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Showing 505–528 of 528 matching trials from the live ClinicalTrials.gov search.
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Encouraging Calcium Absorption and Bone Formation During Early Puberty

NCT00022867
Conditions
Osteoporosis, Osteopenia
Interventions
Nondigestible oligosaccharide (NDO)
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
9 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
1
States / cities
Houston, Texas
Conditions
Polyarteritis Nodosa
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2019
U.S. locations
7
States / cities
Boston, Massachusetts • Rochester, Minnesota • Cleveland, Ohio + 3 more
Conditions
Rheumatoid Arthritis, Osteoarthritis
Interventions
Arthritis Self-Management Program, SMART Program
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2001
U.S. locations
4
States / cities
Palo Alto, California • Wichita, Kansas • Pittsburgh, Pennsylvania + 1 more
Conditions
Ankylosing Spondylitis
Interventions
Not listed
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Osteoarthritis
Interventions
Minimally Invasive Total Knee Arthroplasty [TKA Min], Total Knee Arthroplasty (TKA) Traditional
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
Boulder, Colorado • Denver, Colorado
Conditions
Pelvic Fractures, Fragility Fractures of the Pelvis (FFP)
Interventions
Surgical stabilization of pelvic fracture, Closed treatment of pelvic fracture
Procedure · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Rotator Cuff Tear
Interventions
Observational Cohort
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
45 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
4
States / cities
Boston, Massachusetts • Sioux Falls, South Dakota • Nashville, Tennessee + 1 more
Conditions
Osteopenia
Interventions
veverimer daily, veverimer every other day, Placebo
Drug · Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Fibromyalgia
Interventions
Cognitive Behavioral Therapy, Disease Education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Lupus Erythematosus, Systemic
Interventions
High-dose immunoablative therapy
Drug
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
3
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania • Milwaukee, Wisconsin
Conditions
Immunologic Deficiency Syndrome
Interventions
Not listed
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
Not listed
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Rotator Cuff Tear
Interventions
Arthroscopic Rotator Cuff Surgery, Physical Therapy
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
40 Years to 84 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
19
States / cities
Phoenix, Arizona • San Francisco, California • Denver, Colorado + 14 more
Completed Phase 2 Interventional Accepts healthy volunteers

Bone Response to Soy Isoflavones in Women

NCT00043745
Conditions
Osteopenia, Osteoporosis
Interventions
Soy isoflavones, Extract tablets
Dietary Supplement
Lead sponsor
Iowa State University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
2
States / cities
Davis, California • Ames, Iowa
Recruiting No phase listed Observational Accepts healthy volunteers

Study of Systemic Lupus Erythematosus

NCT00001372
Conditions
Systemic Lupus Erythematosus
Interventions
Not listed
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
3 Years to 120 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1994
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Natural History and Development of Spondyloarthritis

NCT01422694
Conditions
Arthritis, Spondylitis, Ankylosing
Interventions
Not listed
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
2 Years to 99 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Early Phase 1 Interventional Results available

Calcitriol Monotherapy for X-Linked Hypophosphatemia

NCT03748966
Conditions
X-linked Hypophosphatemia, Hypophosphatemic Rickets, Hypophosphatemic Rickets, X-Linked Dominant
Interventions
Calcitriol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
3 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Chronic Pain and Relapse Prevention
Interventions
Chronic pain therapeutic interactive voice response (TIVR) system
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Juvenile Idiopathic Arthritis, Rheumatoid Arthritis, Obesity
Interventions
Etanercept Optimal dosing
Drug
Lead sponsor
Duke University
Other
Eligibility
2 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Pediatric Crohn's Disease
Interventions
Methotrexate, Sugar pill (placebo)
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Up to 20 Years
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
32
States / cities
Birmingham, Alabama • Alto, California • New Haven, Connecticut + 27 more
Completed No phase listed Observational Accepts healthy volunteers

Genetic and Family Studies of Inherited Muscle Diseases

NCT00001331
Conditions
Dermatomyositis, Glycogen Storage Disease Type II, Glycogen Storage Disease Type VII, Myositis, Polymyositis
Interventions
Not listed
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
1993 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Molecular Transducers of Physical Activity Consortium (MoTrPAC) - Pediatric Protocol

NCT04151199
Conditions
Physical Activity
Interventions
EE Training
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
10 Years to 17 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Irvine, California
Conditions
Mixed Connective Tissue Disease (MCTD), Systemic Lupus Erythematosus (SLE)
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 100 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2025
U.S. locations
1
States / cities
Miami, Florida
Completed Phase 2 Interventional Accepts healthy volunteers

Effects of Jumping on Growing Bones

NCT00000405
Conditions
Osteoporosis
Interventions
Exercise intervention
Procedure
Lead sponsor
Oregon State University
Other
Eligibility
5 Years to 10 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2008
U.S. locations
1
States / cities
Corvallis, Oregon
Conditions
Chronic Knee Pain, Osteoarthritis, Knee
Interventions
A worksite activity-diet intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Chicago, Illinois