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Showing 673–696 of 2,471 matching trials from the live ClinicalTrials.gov search.
Recruiting Phase 4 Interventional Accepts healthy volunteers

Computational Assessment of GABA Receptor Modulation in PTSD

NCT06852469
Conditions
Stress Disorders, Post-Traumatic
Interventions
Lorazepam 1 mg tablet, Placebo tablet
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Diego, California
Conditions
Suicide Prevention, Suicide Attempt, Suicide Ideation
Interventions
Virtual Hope Box Enhanced Facilitation, Enhanced Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
928 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Low Back Pain
Interventions
self-administered acupressure
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
297 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed No phase listed Observational Accepts healthy volunteers

Predictors of Decompressive Laminectomy Outcomes

NCT02215551
Conditions
Lumbar Spinal Stenosis
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 90 Years
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
7
States / cities
Denver, Colorado • Decatur, Georgia • Ann Arbor, Michigan + 4 more
Completed No phase listed Observational Accepts healthy volunteers Results available

Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke

NCT00721357
Conditions
Stroke
Interventions
Treadmill walking, Magnetic resonance spectroscopy
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Central Auditory Processing Disorders Associated With Blast Exposure

NCT00554801
Conditions
Central Auditory Processing Disorder, Traumatic Brain Injury, Hearing Loss
Interventions
Audiological testing
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Hypertension, Obesity
Interventions
gamification with collaboration, gamification with competition
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
725 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Results available

Social Cognition Intervention

NCT01267019
Conditions
Psychosis
Interventions
social cognitive training with in vivo augmentation, social cognitive training, non-social skills training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
West Los Angeles, California
Conditions
Multimorbidity
Interventions
Peer health coach intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Completed Phase 2 Interventional Results available

Metformin in Kidney Disease

NCT02252081
Conditions
Chronic Kidney Disease, Cardiovascular Disease, Metabolic Syndrome
Interventions
metformin, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Phase 1 Interventional Accepts healthy volunteers

rTMS for Emotional Difficulties in Verterans

NCT03749967
Conditions
Mental Health, Depression, rTMS, Anxiety, PTSD, Psychosocial Impairment
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Acute Coronary Syndrome
Interventions
Intervention, Usual care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 90 Years
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
4
States / cities
Little Rock, Arkansas • Denver, Colorado • Durham, North Carolina + 1 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Randomized Controlled Effectiveness Trial of VA S.A.V.E.

NCT06470867
Conditions
Suicide Prevention
Interventions
VA S.A.V.E., Control training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
701 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Stroke
Interventions
Robot-Assisted Therapy - MIT-MANUS System, Intensive Comparison Therapy, Usual Care
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
5
States / cities
West Haven, Connecticut • Gainesville, Florida • Baltimore, Maryland + 2 more
Conditions
Acute Coronary Artery Syndrome
Interventions
intensive LDL-lowering therapy, standard statin monotherapy
Device · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
31 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
4
States / cities
Denver, Colorado • Oklahoma City, Oklahoma • Nashville, Tennessee + 1 more
Conditions
Heart Failure, Congestive, Cardiomyopathy
Interventions
Telephone Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
438 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Phase 2 Interventional Results available

IOK Treatment Study

NCT01605799
Conditions
Posttraumatic Stress Disorder
Interventions
IOK Killing Treatment, Wait list control group
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Results available

Mindfulness-Based Recovery in Veterans

NCT02326363
Conditions
Substance Abuse, Depression, Anxiety Disorder
Interventions
Mindfulness Based Relapse Prevention (MBRP), Twelve-Step Facilitation Intervention (TSF)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Tuscaloosa, Alabama • Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Real-World Benefit From Directional Hearing Aids

NCT00438334
Conditions
Hearing Loss
Interventions
Programmable directional/omni-directional hearing aid
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
Not listed
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2004
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Diabetes Mellitus, Type 2, Hypoglycemia
Interventions
GTS (Continuous Glucose Monitoring), POC (Point of Care)
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Completed No phase listed Observational Results available

Enhancing Access to Insomnia (EASI) Care in VA PCMHI Clinics

NCT04350866
Conditions
Chronic Insomnia
Interventions
Expert Recommendations for Implementing Change bundle of strategies, Brief Behavioral Treatment for Insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
277,920 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Brain Concussion, Blast Injuries
Interventions
Goal Management Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Stigma, Co-Occurring Disorders, Substance Use Disorder, Mental Health Disorder, Veterans
Interventions
Veterans Affairs-Honest, Open, Proud
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Bedford, Massachusetts
Conditions
Diabetic Nephropathy
Interventions
spironolactone
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Dayton, Ohio