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ClinicalTrials.gov public records Last synced Oct 15, 2026, 9:06 PM EDT

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Showing 673–696 of 779 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Children's Hospital of Philadelphia Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Treatment to Improve Sleep in Caregivers With Insomnia and a Child With Autism

NCT05373537
View directory record Official record
Conditions
Autism Spectrum Disorder, Insomnia Chronic, Caregiver Burden
Interventions
Cognitive behavioral therapy for Insomnia
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
3 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Not applicable Interventional

Safer Food Allergy Management for Adolescents

NCT03284372
View directory record Official record
Conditions
Food Allergy, Adherence, Medication
Interventions
Text Message Only, Text message + Incentive 1
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
15 Years to 19 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 25, 2021 · Synced Oct 15, 2026, 9:06 PM EDT
Recruiting No phase listed Observational

Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

NCT04093986
View directory record Official record
Conditions
Sickle Cell Disease, Sickle Cell Anemia
Interventions
Chart Review, Survey
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Validation of Oxygen Nanosensor in Mitochondrial Myopathy

NCT04086329
View directory record Official record
Conditions
Mitochondrial Myopathies, Mitochondrial Diseases
Interventions
Nanosensor
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Recruiting Phase 4 Interventional

AWARE: Management of ADHD in Autism Spectrum Disorder

NCT05916339
View directory record Official record
Conditions
ADHD, Autism Spectrum Disorder
Interventions
Randomization to either Amphetamine (AMP) class of stimulant medication or Methylphenidate (MPH) class of stimulant medication, Randomization to either Alpha 2 agonist class of medication or alternate class of stimulant.
Drug
Lead sponsor
Daniel Coury
Other
Eligibility
4 Years to 17 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
10
States / cities
Irvine, California • Los Angeles, California • Portland, Maine + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 15, 2026, 9:06 PM EDT
Terminated Phase 1 Interventional Results available

Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease

NCT03417999
View directory record Official record
Conditions
Dexmedetomidine, Congenital Heart Disease
Interventions
Dexmedetomidine
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Month to 6 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Not applicable Interventional

Improving Care, Accelerating Recovery and Education

NCT06233747
View directory record Official record
Conditions
Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
Interventions
Improving Care, Accelerating Recovery & Education (ICARE)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Crisis Interventions for Pediatric Providers - Autism Version

NCT07508436
View directory record Official record
Conditions
Autism, Suicide Prevention
Interventions
Safety Planning Intervention, Crisis Interventions for Pediatric Providers - Autism version (CIPP-A)
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

NCT01484678
View directory record Official record
Conditions
Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 62 Years · Male only
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
3
States / cities
Gainesville, Florida • Portland, Oregon • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

SmART-TBI: Supplementation With Amino Acid Rehabilitative Therapy in TBI

NCT04603443
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Branched Chain Amino Acids, Protein Control
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Acetazolamide Efficacy in Ataxia in PMM2-CDG

NCT04679389
View directory record Official record
Conditions
Pmm2-CDG, CDG1A
Interventions
Placebo, Acetazolamide
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
4 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Rochester, Minnesota • Philadelphia, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 15, 2026, 9:06 PM EDT
Active, not recruiting Early Phase 1 Interventional

Fludarabine Based RIC for Bone Marrow Failure Syndromes

NCT02928991
View directory record Official record
Conditions
Bone Marrow Failure Syndromes
Interventions
MRD-BMT with Fludarabine-based RIC for Acquired AA, MRD-BMT with Fludarabine-based RIC for iBMF with trilineage aplasia, MRD-BMT with Fludarabine-based RIC for iBMF without trilineage aplasia
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 22 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Enrolling by invitation Phase 1 Interventional

GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma

NCT05650749
View directory record Official record
Conditions
Refractory Neuroblastoma, Relapsed Neuroblastoma, High-risk Neuroblastoma, Retinoblastoma, Metastatic Retinoblastoma
Interventions
GPC2 CAR T cells
Biological
Lead sponsor
Stephan Grupp MD PhD
Other
Eligibility
1 Year and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Recruiting No phase listed Observational

Registry for Systemic Eczema Treatments

NCT06136767
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
1 Year to 26 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Nasal Expiratory Positive Airway Pressure for the Treatment of Pediatric Obstructive Sleep Apnea Syndrome

NCT01768065
View directory record Official record
Conditions
Organic Pediatric Obstructive Sleep Apnea
Interventions
Nasal Expiratory Positive Airway Pressure Device, placebo sham
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 16 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 15, 2026, 9:06 PM EDT
Not yet recruiting Not applicable Interventional

From Kitchen to Clinic

NCT07454902
View directory record Official record
Conditions
Pediatric Cancer, Malnutrition, Child, Caregiver Burden
Interventions
Medically Tailored Meals, Caregiver Coaching
Other · Behavioral
Lead sponsor
Drexel University
Other
Eligibility
5 Years to 21 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Tailored Adherence Incentives for Childhood Asthma Medications (TAICAM) Trial

NCT03907410
View directory record Official record
Conditions
Medication Adherence, Asthma in Children
Interventions
Nominal Financial Incentives, Daily Adherence Reminders/Adherence Performance Feedback
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 12 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Oct 15, 2026, 9:06 PM EDT
Not yet recruiting Not applicable Interventional

Technology Knowledge Optimization for Type 1 Diabetes in Schools

NCT07482488
View directory record Official record
Conditions
Type 1 Diabetes (T1D)
Interventions
TeKnO T1D curriculum
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
5 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Phase 2 Interventional Results available

CHP 834 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transportation for T and B Cell Depletion

NCT00579124
View directory record Official record
Conditions
Immunodeficiencies
Interventions
CliniMACs
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 22 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 15, 2026, 9:06 PM EDT
Active, not recruiting Not applicable Interventional

Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF

NCT03047746
View directory record Official record
Conditions
Acquired Aplastic Anemia, Paroxysmal Nocturnal Hemoglobinuria, Inherited Bone Marrow Failure Syndromes
Interventions
CliniMACs
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 25 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Not applicable Interventional

CPR Rescuer Fatigue on Chest Compression Effectiveness

NCT01117896
View directory record Official record
Conditions
Rescuer Fatigue During CPR
Interventions
Chest compression on adult and pedi manikins, Use of stepstool during chest compressions
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
22 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 26, 2012 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Not applicable Interventional

HSAT for OSA Management in Children

NCT05516524
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes, Sleep Disturbance
Interventions
Home sleep apnea test, PSG
Diagnostic Test
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 12 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Phase 3 Interventional Results available

Stepped Preventive Care to Reduce the Impact of Acute Pediatric Injury

NCT00451282
View directory record Official record
Conditions
Stress Disorders, Posttraumatic
Interventions
stepped preventive care
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 17 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2015 · Synced Oct 15, 2026, 9:06 PM EDT
Completed Not applicable Interventional

Depression Prevention Initiative - A Study of Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) in School Settings

NCT01201382
View directory record Official record
Conditions
Depression
Interventions
IPT-AST, Group Counseling
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 17 Years
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
2
States / cities
Piscataway, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 15, 2026, 9:06 PM EDT