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ClinicalTrials.gov public records Last synced Oct 9, 2026, 2:29 AM EDT

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Showing 49–72 of 85 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Carilion Clinic Clear all
Not listed Phase 4 Interventional

Correlation of Serum Level of Perampanel (PER) Level to Cerebrospinal Fluid (CSF) Levels of PER

NCT04118829
View directory record Official record
Conditions
Epilepsy, Seizures
Interventions
Perampanel
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Comparison of Flow Regulated Nasal Oxygen Delivery System (FRNDS) Cannula and Plethysmography Belts

NCT06713213
View directory record Official record
Conditions
Respiratory Failure With Hypoxia
Interventions
Flow-regulated nasal oxygen delivery system (FRNDS)
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 9, 2026, 2:29 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives

NCT03291743
View directory record Official record
Conditions
Crohn Disease, Genetic Predisposition, IBD
Interventions
Capsule endoscopy
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Oct 9, 2026, 2:29 AM EDT
Terminated Not applicable Interventional Results available

Diagnostic Performance of an Antigen Test for SARS-CoV-2 Infection (COVID-19)

NCT04610489
View directory record Official record
Conditions
Covid-19
Interventions
Quidel Sofia SARS Antigen FIA
Diagnostic Test
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 9, 2026, 2:29 AM EDT
Not listed Phase 4 Interventional

Nebulized N-Acetyl Cysteine for Bronchiolitis in Inpatient Hospital Use

NCT03364218
View directory record Official record
Conditions
Bronchiolitis Acute
Interventions
N-Acetyl Cysteine
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
1 Week to 2 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 9, 2026, 2:29 AM EDT
Terminated Not applicable Interventional

Radial Versus Femoral Secondary Access During TAVI

NCT03879824
View directory record Official record
Conditions
Aortic Stenosis, Aortic Valve Disease, Vascular Access Complication
Interventions
Secondary Radial Artery Access, Secondary Femoral Artery Access
Procedure
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Traditional Lecture Versus Procedural Video

NCT05495282
View directory record Official record
Conditions
Educational Problems
Interventions
Microvideo
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
25 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 23, 2023 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Prehabilitative Exercise on Functional Recovery Following Total Knee Arthroplasty

NCT03227120
View directory record Official record
Conditions
Arthroplasty, Osteoarthritis, Knee
Interventions
Prehabilitation exercise
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
50 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2020 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional Results available

Robotic Hand Orthosis Providing Grasp Assistance for Patients With Brachial Plexus Injuries

NCT04939233
View directory record Official record
Conditions
Brachial Plexus Injury
Interventions
Exoskeleton glove
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 69 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

FitEx for Endometrial Cancer Survivors

NCT05233059
View directory record Official record
Conditions
Quality of Life, Cancer of Endometrium, Behavior, Health, Self Efficacy
Interventions
FitEx, Weekly Yoga Sessions, Weekly Movement Sessions
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 9, 2026, 2:29 AM EDT
Not listed Phase 2 Interventional

Methylene Blue as a Third-line Vasopressor in Septic Shock

NCT04089072
View directory record Official record
Conditions
Septic Shock
Interventions
Methylene Blue, Phenylephrine
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional

Effect of Music on Reading Comprehension in Patients With Aphasia

NCT03600987
View directory record Official record
Conditions
Aphasia
Interventions
Simultaneous music and reading lyrics, Priming with music, Control
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rocky Mount, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Oct 9, 2026, 2:29 AM EDT
Enrolling by invitation Not applicable Interventional

Low-Intensity Focused Ultrasound Neuromodulation for Epilepsy

NCT07353918
View directory record Official record
Conditions
Epilepsy (Treatment Refractory), Epilepsy Comorbidities
Interventions
Low-intensity Focused Ultrasound, Sham
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Phase 1 Interventional

Toradol (Ketorolac) in Breast Surgery to Reduce Pain & Opioid Use

NCT04439396
View directory record Official record
Conditions
Breast Reduction, Breast Reconstruction
Interventions
Ketorolac Tromethamine, Saline
Drug · Other
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 10, 2023 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional

Implementation and Evaluation of Measurement-Based Care (MBC) Training

NCT06386913
View directory record Official record
Conditions
Healthy
Interventions
Training
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 9, 2026, 2:29 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Inflammation and Medical Provider Attitudes, Cognition, and Treatment Decisions Study

NCT07842367
View directory record Official record
Conditions
Decision-Making, Patient Care, Treatment Decisions
Interventions
Influenza vaccine, Placebo
Biological · Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Fayetteville, Arkansas • Albuquerque, New Mexico • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional

Effect of Music on Reading Comprehension for Patients With Aphasia

NCT02875938
View directory record Official record
Conditions
Aphasia
Interventions
Simultaneous music and reading lyrics, Priming with music, Control
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rocky Mount, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2019 · Synced Oct 9, 2026, 2:29 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgeries

NCT04793022
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Orthopedic Disorder, Sports Injury, Anesthesia
Interventions
TIVA with Propofol, Inhaled Anesthesia
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional

Temporal Window and Episodic Future Thinking in CUD

NCT05507814
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Episodic Future Thinking (EFT), Control Episodic Thinking
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 9, 2026, 2:29 AM EDT
Not listed Not applicable Interventional

Theta Burst TMS for Treatment of Methamphetamine Use Disorder

NCT06372288
View directory record Official record
Conditions
Methamphetamine Abuse
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 9, 2026, 2:29 AM EDT
Not listed No phase listed Observational

Comparison of Standard SPECT vs xSPECT Reconstruction in the Clinical Management of Patients With Spinal Pain

NCT03702790
View directory record Official record
Conditions
Back Pain
Interventions
Not listed
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 9, 2026, 2:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Two Instruments for Stabilization of the Cervix During Office Procedures

NCT01769131
View directory record Official record
Conditions
Comparing Two Clamps for Mobilization of the Cervix During Common Gynecologic Office Procedures
Interventions
Not listed
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 9, 2026, 2:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Reach and Effectiveness of Technology-enhanced Diabetes Prevention Programs

NCT02162901
View directory record Official record
Conditions
Diabetes Prevention
Interventions
Choice-Class with IVR Calls, Random-Class with IVR calls, Random-Class only, Choice-DVD with IVR calls, Random-DVD with IVR calls
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
597 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 6, 2021 · Synced Oct 9, 2026, 2:29 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Combination 5-FU / Calcipotriene Cream for SCCIS/SCC

NCT04839731
View directory record Official record
Conditions
Squamous Cell Carcinoma
Interventions
Combination topical 5-fluorouracil 5% / calcipotriene 0.005% cream, Nourivan Base Cream
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 9, 2026, 2:29 AM EDT