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ClinicalTrials.gov public records Last synced Oct 30, 2026, 10:40 PM EDT

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Showing 553–576 of 3,667 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Mayo Clinic Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Use of the OPTIMAL Theory of Motor Learning With the Lower Quarter Y-Balance Test

NCT05113797
View directory record Official record
Conditions
Balance
Interventions
Lower Quarter Y-Balance Test, OPTIMAL motor learning theory
Diagnostic Test · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Oct 30, 2026, 10:40 PM EDT
Recruiting Not applicable Interventional

Continuous Glucose Monitor for Mayo Clinic Advanced Care at Home Patients

NCT05880810
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Continuous Glucose Monitor Dexcom G6 PRO
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Phase 1 Interventional

Study of Enzalutamide With and Without Sorafenib in Advanced Hepatocellular Carcinoma Patients

NCT02642913
View directory record Official record
Conditions
Hepatocellular Carcinoma
Interventions
Enzalutamide, Enzalutamide with Sorafenib
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
5
States / cities
San Francisco, California • St Louis, Missouri • Buffalo, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2021 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Hydroxyproline Influence on Oxalate Metabolism

NCT02038543
View directory record Official record
Conditions
Hyperoxaluria
Interventions
Hydroxyproline and Leucine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
15 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Networks, Informatics, Technology, and Education in Care for People With Diabetes

NCT00421850
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
UNITED Planned Care
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
3,491 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 23, 2011 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Allergy Skin Patch Artificial Intelligence (AI)

NCT05339750
View directory record Official record
Conditions
Allergic Contact Dermatitis
Interventions
AI-based smartphone application, Allergen patch
Device · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 6, 2023 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Phase 1 Interventional

Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

NCT03021460
View directory record Official record
Conditions
Metastatic Melanoma, Stage III Cutaneous Melanoma AJCC v7, Stage IIIA Cutaneous Melanoma AJCC v7, Stage IIIB Cutaneous Melanoma AJCC v7, Stage IIIC Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7, Unresectable Melanoma
Interventions
Ibrutinib, Laboratory Biomarker Analysis, Pembrolizumab
Drug · Other · Biological
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Recruiting Not applicable Interventional

Managing Depressive Symptoms in ADPKD

NCT07745920
View directory record Official record
Conditions
Autosomal Dominant Polycystic Kidney Disease
Interventions
Mayo Clinic-Approved Education, Digital Neuropathy, Capacity Coaching
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Active, not recruiting Not applicable Interventional

Electromagnetic Transduction Therapy on Osteoarthritis in the Foot and Ankle

NCT06696118
View directory record Official record
Conditions
Osteoarthritis Ankle, Osteoarthritis Foot
Interventions
Electromagnetic Transduction Therapy (EMTT)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Phase 1 Interventional

Bortezomib, Melphalan, and Total-Body Irradiation Before Stem Cell Transplant in Treating Patients With Multiple Myeloma

NCT01936090
View directory record Official record
Conditions
DS Stage I Plasma Cell Myeloma, DS Stage II Plasma Cell Myeloma, DS Stage III Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Interventions
Bortezomib, Total-Body Irradiation, Melphalan, Autologous Bone Marrow Transplantation, Autologous Hematopoietic Stem Cell Transplantation, Peripheral Blood Stem Cell Transplantation, Laboratory Biomarker Analysis
Drug · Radiation · Procedure + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 24, 2018 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Phase 2 Interventional Results available

Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study

NCT03033225
View directory record Official record
Conditions
Advanced Pancreatic Carcinoma, Locally Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma, Pancreatic Neoplasm, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Unresectable Pancreatic Carcinoma
Interventions
Endoscopic Ultrasound, Fluorescence Imaging, Photodynamic Therapy, Quality-of-Life Assessment, Questionnaire Administration, Verteporfin
Procedure · Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 30, 2026, 10:40 PM EDT
Active, not recruiting Not applicable Interventional

Neurophysiologically Based Brain State Tracking and Modulation in Focal Epilepsy

NCT03946618
View directory record Official record
Conditions
Epilepsy
Interventions
Medtronic Summit System, Olympus
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Not applicable Interventional Results available

Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy

NCT03341533
View directory record Official record
Conditions
Pain, Postoperative, Hysterectomy, Narcotic Use, Cryotherapy Effect
Interventions
Ice packs plus usual post-op analgesia, Usual post-op analgesia
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Phase 1 Interventional

Alisertib and Fulvestrant in Treating Patients With Hormone Receptor Positive Breast Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

NCT02219789
View directory record Official record
Conditions
Estrogen Receptor Positive, Progesterone Receptor Positive, Recurrent Breast Carcinoma, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer
Interventions
Alisertib, Fulvestrant, Laboratory Biomarker Analysis
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 30, 2026, 10:40 PM EDT
Recruiting Phase 4 Interventional

Itraconazole Therapy In Bronchiectasis With Airway Mold

NCT07283497
View directory record Official record
Conditions
Bronchiectasis, Fungal Infection of Upper Respiratory Tract
Interventions
Itraconazole 200 mg
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Early Phase 1 Interventional

Kinesio Taping Effectiveness on Idiopathic Toe Walking

NCT02025582
View directory record Official record
Conditions
Idiopathic Toe Walking
Interventions
Kinesio Tape of the Ankle
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Years to 10 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2016 · Synced Oct 30, 2026, 10:40 PM EDT
Terminated No phase listed Observational

Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary, Sarcoma or Melanoma Cancers and Changes in Gut Microbiome: Potential for Precision Therapeutics

NCT05819827
View directory record Official record
Conditions
Bladder Cancer, Prostate Cancer, Testicular Cancer, Bladder Carcinoma, Genitourinary System Carcinoma, Malignant Testicular Neoplasm, Melanoma, Prostate Carcinoma, Sarcoma
Interventions
Blood and Tissue
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 30, 2026, 10:40 PM EDT
Withdrawn Not applicable Interventional

Mindfulness to Mitigate the Effect of Anxiety-depression-fear in Chronic Obstructive Pulmonary Disease (COPD)

NCT03385317
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Mindfulness
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 28, 2017 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Phase 1 Interventional Results available

Lenalidomide and Dexamethasone With or Without Anakinra in Treating Patients With Early Stage Multiple Myeloma

NCT02492750
View directory record Official record
Conditions
Indolent Plasma Cell Myeloma, Plasma Cell Myeloma, Smoldering Plasma Cell Myeloma
Interventions
Anakinra, Dexamethasone, Laboratory Biomarker Analysis, Lenalidomide, Placebo
Biological · Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 30, 2026, 10:40 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

GENetic Education Risk Assessment and TEsting Study

NCT03762590
View directory record Official record
Conditions
Candidates for Hereditary Pancreatic Cancer Testing
Interventions
Doxy.me genetic education +/- Color Genomics genetic education, Color Genomics genetic education
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Recruiting No phase listed Observational

Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vulvar Lesions: A Pilot Study

NCT07886203
View directory record Official record
Conditions
Vulvar Intraepithelial Neoplasia, HPV-Independent, Vulvar Squamous Cell Carcinoma, Vulvar Squamous Intraepithelial Lesion, HPV-Associated
Interventions
Non-Interventional Study
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Evaluate Endoflip Normal Ranges Data in Healthy Volunteers

NCT04809883
View directory record Official record
Conditions
Healthy
Interventions
Endoflip measurement of gastric and pyloric function
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 30, 2026, 10:40 PM EDT
Terminated Phase 2 Interventional

Treating Breast Cancer Patients Undergoing Trastuzumab Treatment With Carvedilol to Reduce Incidence of Heart Failure

NCT03879629
View directory record Official record
Conditions
Breast Cancer
Interventions
Carvedilol
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
5
States / cities
Phoenix, Arizona • Jacksonville, Florida • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 30, 2026, 10:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sulindac Capsules Compared With Sulindac Tablets in Healthy Volunteers

NCT00343629
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
sulindac, pharmacological study
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 30, 2026, 10:40 PM EDT