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ClinicalTrials.gov public records Last synced Nov 6, 2026, 12:38 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 577–600 of 3,232 matching trials from the live ClinicalTrials.gov search.

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Conditions: Opioid Use Disorder, Overdose, Drug, Overdose, Substance Use (Drugs, Alcohol)
Interventions: Community Paramedic Standard of Care (CP SOC), CROSSROADS; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 4
States / cities: Miami, Florida • Boston, Massachusetts • Durham, North Carolina + 1 more

Conditions: Heart Failure, Diastolic, Diastolic Heart Failure, Heart Failure, Normal Ejection Fraction, Heart Failure, Preserved Ejection Fraction
Interventions: Bimagrumab, Placebo; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years and older
Enrollment: 540 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Van Nuys, California • North Miami Beach, Florida • Dallas, Texas

Conditions: Chronic Low Back Pain (CLBP)
Interventions: Empowering Pain Psychology Access and Collaboration (EPPAC), Usual Care Pain Psychology Evaluation; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cystic Fibrosis (CF)
Interventions: Common form supplementation, Uncommon nutrient supplementation; Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Concussion, Depression
Interventions: ONE-D TMS protocol and d-cycloserine (125 mg); Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Ocala, Florida

Conditions: Substance Abuse, HIV
Interventions: Tool to provide re-entry support and improve linkage to healthcare and social services; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Traumatic Brain Injury, Traumatic Brain Injury (TBI), Hemiplegia and Hemiparesis
Interventions: Transcutaneous Spinal Cord Stimulation, Sham; Procedure · Other
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Chicago, Illinois • West Orange, New Jersey

Conditions: NSCLC, Non-Small Cell Lung Cancer, Lung Cancer, Prostate Cancer, Thymic Epithelial Tumors, TETs, Thymic Carcinomas, Thymomas, Metastatic Castrate-resistant Prostate Cancer, mCRPC
Interventions: STAR0602, Nivolumab; Drug
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years to 120 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Chronic Musculoskeletal Pain, Chronic Shoulder Pain, Chronic Knee Pain
Interventions: Laterality Training, Sham (No Treatment); Behavioral · Other
Lead sponsor: Hawaii Pacific University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Moline, Illinois • Davenport, Iowa

Conditions: CAD - Coronary Artery Disease
Interventions: Heartflow Analysis; Device
Lead sponsor: HeartFlow, Inc.; Industry
Eligibility: 40 Years to 79 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: New York, New York

Conditions: Epilepsy
Interventions: Brain Interchange System; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 3 Years to 70 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Rochester, Minnesota • Houston, Texas

Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Interventions: Discontinuing Bruton tyrosine kinase inhibitors (BTKi) therapy; Other
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Opioid Use Disorders, Cannabis Use
Interventions: Inhaled Cannabis, Intranasal Opioid; Drug
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 55 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Pancreatic Cancer, PDAC - Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Carcinoma, Locally Advanced Pancreatic Cancer
Interventions: Avutometinib (VS-6766) + Defactinib (VS-6063); Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Old Adults, Sleep Quality, Kava, Mobility Impairment, Physical Activity and Stress, Physical Impairment, Sedentary Lifestyle in Patients Over 70
Interventions: AB-free kava, Placebo; Drug · Other
Lead sponsor: University of Florida; Other
Eligibility: 70 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Burns, Wound Infection
Interventions: Methylene Blue, Blue Light Illumination; Drug · Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Social Cognition, Personality Disorder, Mental Health, Interpersonal Conflict
Interventions: Social Learning Task Battery, Clinical Cohort, Social Learning Task Battery, Online Cohort; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 100 Years
Enrollment: 1,612 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Alcohol Withdrawal, Alcohol Abstinence, Alcohol Use Disorder
Interventions: Sodium Acetate, Placebo; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 21 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Post-ect Agitation, Post-ictal Agitation
Interventions: Weighted blanket, Usual Care Group; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: People Who Use Opioids/People With Opioid Use Disorder (OUD)
Interventions: Implementation strategy bundle; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 536 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 4
States / cities: Pittsburgh, Pennsylvania

Conditions: Lung Cancer, Non Small Cell Lung Cancer, Lung Cancer Recurrent
Interventions: Haystack™ ctDNA Assay; Diagnostic Test
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 90 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Autism Spectrum Disorder, Autism
Interventions: Early Diagnostic Response Model Expanded; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 16 Months to 36 Months
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: AI Companionship
Interventions: AI Companion Interaction; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Medication Adherence, Breast Cancer
Interventions: Educational video, Symptom monitoring card, Text reminders; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: Boston, Massachusetts

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The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study

A Study of Bimagrumab in Participants With HFpEF

Empowering Pain Psychology Access and Collaboration (EPPAC) to Improve Treatment Engagement Among Medicaid-insured Adults With Chronic Low Back Pain

Nutrition Supplement for Cystic Fibrosis

Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athletes With Co-morbid Depression and Concussion

Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved in the Carceral System

Spinal Stimulation and Gait Training to Improve Mobility in TBI

STAR0602 With Nivolumab in Non Small Cell Lung Cancer and in Metastatic Castrate-Resistant Prostate Cancer, and STAR0602 Alone in Thymic Carcinoma

Laterality Training and Pain Drawings

REFINE-CAC Protocol: Risk Evaluation With AI-CPA + HCS For Patients IN Whom Calcium is confirmEd to Improve Coronary Artery Disease Care

Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations

Study on Treatment Outcome Patterns for Patients With CLL After Discontinuation of BTK Inhibitors

Cannabis and Opioid Use Disorder, Study 2

Neoadjuvant Avutometinib/Defactinib and mFOLFIRINOX Combination Therapy in Pancreatic Adenocarcinoma

Kava Aging and Mobility Study

Topical Methylene Blue-Photodynamic Therapy (MB-PDT) for Burn Wound Infection

Neurocomputational Dynamics of Cooperation

Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized Patients

Peri-procedural Weighted Blanket Use for ECT

Prescribe to Prevent HIV: A Hybrid Trial Helping Addiction Clinics Prevent HIV & Infections Through Safer Drug Use Support

Trial of ctDNA of Guidance to Determine PostOperative Radiation Therapy

Early Diagnostic Telehealth Pilot for Moderate- and High-Risk Children: Evaluating Assessment Protocols and Efficiency in Georgia's Early Intervention Program

How Do Artificially Intelligent Companions Influence Psychological Outcomes?

Adjuvant Endocrine Therapy Adherence Intervention Pilot in Rwanda