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ClinicalTrials.gov public records Last synced Oct 9, 2026, 9:13 PM EDT

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Showing 49–72 of 839 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Children's Hospital Medical Center, Cincinnati Clear all
Completed Not applicable Interventional Results available

Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell Disease

NCT02200510
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Self-management intervention for Adolescents with SCD, Patient Portal Intervention for Adolescents with SCD
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 24 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 15, 2018 · Synced Oct 9, 2026, 9:13 PM EDT
Active, not recruiting No phase listed Observational

Personalizing Perioperative Analgesia in Children

NCT01140724
View directory record Official record
Conditions
Postoperative Pain
Interventions
Not listed
Lead sponsor
Senthil Sadhasivam
Other
Eligibility
3 Years to 15 Years
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 9, 2026, 9:13 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Engaging Adolescents in Decisions About Return of Genomic Research Results

NCT04481061
View directory record Official record
Conditions
Genetic Screening, Adolescent, Genetic Change, Shared Decision Making, Knowledge, Attitudes, Practice, Genetic Testing
Interventions
Electronic Decision Tool
Genetic
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 99 Years
Enrollment
787 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Rochester, Minnesota • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Oct 9, 2026, 9:13 PM EDT
Terminated Phase 3 Interventional Results available

AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department

NCT04669288
View directory record Official record
Conditions
Asthma, Wheezing
Interventions
Azithromycin, Placebo
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Months to 60 Months
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Phase 1 Interventional

A Pilot Study of the Addition of Bevacizumab to VOIT Regimen for Relapsed/Refractory Pediatric Solid Tumors

NCT00786669
View directory record Official record
Conditions
Solid Tumor
Interventions
Bevacizumab, Temozolomide, Vincristine, Irinotecan, Cefixime
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Year to 30 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Homes Healthy Children (H3C)

NCT01740622
View directory record Official record
Conditions
Injury in the Home
Interventions
Injury Prevention Measures
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Months to 36 Months
Enrollment
520 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 9, 2026, 9:13 PM EDT
Suspended Early Phase 1 Interventional

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

NCT05756660
View directory record Official record
Conditions
Ototoxicity, Drug-Induced
Interventions
Sodium Thiosulfate
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Month to 39 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 9, 2026, 9:13 PM EDT
Terminated Phase 1 Interventional

Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

NCT00272870
View directory record Official record
Conditions
Glioblastoma Multiforme (WHO Grade IV), Anaplastic Astrocytoma (WHO Grade III)
Interventions
06Benzylguanine, MGMT P140K, Meltenyi CliniMacs
Drug · Genetic · Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 55 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 29, 2012 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Not applicable Interventional

Supporting Treatment Adherence Regimens in Pediatric Epilepsy: The STAR Trial

NCT01851057
View directory record Official record
Conditions
Epilepsy
Interventions
STAR, Education Only
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
2 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 23, 2020 · Synced Oct 9, 2026, 9:13 PM EDT
Completed No phase listed Observational

Increased Liver Stiffness: A Study of Acoustic Radiation Force Impulse (ARFI) Elastography

NCT03382119
View directory record Official record
Conditions
Liver Fibroses
Interventions
Ultrasound with ARFI (acoustic radiation force impulse), Ultrasound with backscatter imaging
Device
Lead sponsor
University of Michigan
Other
Eligibility
2 Years to 5 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 9, 2026, 9:13 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Regional Phenotyping of CF and Non-CF Bronchiectasis

NCT04793867
View directory record Official record
Conditions
Cystic Fibrosis, Non-CF Bronchiectasis
Interventions
Xenon
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 9, 2026, 9:13 PM EDT
Terminated Phase 2 Interventional

Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant

NCT04908735
View directory record Official record
Conditions
Hematopoietic Stem Cell Transplant (HSCT), Bronchiolitis Obliterans (BO)
Interventions
Ruxolitinib
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Minneapolis, Minnesota • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 9, 2026, 9:13 PM EDT
Not yet recruiting Phase 4 Interventional

Semaglutide in Youth With Autism Spectrum Disorder

NCT07770152
View directory record Official record
Conditions
Autism Spectrum Disorder, Obesity
Interventions
Glucagon-like peptide-1 receptor agonist：Semaglutide, Lifestyle Management (LSM) Counseling
Drug · Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Phase 4 Interventional Results available

The Effects of ADHD Medication (TEAM) Study

NCT02293655
View directory record Official record
Conditions
ADHD
Interventions
OROS-Methylphenidate (MPH)
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 11 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Cincinnati, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 9, 2026, 9:13 PM EDT
Not listed Not applicable Interventional

I-InTERACT Preterm

NCT05282628
View directory record Official record
Conditions
Pre-Term
Interventions
Building Better Brains and Behavior program (B4 Preterm)
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
36 Months to 96 Months
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease

NCT05012631
View directory record Official record
Conditions
Sickle Cell Disease, Diffuse Myocardial Fibrosis
Interventions
Losartan
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Phase 2 Interventional Results available

A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas

NCT00634270
View directory record Official record
Conditions
Neurofibromatosis Type 1
Interventions
Sirolimus
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
3 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
9
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2017 · Synced Oct 9, 2026, 9:13 PM EDT
Completed No phase listed Observational

Parkinson's Research: The Organized Genetics Initiative

NCT00086073
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
Not listed
Enrollment
1,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2011
U.S. locations
52
States / cities
Phoenix, Arizona • Fountain Valley, California • Irvine, California + 43 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2011 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Not applicable Interventional Results available

Healthy Weight for Teens

NCT03939494
View directory record Official record
Conditions
Obesity
Interventions
Telehealth Encounter
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cincinnati, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Not applicable Interventional Results available

Diabetes Journey: An Adolescent Adherence Barriers Intervention

NCT04404556
View directory record Official record
Conditions
Type 1 Diabetes, Adherence, Patient
Interventions
Diabetes Journey, Enhanced Standard of Care
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 17 Years
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Gainesville, Florida • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Simultaneous mRNA COVID-19 and IIV4 Vaccination Study

NCT05028361
View directory record Official record
Conditions
Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
Interventions
mRNA COVID-19, IIV4, Placebo (saline)
Biological · Other
Lead sponsor
Duke University
Other
Eligibility
5 Years and older
Enrollment
348 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
3
States / cities
Baltimore, Maryland • Durham, North Carolina • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Oct 9, 2026, 9:13 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Intestinal Microbiome Composition in Infants With Biliary Atresia (BA)

NCT03890536
View directory record Official record
Conditions
Biliary Atresia, Intrahepatic Cholestases, Normal Controls
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day to 2 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2032
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Not applicable Interventional Results available

Clinical Use of a New Neonatal MRI System

NCT01801865
View directory record Official record
Conditions
Magnetic Resonance Imaging
Interventions
GE OPTIMA MR430s with HDX/GE Electronics
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
657 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Oct 9, 2026, 9:13 PM EDT
Completed Not applicable Interventional

Comparison of Two Different Pain Management Techniques in Pediatric Patients Undergoing a Hernia Repair

NCT01740193
View directory record Official record
Conditions
Pain, Inguinal Hernia
Interventions
TAP Block, Ilioinguinal/iliohypogastric blockade
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Months to 10 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 9, 2026, 9:13 PM EDT