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ClinicalTrials.gov public records Last synced Oct 10, 2026, 9:52 AM EDT

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Showing 49–72 of 97 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Joslin Diabetes Center Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

NCT03860558
View directory record Official record
Conditions
Overweight, Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus
Interventions
Lifestyle Intervention, No Intervention
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 10, 2026, 9:52 AM EDT
Completed No phase listed Observational

A Study of Technology to Improve Glucose Control in Participants With Type 1 Diabetes

NCT03758430
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Meal-Tagging App, Fitness Tracker
Other · Device
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2020 · Synced Oct 10, 2026, 9:52 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Physiology of Human Brown Adipose Tissue

NCT04352244
View directory record Official record
Conditions
Adipose Tissue, Brown, Adipose Tissue, Obesity
Interventions
Fat biopsy, Blood sampling, Blood sample for DNA analysis
Procedure · Diagnostic Test · Genetic
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional Results available

Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)

NCT05413239
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Psychoeducation to reduce diabetes distress and improve glycemic outcomes
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
14 Years to 25 Years
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Palo Alto, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 10, 2026, 9:52 AM EDT
Completed No phase listed Observational

PERL Continuous Glucose Monitoring (CGM) Study

NCT03334318
View directory record Official record
Conditions
Diabetic Nephropathies
Interventions
Mean blood glucose, Blood glucose CV, % time 70-180 mg/dL, % time below 54 mg/dL, % time above 180 mg/dL, % time above 250 mg/dL, MAGE (Mean amplitude of glucose excursions), LBGI (Low Blood Glucose Index), HBGI (High Blood Glucose Index), Allopurinol, Placebo
Other · Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
15
States / cities
Aurora, Colorado • Atlanta, Georgia • Chicago, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2022 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional Results available

Barriers to Adherence to Recommended Follow-up in Women With a History of Gestational Diabetes

NCT01681147
View directory record Official record
Conditions
Gestational Diabetes Mellitus
Interventions
2 online nutrition and exercise education classes, Self monitoring of blood glucose levels
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2023 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Exercise of Secreted Factors From Muscle and Adipose Tissue

NCT02565823
View directory record Official record
Conditions
Healthy
Interventions
Exercise bout
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 35 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2016 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood/Interstitial Glucose Measurements and Cognitive Function During Hypoglycemia and Recovery

NCT01283126
View directory record Official record
Conditions
Hypoglycemia
Interventions
euglycemic and hypoglycemic clamp
Procedure
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional Results available

Impact of a Virtual Diabetes Self-Care and Education Program on Diabetes-related Outcomes in Latinos With T2 Diabetes

NCT02488785
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Virtual Diabetes Self-Care and Education Program, Fitbit, Smartphone
Behavioral · Device
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 80 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Edinburg, Texas
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional

Optimizing Adherence and Glycemia in Youth With New Insulin-dependent Diabetes Mellitus (IDDM)

NCT00745342
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Family Teamwork Intervention
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
8 Years to 17 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional

Blood Glucose Awareness Training for Parents

NCT00315991
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Blood Glucose Awareness Training for Parents
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
6 Years to 11 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Boston, Massachusetts • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 16, 2013 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Targeting Inflammation Using Salsalate in CardioVascular Disease

NCT00624923
View directory record Official record
Conditions
Coronary Artery Disease, Overweight
Interventions
Salsalate, Placebo
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 75 Years
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
5
States / cities
York Village, Maine • Boston, Massachusetts • Framingham, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Oct 10, 2026, 9:52 AM EDT
Completed No phase listed Observational

Kidney Precision Medicine Project (KPMP) - COVID-19 Protocol

NCT05384899
View directory record Official record
Conditions
Acute Kidney Failure, Acute Kidney Insufficiency, Acute Renal Failure, Acute Renal Injury, Acute Renal Insufficiency, Kidney Failure, Acute, Kidney Insufficiency, Acute, Renal Failure, Acute, Renal Insufficiency, Acute, Covid19, Sars-CoV-2 Infection
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
New Haven, Connecticut • Baltimore, Maryland • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 10, 2026, 9:52 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Postnatal Exercise to Activate Baby's Brown Fat

NCT07467694
View directory record Official record
Conditions
Childhood Obesity Prevention, Childhood Obesity, Physical Activity, Lactation, Breastfeeding, Pregnancy, Exercise
Interventions
Active group
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post Bariatric Closed Loop Glucagon Trial

NCT02966275
View directory record Official record
Conditions
Hypoglycemia
Interventions
Glucagon-only bionic pancreas - glucagon, Glucagon-only bionic pancreas - placebo
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 13, 2018 · Synced Oct 10, 2026, 9:52 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life

NCT06141434
View directory record Official record
Conditions
Type 1 Diabetes, Pregnancy in Diabetic
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
0 Days to 99 Years
Enrollment
6,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2032
U.S. locations
4
States / cities
Aurora, Colorado • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 10, 2026, 9:52 AM EDT
Active, not recruiting Not applicable Interventional

The REST Study for CGM Use in Older Adults With Insulin-treated Diabetes

NCT05337826
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Continuous Glucose Monitor
Device
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
65 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Phase 3 Interventional Results available

A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes

NCT02017171
View directory record Official record
Conditions
Diabetic Nephropathies, Coronary Artery Disease
Interventions
Allopurinol, Placebo
Drug
Lead sponsor
Alessandro Doria
Other
Eligibility
18 Years to 70 Years
Enrollment
530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
23
States / cities
Aurora, Colorado • Denver, Colorado • Atlanta, Georgia + 15 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2020 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Salsalate Therapy to Reduce Insulin Resistance and Cardiovascular Risk

NCT00330733
View directory record Official record
Conditions
Atherosclerosis, Cardiovascular Disease, Inflammation, Insulin Resistance, Noninsulin-dependent Diabetes Mellitus
Interventions
Salsalate, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional

Evaluation of Fats on Postprandial Glucose Control

NCT01869790
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Different fat types
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Oct 10, 2026, 9:52 AM EDT
Recruiting Not applicable Interventional

Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics

NCT07271043
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
protein supplement
Dietary Supplement
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Phase 2 Interventional Results available

Metabolic Effects of Betaine Supplementation

NCT01950039
View directory record Official record
Conditions
Obesity, Dysglycemia
Interventions
Betaine, Placebo
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Oct 10, 2026, 9:52 AM EDT
Completed Not applicable Interventional Results available

OCT Screening for Diabetic Macular Edema at Primary Diabetes Care Visits

NCT01875783
View directory record Official record
Conditions
Diabetes, Diabetic Macular Edema, Diabetic Retinopathy
Interventions
OCT imaging
Device
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years and older
Enrollment
385 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
4
States / cities
Boston, Massachusetts • Wellfleet, Massachusetts • Syracuse, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2017 · Synced Oct 10, 2026, 9:52 AM EDT
Completed No phase listed Observational

Patient and Parent Preferences for an On-Body Automated Insulin Delivery System

NCT03534544
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Not listed
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
8 Years to 25 Years
Enrollment
362 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
New Haven, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 10, 2026, 9:52 AM EDT