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ClinicalTrials.gov public records Last synced Oct 16, 2026, 8:27 PM EDT

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Showing 697–720 of 2,711 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Duke University Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

NCT00682695
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
7
States / cities
Chicago, Illinois • Louisville, Kentucky • Baltimore, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Study to Assess dHER2+AS15 Cancer Vaccine Given in Combination With Lapatinib to Patients With Metastatic Breast Cancer

NCT00952692
View directory record Official record
Conditions
Metastatic Breast Cancer
Interventions
dHER2 + AS15 ASCI, Lapatinib
Biological · Drug
Lead sponsor
Michael Morse, MD
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Not applicable Interventional

Exploring Beliefs and Behaviors About Weight Loss in Couples

NCT01777711
View directory record Official record
Conditions
Obesity
Interventions
Mental Contrasting- Individual, Mental Contrasting- Couple
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2014 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Phase I/II Study of Capecitabine Plus Aflibercept to Treat Metastatic Colorectal Cancer

NCT01661972
View directory record Official record
Conditions
Metastatic Colorectal Cancer
Interventions
Capecitabine and aflibercept
Drug
Lead sponsor
John Strickler, M.D.
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Durham, North Carolina • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 29, 2018 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 1 Interventional Results available

Safety Study of Lisinopril in Children and Adolescents With a Kidney Transplant

NCT01491919
View directory record Official record
Conditions
Hypertension
Interventions
Lisinopril
Drug
Lead sponsor
Uptal Patel
Other
Eligibility
2 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
7
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2015 · Synced Oct 16, 2026, 8:27 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

NCT05665465
View directory record Official record
Conditions
Adverse Childhood Experiences, Nicotine Dependence, Cigarettes
Interventions
Nicotine nasal spray 0.5 mg, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 21 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 3 Interventional

Standard Percutaneous Nephrolithotomy Percutaneous Nephrolithotomy (PNL) Versus Tubeless PNL Versus Tubeless Stentless PNL

NCT01548196
View directory record Official record
Conditions
Nephrolithotomy
Interventions
Standard Percutaneous nephrolithotomy
Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Oct 16, 2026, 8:27 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Labor Status Monitor for Diagnosing True vs False Labor in Preterm Patients

NCT06157203
View directory record Official record
Conditions
PreTerm Labor, Threatened Preterm Labor, Preterm Birth
Interventions
Uterine electromyography
Device
Lead sponsor
PreTeL, Inc
Industry
Eligibility
Female only
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Rochester, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Oct 16, 2026, 8:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mobile Neurofeedback for Low Back Pain

NCT05669027
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Neurofeedback, Sham (Placebo Control)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Not applicable Interventional

MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery

NCT01691742
View directory record Official record
Conditions
Post Procedural Constipation
Interventions
MiraLax, Placebo, Rescue Laxative
Drug
Lead sponsor
Duke University
Other
Eligibility
19 Years and older · Female only
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Oct 16, 2026, 8:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pulmonary Inflammation and Microbiome Changes With Bariatric Surgery in Obese Asthma

NCT04247971
View directory record Official record
Conditions
Asthma, Obesity
Interventions
Blood draw, Sputum collection, Pulmonary function test
Procedure
Lead sponsor
Duke University
Other
Eligibility
21 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 16, 2026, 8:27 PM EDT
Recruiting Phase 1Phase 2 Interventional

Asciminib in HER2+ Breast Cancer Brain Metastases

NCT07136428
View directory record Official record
Conditions
HER2+ Metastatic Breast Cancer
Interventions
Asciminib and Trastuzumab
Combination Product
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 2 Interventional

Low-Fat Diet and/or Flaxseed in Preventing Prostate Cancer

NCT00049309
View directory record Official record
Conditions
Prostate Cancer
Interventions
dietary intervention, flaxseed
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years to 120 Years · Male only
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
3
States / cities
Ann Arbor, Michigan • Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Not applicable Interventional

New Media Obesity Treatment in Community Health Centers

NCT01827800
View directory record Official record
Conditions
Obesity
Interventions
eHealth weight loss intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Oct 16, 2026, 8:27 PM EDT
Recruiting Not applicable Interventional

Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy

NCT06972719
View directory record Official record
Conditions
BRCA1 Mutation, BRCA2 Mutation
Interventions
Experimental Arm, SOC Arm
Behavioral
Lead sponsor
Duke University
Other
Eligibility
19 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 2 Interventional Results available

The Probiotic Study: Using Bacteria to Calm Your Mind

NCT02711800
View directory record Official record
Conditions
Anxiety, Abdominal Pain
Interventions
Lactobacillus rhamnosus
Drug
Lead sponsor
Nancy Zucker
Other
Eligibility
9 Years to 13 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 1 Interventional

Safety Study of Regorafenib With PF-03446962 to Treat Colorectal Cancer

NCT02116894
View directory record Official record
Conditions
Colorectal Cancer
Interventions
PF-03446962, Regorafenib
Biological · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Oct 16, 2026, 8:27 PM EDT
Completed No phase listed Observational

CTC Immune Checkpoint

NCT02456571
View directory record Official record
Conditions
Prostate Cancer
Interventions
CTC biomarker expression prevalence
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Male only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 1 Interventional

Use of ARINA-1 in an Intermediate Size Patient Population of Bilateral Lung Transplant Patients With CLAD Grade 0

NCT03226431
View directory record Official record
Conditions
Lung Transplant
Interventions
Ascorbic Acid
Drug
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Not applicable Interventional Results available

Inspiratory Muscle Rehabilitation in Children With Obesity

NCT05412134
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Pro2 - 75% of participant's MIP, Pro2 - 15% of participant's MIP
Device
Lead sponsor
Duke University
Other
Eligibility
8 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Phase 2 Interventional Results available

The Effects of Potassium on Glucose Metabolism in African Americans

NCT02236598
View directory record Official record
Conditions
Borderline Hypokalemia
Interventions
K+ supplement, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
30 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Oct 16, 2026, 8:27 PM EDT
Active, not recruiting Phase 2 Interventional

Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer

NCT04837209
View directory record Official record
Conditions
Breast Cancer, Triple Negative Breast Cancer
Interventions
Niraparib, Dostarlimab, Radiation therapy
Drug · Radiation
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 16, 2026, 8:27 PM EDT
Active, not recruiting No phase listed Observational

University of North Carolina Alumni Heart Study

NCT00005398
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Coronary Disease, Depression
Interventions
There is no intervention
Other
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
6,340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 16, 2026, 8:27 PM EDT
Completed Not applicable Interventional

Centers for Education on Research and Therapeutics - Heart Failure: Targeted Intervention Study

NCT00979264
View directory record Official record
Conditions
Heart Failure
Interventions
Intensive quality improvement tools
Behavioral
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 26, 2012 · Synced Oct 16, 2026, 8:27 PM EDT