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ClinicalTrials.gov public records Last synced Oct 15, 2026, 10:35 AM EDT

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Showing 697–720 of 872 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: University of Iowa Clear all
Completed Not applicable Interventional

Is Osteopathic Manipulative Treatment (OMT) Beneficial for Elderly Patients Hospitalized With Pneumonia?

NCT00258661
View directory record Official record
Conditions
Pneumonia
Interventions
Osteopathic Manipulative Treatment, Light-touch Treatment
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
50 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
7
States / cities
Mount Clemens, Michigan • Kirksville, Missouri • Stratford, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2018 · Synced Oct 15, 2026, 10:35 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

The Impact of Gestational Diabetes Mellitus on Cerebral Blood Flow and Cerebrovascular Function After Pregnancy

NCT06911372
View directory record Official record
Conditions
Gestational Diabetes Mellitus (GDM), Postpartum Women, Uncomplicated Pregnancy
Interventions
Intradermal Microdialysis, Brain Blood Flow Tests, Local Heating
Drug · Other
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 15, 2026, 10:35 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional Results available

TVEC and Preop Radiation for Sarcoma (8 ml Dose)

NCT04599062
View directory record Official record
Conditions
Soft Tissue Sarcoma
Interventions
Talimogene Laherparepvec, Radiotherapy
Drug · Radiation
Lead sponsor
John Rieth
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 15, 2026, 10:35 AM EDT
Active, not recruiting Early Phase 1 Interventional

Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)

NCT04634227
View directory record Official record
Conditions
Sarcoma, Soft Tissue Sarcoma, Unresectable Soft Tissue Sarcoma, Metastatic Bone Tumor, Bone Sarcoma
Interventions
Ascorbate
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 15, 2026, 10:35 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Azento IIS 3 Year Outcomes Implant Study

NCT04255342
View directory record Official record
Conditions
Tooth Loss
Interventions
Implant Placement and Temporary Crown using AstraTech Implant System EV, Final Crown Delivery
Device
Lead sponsor
Christopher Barwacz
Other
Eligibility
18 Years to 95 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

ProvodineTM Decreases Hand Contamination

NCT04023682
View directory record Official record
Conditions
Hand Hygiene
Interventions
Provodine Hand Sanitizer
Drug
Lead sponsor
Sundara Reddy
Other
Eligibility
22 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Oct 15, 2026, 10:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Psychological and Clinical Factors That Predict Intent to Deprescribe Medications Among Older Adults

NCT04676282
View directory record Official record
Conditions
Polypharmacy, Aging
Interventions
Hypothetical Scenario
Other
Lead sponsor
University of Michigan
Other
Eligibility
65 Years and older
Enrollment
10,184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Not applicable Interventional Results available

Ankle Foot Orthosis Comparative Effect

NCT03901053
View directory record Official record
Conditions
Foot Injuries and Disorders
Interventions
Reaktiv AFO, PhatBrace AFO
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Iowa City, Iowa • Bethesda, Maryland • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Not applicable Interventional Results available

Iterative Design of Custom Dynamic Orthoses

NCT04800510
View directory record Official record
Conditions
Adult ALL, Healthy
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 50 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Phase 1Phase 2 Interventional

Interpersonal Psychotherapy for Depression in People With Heart Failure

NCT00353223
View directory record Official record
Conditions
Depression, Heart Failure, Congestive
Interventions
Interpersonal and behavioral psychotherapy, Attention control (AC) condition
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
55 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Oct 15, 2026, 10:35 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Cabozantinib and Pembrolizumab for Advanced Metastatic Melanoma

NCT03957551
View directory record Official record
Conditions
Advanced Metastatic Melanoma
Interventions
Cabozantinib, Pembrolizumab
Drug
Lead sponsor
John Rieth
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Not applicable Interventional

Efficacy of Yoga for Postpartum Depression

NCT02213601
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Yoga
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 11, 2014 · Synced Oct 15, 2026, 10:35 AM EDT
Recruiting No phase listed Observational

Activity Levels in Bone Marrow Transplant Patients

NCT04115241
View directory record Official record
Conditions
Bone Marrow Transplant
Interventions
Actigraph, Grip strength test
Device · Other
Lead sponsor
Michael Tomasson
Other
Eligibility
18 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 15, 2026, 10:35 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab

NCT05363631
View directory record Official record
Conditions
Clear Cell Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma Metastatic
Interventions
Selenomethionine (SLM), Axitinib, Pembrolizumab
Drug
Lead sponsor
Mohammed Milhem
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 15, 2026, 10:35 AM EDT
Recruiting Phase 2 Interventional

177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry

NCT06395402
View directory record Official record
Conditions
Neuroendocrine Tumors, Neuroendocrine Tumor Grade 1, Neuroendocrine Tumor Grade 2
Interventions
Lutetium Lu 177 dotatate therapy
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Inhaled Cannabis on Driving Performance

NCT01620177
View directory record Official record
Conditions
Alcohol Drinking, Cannabis
Interventions
Alcohol(oral) and placebo, Cannabis(THC)(Inhaled) and Placebo
Drug
Lead sponsor
Gary R Gaffney
Other
Eligibility
21 Years to 55 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 15, 2026, 10:35 AM EDT
Recruiting No phase listed Observational

Quantitative MRI Assessment of Breast Cancer Therapy Response

NCT05704062
View directory record Official record
Conditions
Breast Cancer
Interventions
Diffusion Weighted Imaging, Dynamic Contrast-Enhanced Magnetic Resonance Imaging
Procedure
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
4
States / cities
Iowa City, Iowa • Royal Oak, Michigan • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Changes in the Feet With Pregnancy

NCT01868074
View directory record Official record
Conditions
Pregnancy
Interventions
Insole
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 2, 2016 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Not applicable Interventional Results available

Domperidone for the Treatment of Chronic Nausea and Vomiting Secondary to Gastroparesis

NCT01711918
View directory record Official record
Conditions
Patients With Gastroparesis Who Have Failed Standard Therapy
Interventions
Domperidone
Drug
Lead sponsor
Ron Schey
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 9, 2018 · Synced Oct 15, 2026, 10:35 AM EDT
Terminated Not applicable Interventional

Improving STEM Outcomes for Young Children With Language Learning Disabilities

NCT03438760
View directory record Official record
Conditions
Specific Language Impairment
Interventions
Science + Phonological Awareness, Science + Grammar Intervention, Science + Vocabulary Intervention
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
4 Years to 7 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Sep 14, 2020 · Synced Oct 15, 2026, 10:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MRI Assessing Clinical Usability of STrategically Acquired Gradient Echo on Human Participants

NCT04292301
View directory record Official record
Conditions
MRI
Interventions
STrategically Acquired Gradient Echo (STAGE)
Device
Lead sponsor
SpinTech, Inc.
Other
Eligibility
6 Years to 80 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
5
States / cities
Loma Linda, California • Los Gatos, California • Iowa City, Iowa + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 15, 2026, 10:35 AM EDT
Not yet recruiting Phase 3 Interventional Accepts healthy volunteers

Povidone Iodine for Caries Prevention

NCT07741409
View directory record Official record
Conditions
Dental Caries
Interventions
Povidone Iodine 5% Soln,Top,Kit, Probiotics, Placebo
Drug · Dietary Supplement
Lead sponsor
Jeffrey A. Banas
Other
Eligibility
1 Year to 3 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 15, 2026, 10:35 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation

NCT05330702
View directory record Official record
Conditions
Tooth Extraction, Immediate Implant Placement
Interventions
Xenogeneic Volume-Stable Collagen Matrix (VCMX) graft No Intervention: No Soft Tissue Augmentation, Tuberosity Connective Tissue Graft (CTG)
Device · Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 95 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 15, 2026, 10:35 AM EDT
Recruiting Phase 2 Interventional

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

NCT06405607
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence, Alcohol Abuse
Interventions
Psilocybin, Ketamine
Drug
Lead sponsor
University of Iowa
Other
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 28, 2025 · Synced Oct 15, 2026, 10:35 AM EDT