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ClinicalTrials.gov public records Last synced Oct 15, 2026, 2:30 PM EDT

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Showing 481–504 of 1,662 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Brigham and Women's Hospital Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain

NCT05803096
View directory record Official record
Conditions
Prostate Disease, Malignancy, Benign Prostatic Hyperplasia, Prostate Cancer, Prostate Adenocarcinoma, Anxiety and Fear, Pain
Interventions
Self-Administered Nitrous Oxide, Oxygen
Drug · Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 85 Years · Male only
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Hypoglycemia and Autonomic Nervous System Function-B

NCT03429946
View directory record Official record
Conditions
Hypoglycemia, Healthy
Interventions
Spironolactone, Placebo, Hypoglycemic Hyperinsulinemic Clamp, Euglycemic Hyperinsulinemic Clamp
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2025
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers

NCT04113954
View directory record Official record
Conditions
Compartment Syndrome of Leg, Healthy
Interventions
Mepivacaine Injection
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 14, 2021 · Synced Oct 15, 2026, 2:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Ambulatory Cancer Care Electronic Symptom Self-Reporting for Surgical Patients

NCT03178045
View directory record Official record
Conditions
Patient Reported Outcomes
Interventions
Team Monitoring, Enhanced Feedback
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
19 Years and older
Enrollment
2,793 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2023 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Mineralocorticoid Receptor (MR) Antagonist (Eplerenone) vs Amlodipine and STRIATIN

NCT03683069
View directory record Official record
Conditions
Hypertension, Genetics Hypertension
Interventions
Eplerenone vs Amlodipine
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Use of Electronic Health Records for Addressing Overweight and Obesity in Primary Care

NCT01480466
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Obesity tools in the electronic health record
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years and older
Enrollment
65,278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 29, 2014 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifestyle Intervention in Preparation for Pregnancy (LIPP)

NCT03146156
View directory record Official record
Conditions
Obesity, Lifestyle-related Condition, Macrosomia, Fetal
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
4
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Eplerenone on Postprandial Inflammatory Response in Healthy Adults

NCT01786551
View directory record Official record
Conditions
Systemic Proinflammatory State
Interventions
Eplerenone
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Dalfampridine (4-AP) on Genioglossus Muscle Activity in Healthy Adults

NCT02656160
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Placebo, Dalfampridine
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Not applicable Interventional

The Contribution of Endothelin to Vasomotor Function in Diseased Coronary Arteries

NCT00115583
View directory record Official record
Conditions
Atherosclerosis, Coronary
Interventions
Drug Infusion (BQ-123)
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 9, 2016 · Synced Oct 15, 2026, 2:30 PM EDT
Completed No phase listed Observational

Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury

NCT02200120
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2015 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Sorbent Therapy of the Cutaneous Porphyrias

NCT01422915
View directory record Official record
Conditions
Erythropoietic Protoporphyria
Interventions
Colestipol
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
22 Years to 60 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 15, 2026, 2:30 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers Results available

Predictors of Postoperative Pain Following Oocyte Retrieval for Assisted Reproduction

NCT03105518
View directory record Official record
Conditions
Oocyte Retrieval, Postoperative Pain
Interventions
Fentanyl, Acetaminophen, Oxycodone
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Not applicable Interventional Results available

Gut Microbiome and p-Inulin in Hemodialysis

NCT02572882
View directory record Official record
Conditions
End-Stage Renal Disease, Gut Microbiome Dysbiosis
Interventions
p-inulin
Dietary Supplement
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Pharmacological Intervention for Symptomatic Mild Sleep Disordered Breathing

NCT04611750
View directory record Official record
Conditions
Sleep Disordered Breathing
Interventions
AD036, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 70 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App

NCT04330391
View directory record Official record
Conditions
Arthroplasties, Replacement, Weight Loss, Nutrition
Interventions
Remote dietitian supervised weight loss intervention and mobile app
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 2 Interventional

Protein Tyrosine Kinases (PTK) in Multiple Myeloma

NCT00165347
View directory record Official record
Conditions
Multiple Myeloma
Interventions
PTK787/ZK222584
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 21, 2007 · Synced Oct 15, 2026, 2:30 PM EDT
Completed No phase listed Observational

Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.

NCT07619508
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Tirzepatide, Semaglutide
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
100,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Digital Fall Prevention Study

NCT05432674
View directory record Official record
Conditions
Fall
Interventions
Digital Fall Prevention
Combination Product
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 15, 2026, 2:30 PM EDT
Withdrawn Not applicable Interventional

Fatty Acids in Airway Smooth Muscle of Asthmatics

NCT02809235
View directory record Official record
Conditions
Asthma
Interventions
coconut oil
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Oct 15, 2026, 2:30 PM EDT
Completed No phase listed Observational

Prospective Study of Insulin Resistance and Cardiovascular Disease Risk During Androgen Deprivation Therapy for Prostate Cancer

NCT00455624
View directory record Official record
Conditions
Prostate Cancer
Interventions
Androgen deprivation therapy
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2013 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

REVEAL III: Risk Evaluation and Education for Alzheimer's Disease

NCT00462917
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Pleiotropic info, in-person disclosure, AD-only info, in-person disclosure, Pleiotropic info, phone disclosure, AD-only info, phone disclosure
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
290 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts • Ann Arbor, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2018 · Synced Oct 15, 2026, 2:30 PM EDT
Completed Phase 3 Interventional

REVEAL - Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosis

NCT06788535
View directory record Official record
Conditions
Cardiac Amyloidosis
Interventions
I-124 evuzamitide
Drug
Lead sponsor
Sharmila Dorbala
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
20
States / cities
Scottsdale, Arizona • Duarte, California • San Francisco, California + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 15, 2026, 2:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Women With Epilepsy: Pregnancy Outcomes and Deliveries

NCT01259310
View directory record Official record
Conditions
Epilepsy
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
3
States / cities
Boston, Massachusetts • Great Neck, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Oct 15, 2026, 2:30 PM EDT