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ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:04 AM EDT

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Showing 721–744 of 2,711 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Duke University Clear all
Recruiting Phase 2 Interventional

Stool Transplants to Treat Refractory Clostridium Difficile Colitis

NCT02127398
View directory record Official record
Conditions
Clostridium Difficile Colitis
Interventions
fecal microbiota
Biological
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 3 Interventional Results available

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm D (Ivermectin 600)

NCT05894538
View directory record Official record
Conditions
Covid19
Interventions
Ivermectin, Placebo
Drug · Other
Lead sponsor
Susanna Naggie, MD
Other
Eligibility
30 Years and older
Enrollment
1,459 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
93
States / cities
Gilbert, Arizona • Mesa, Arizona • Peoria, Arizona + 81 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2023 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Not applicable Interventional Results available

Increasing Uptake of Behavioral Weight Loss Programs Among Primary Care Patients

NCT02708121
View directory record Official record
Conditions
Obesity
Interventions
Motivational Intervention, Comparator Intervention
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Oct 17, 2026, 6:04 AM EDT
Terminated Phase 2 Interventional Results available

Dose-Dense Induction/Neoadjuvant Chemotherapy in Locally Advanced Non-Small Cell Lung Cancer

NCT02157116
View directory record Official record
Conditions
Non-small Cell Lung Cancer
Interventions
cisplatin, Docetaxel, Pegfilgrastim
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 4, 2014 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Not applicable Interventional Results available

The Baerveldt Versus ClearPath Comparison Study

NCT04468633
View directory record Official record
Conditions
Glaucoma
Interventions
Baerveldt 350 implant, Ahmed ClearPath 350 implant
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 5, 2024 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding and Discouraging Overuse of Potentially Harmful Screening Tests

NCT01694784
View directory record Official record
Conditions
Preventive Screening, Prostate Cancer, Osteoporosis, Colorectal Cancer
Interventions
Quantitative Information Sheet, Qualitative Information Sheet, Narrative Information Sheet, Framed Information Sheet
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
50 Years to 85 Years
Enrollment
775 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 1 Interventional

Study of Cancer Peptides Vaccine Plus GM-CSF as Adjuvant Treatment for High Risk (TXN2-3M0) or Metastatic Breast Cancer With No Evidence of Disease

NCT00674791
View directory record Official record
Conditions
Breast Cancer
Interventions
OCPM Immunotherapeutic Vaccine
Biological
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 19, 2013 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 2Phase 3 Interventional

Quetiapine in Social Anxiety Disorder

NCT00215254
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
quetiapine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2006 · Synced Oct 17, 2026, 6:04 AM EDT
Active, not recruiting Not applicable Interventional Results available

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design

NCT02676973
View directory record Official record
Conditions
Visceral Prolapse
Interventions
Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
10
States / cities
Birmingham, Alabama • San Diego, California • Albuquerque, New Mexico + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Not applicable Interventional

Use of Technological Advances to Prevent Smoking Relapse Among Smokers With PTSD

NCT01990079
View directory record Official record
Conditions
PTSD, Smoking
Interventions
Bupropion, nicotine replacement therapy, Smoking cessation counseling, mobile contingency management, Stay Quit Coach
Drug · Other · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 4 Interventional

Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia

NCT00466388
View directory record Official record
Conditions
Xerostomia
Interventions
Cevimeline
Drug
Lead sponsor
American Academy of Otolaryngology-Head and Neck Surgery Foundation
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Colorado Springs, Colorado • Urbana, Illinois • Kansas City, Kansas + 4 more
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Emergency Department Re-evaluation Software Pilot Study

NCT05831046
View directory record Official record
Conditions
Emergency Department Waiting Room Congestion
Interventions
ED management software
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Connectivity-based rTMS and State-Dependency on Amygdala Activation

NCT03746405
View directory record Official record
Conditions
Amygdala Activation
Interventions
repetitive transcranial magnetic stimulation, Sham repetitive transcranial magnetic stimulation
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Results available

Belatacept Post Depletional Repopulation to Facilitate Tolerance

NCT00565773
View directory record Official record
Conditions
Organ Transplantation
Interventions
Belatacept, Sirolimus, Alemtuzumab
Drug
Lead sponsor
Allan D Kirk, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 17, 2026, 6:04 AM EDT
Active, not recruiting Phase 4 Interventional Results available

Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer

NCT05634720
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma
Interventions
HA Chemotherapy
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 17, 2026, 6:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1)

NCT03581227
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
CAPTURE Tool
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
45 Years to 80 Years
Enrollment
4,679 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
8
States / cities
Los Angeles, California • Aurora, Colorado • Miami, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2023 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 3 Interventional

Exercise Training Versus Drug Therapy for Treating Depression in Older Adults

NCT00331305
View directory record Official record
Conditions
Depression
Interventions
Supervised Exercise, Home-Based Exercise, Sertraline (Zoloft), Placebo Pill
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
40 Years and older
Enrollment
457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 29, 2013 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 1 Interventional Results available

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

NCT03043391
View directory record Official record
Conditions
Malignant Glioma, Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Glioblastoma, Gliosarcoma, Atypical Teratoid/Rhabdoid Tumor of Brain, Medulloblastoma, Ependymoma, Pleomorphic Xanthoastrocytoma of Brain, Embryonal Tumor of Brain
Interventions
Polio/Rhinovirus Recombinant (PVSRIPO)
Biological
Lead sponsor
Istari Oncology, Inc.
Industry
Eligibility
12 Years to 21 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 8, 2024 · Synced Oct 17, 2026, 6:04 AM EDT
Active, not recruiting Phase 2 Interventional

Botensilimab and Balstilimab Optimization in Colorectal Cancer

NCT06268015
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Botensilimab, Balstilimab, Oxaliplatin, Leucovorin, Fluorouracil, Bevacizumab, Panitumumab
Drug
Lead sponsor
Nicholas DeVito, MD
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 17, 2026, 6:04 AM EDT
Enrolling by invitation No phase listed Observational

FAST (Focused Abbreviated Screening Technique)-MRI Study

NCT04539717
View directory record Official record
Conditions
Hepatocellular Carcinoma (HCC), Liver Cirrhosis
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
820 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Los Angeles, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 17, 2026, 6:04 AM EDT
Terminated Phase 2 Interventional Results available

Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers

NCT02863068
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Topical Sodium Nitrite, Placebo
Drug · Other
Lead sponsor
caterina P minniti
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
The Bronx, New York • Durham, North Carolina • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Results available

Safety of Sildenafil in Premature Infants

NCT03142568
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Sildenafil, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Days to 28 Days
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
14
States / cities
Little Rock, Arkansas • Jacksonville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 4 Interventional Results available

Once-Daily Asenapine for Schizophrenia

NCT01549041
View directory record Official record
Conditions
Schizophrenia
Interventions
Asenapine 10 mg daily in the evening, Asenapine 5 mg twice daily
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Butner, North Carolina
Source: ClinicalTrials.gov public record
Updated May 26, 2014 · Synced Oct 17, 2026, 6:04 AM EDT
Completed Phase 1 Interventional Results available

IIT CTI Bendamustine, Rituximab, Pixantrone in Relapsed/Refractory B Cell Non-Hodgkin's Lymphoma

NCT01491841
View directory record Official record
Conditions
Non-Hodgkin's Lymphoma
Interventions
Bendamustine + Rituximab + Pixantrone, Pegfilgrastim
Drug
Lead sponsor
Anne Beaven, MD
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 17, 2026, 6:04 AM EDT