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Showing 49–72 of 373 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Results available

Safety and Efficacy of CC-10004 for Prurigo Nodularis

NCT00869089
Conditions
Prurigo Nodularis
Interventions
CC-10004
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Multiple Myeloma
Interventions
Denosumab Q4W
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
7
States / cities
Atlanta, Georgia • Boston, Massachusetts • Danvers, Massachusetts + 3 more
Conditions
Heart Failure, Chronic Obstructive Pulmonary Disease
Interventions
Music Therapy
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
40 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
BPH, Erectile Dysfunction
Interventions
Alfuzosin 10 mg
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
45 Years to 75 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-nutritive Sweeteners in Inflammatory Bowel Disease

NCT07769437
Conditions
Inflamatory Bowel Disease, Crohn Disease (CD)
Interventions
Sucralose (non-nutritive sweetener)
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
3
States / cities
Chagrin Falls, Ohio • Cleveland, Ohio • Westlake, Ohio
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

NCT06096597
Conditions
Interstitial Cystitis, Painful Bladder Syndrome, Painful Bladder Syndrome (PBS)
Interventions
Clarix Flo, Placebo
Drug
Lead sponsor
David Sheyn
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Clevleand, Ohio
Conditions
Persistent Spinal Pain Syndrome
Interventions
Pain pump, Bupivacain 0.625%/Fentanyl 2mcg/ml, Spinal Cord Stimulator (SCS)
Device · Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
30 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Bipolar Disorder
Interventions
Psychoeducation module, Substance use module, Improved communication/rapport with provider module, Medication routines management module
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

BrightPoint Reflectometer Device Study

NCT05616299
Conditions
Epidural Placement
Interventions
BrightPoint
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 79 Years · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Violence, Domestic
Interventions
Couples Therapy, Control
Behavioral · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Ovarian Tissue Allo-transplantation

NCT06673004
Conditions
Ovarian Failure, Ovarian Insufficiency, Menopause Ovarian Failure, Menopause, Premature, Infertility, Female, Endocrine Female Infertility
Interventions
Ovarian tissue allo-transplantation
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
21 Years to 40 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Creutzfeldt-Jakob Disease (CJD) | Prion Disease
Interventions
Teleneurology Assessment
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Home BP Monitoring

NCT05552547
Conditions
High Blood Pressure
Interventions
Home Blood Pressure Machine, 24-Hour Blood Pressure Machine
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
13 Years to 18 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Completed No phase listed Observational Accepts healthy volunteers

Mitochondrial Biomarkers in Huntington's Disease

NCT04515550
Conditions
Huntington Disease
Interventions
lumbar puncture
Diagnostic Test
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
20 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Active, not recruiting Not applicable Interventional

PROSpect: Prone and Oscillation Pediatric Clinical Trial

NCT03896763
Conditions
Acute Respiratory Distress Syndrome in Children
Interventions
Either supine or prone positioning and either CMV or HFOV
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
2 Weeks to 20 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
28
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 24 more
Conditions
Crohn Disease
Interventions
Soy based diet, Non-soy based diet
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Human Immunodeficiency Virus (HIV), Vitamin D Deficiency, HIV Infections
Interventions
Vitamin D, Placebo
Drug · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Pain, Intractable, Breakthrough Pain, Chronic Pain
Interventions
Bupivacaine, Opioid
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
31 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Lung Nodule
Interventions
AI Based CAD Software (qXR-Ln)
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
44,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

A COmmunity and Tech-Based ApproaCh for Hypertension Self-MANagement

NCT03724487
Conditions
Hypertension, Self-management, Technology, Community-based Participatory Research
Interventions
Coachman, Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
30 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Artificial Intelligence (AI)
Interventions
Biometrics (or AI Biomaker)
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Terminated Phase 4 Interventional Results available

Pioglitazone for the Treatment of Bipolar Depression

NCT01717040
Conditions
Bipolar Disorder, Insulin Resistance
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Acute Pain, Surgery
Interventions
NeuroIDgenetix Test Panel
Other
Lead sponsor
AltheaDx
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Down Syndrome, Intellectual Disability, Alzheimer Dementia (AD)
Interventions
Memantine
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 32 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio