto
Other
Eligibility
Not listed
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Binghamton, New York
Source: ClinicalTrials.gov public record
Updated Jan 11, 2012 · Synced Oct 5, 2026, 9:22 PM EDT
Recruiting No phase listed Observational

International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

NCT06174727
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
11
States / cities
Coral Gables, Florida • Jacksonville, Florida • Sarasota, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Completed Phase 3 Interventional Results available

The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial

NCT01690988
View directory record Official record
Conditions
Delirium
Interventions
Ketamine (0.5 mg/kg), Normal Saline (placebo), Ketamine (1 mg/kg)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
746 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 5, 2026, 9:22 PM EDT
Completed No phase listed Observational Results available

Start Time Optimization of Biologics in Polyarticular JIA

NCT02593006
View directory record Official record
Conditions
Polyarticular Juvenile Rheumatoid Arthritis, Arthritis, Juvenile Idiopathic
Interventions
Not listed
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
2 Years to 18 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
52
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 41 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2021 · Synced Oct 5, 2026, 9:22 PM EDT
Completed No phase listed Observational

Prostate Cancer Localization With a Multiparametric Magnetic Resonance (MR) Approach

NCT01138527
View directory record Official record
Conditions
Prostate Cancer
Interventions
MRI examination
Other
Lead sponsor
Radboud University Medical Center
Other
Eligibility
Male only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
2
States / cities
Los Angeles, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 5, 2026, 9:22 PM EDT
Recruiting Phase 4 Interventional

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

NCT06802224
View directory record Official record
Conditions
Anesthesia, Surgery With General Anesthesia, Noncardiac Surgery, Hypotension During Surgery, Acute Kidney Injury (AKI), Myocardial Injury After Noncardiac Surgery (MINS), Vasopressor
Interventions
Norepinephrine, Phenylephrine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
18,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
9
States / cities
San Francisco, California • College Park, Maryland • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Recruiting No phase listed Observational

Nimodipine Variability in SAH

NCT07065903
View directory record Official record
Conditions
Subarachnoid Aneurysm Hemorrhage, Subarachnoid Hemorrhage, Aneurysmal
Interventions
Not listed
Lead sponsor
University of Alberta
Other
Eligibility
18 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Recruiting Not applicable Interventional

Platform of Randomized Adaptive Clinical Trials in Critical Illness

NCT05440851
View directory record Official record
Conditions
Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
Interventions
Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
Other · Drug
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
6,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
26
States / cities
Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 5, 2026, 9:22 PM EDT
Recruiting Phase 3 Interventional

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

NCT06217302
View directory record Official record
Conditions
Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1, Heart Failure
Interventions
Sotagliflozin, Placebo
Drug
Lead sponsor
Alessandro Doria
Other
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
13
States / cities
Stanford, California • Aurora, Colorado • Orlando, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 5, 2026, 9:22 PM EDT