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ClinicalTrials.gov public records Last synced Oct 31, 2026, 10:02 PM EDT

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Showing 721–744 of 3,667 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Mayo Clinic Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)

NCT02223364
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Peripheral nerve blocks with Bupivacaine, Intra articular injection with Ropivacaine, Intra articular injection with liposomal bupivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Phase 1 Interventional

Minocycline in Primary Sclerosing Cholangitis (PSC)

NCT00630942
View directory record Official record
Conditions
Primary Sclerosing Cholangitis
Interventions
Minocycline
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 7, 2010 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Phase 1Phase 2 Interventional

A Study to Evaluate Platelet Rich Plasma to Treat Vulvar Lichen Sclerosus

NCT04967170
View directory record Official record
Conditions
Vulvar Lichen Sclerosus
Interventions
Autologous Platelet-Rich Plasma (PRP), Sham Procedure
Biological · Other
Lead sponsor
Jennifer R. Arthurs
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional

A Study of Soundscapes for Patient Wellbeing

NCT05650073
View directory record Official record
Conditions
Varicose Veins
Interventions
Immersive soundscapes
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Deciphering Preserved Autonomic Function After Spinal Cord Injury

NCT04493372
View directory record Official record
Conditions
Spinal Cord Injuries, Autonomic Imbalance, Autonomic Dysreflexia, Orthostatic Hypotension
Interventions
Tests of sympathetic inhibition, Tests of sympathetic activation, Testing of autonomic dysreflexia
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Standing on Glycemia in Prediabetic Adults

NCT01884792
View directory record Official record
Conditions
Prediabetes
Interventions
Sitting OGTT, Standing OGTT, Sitting CGM, Standing CGM
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 15, 2014 · Synced Oct 31, 2026, 10:02 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Lower Body Negative Pressure to Validate Physiological Monitors

NCT07840144
View directory record Official record
Conditions
Physiological Stress
Interventions
Lower Body Negative Pressure with Noninvasive Physiological Monitoring
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leptin Biology in Adipose Tissue

NCT01800864
View directory record Official record
Conditions
Obesity
Interventions
obesity
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 10, 2016 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional

A Study to Assess Metabolic Bone Disease of Prematurity Using an Acoustic Method

NCT04752098
View directory record Official record
Conditions
Metabolic Bone Disease, Osteopenia, Neonatal Rickets
Interventions
Vibro-acoustic analysis (VAA), based on ultrasound radiation force
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Days to 8 Months
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Early Phase 1 Interventional

Auranofin in Treating Patients With Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT01747798
View directory record Official record
Conditions
Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Primary Peritoneal Cavity Cancer
Interventions
auranofin, laboratory biomarker analysis
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 2, 2019 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional

A Study of Hemp Hull WFI for IBS Diarrhea

NCT06028035
View directory record Official record
Conditions
Irritable Bowel Syndrome-bile Acid Diarrhea
Interventions
BB01
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 31, 2026, 10:02 PM EDT
Recruiting Early Phase 1 Interventional

FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing Disease

NCT07460232
View directory record Official record
Conditions
Cushing Disease, Pituitary Adenoma
Interventions
Fluoro-O-(2) fluoroethyl-L-tyrosine (FET) PET
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 30, 2026 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessing a Endoscopic Mucosal Resection Site Using Different Endoscopic Imaging Methods

NCT02668198
View directory record Official record
Conditions
Post-endoscopic Mucosal Resection of Colon Polyps
Interventions
Olympus CF190 Colonoscope High definition white light, Olympus CF190 Colonoscope White light with near focus, Olympus CF190 Colonoscope Narrow band imaging, Olympus CF190 Colonoscope Narrow band imaging with near focus, Biopsy
Device · Procedure
Lead sponsor
Michael Wallace
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 17, 2019 · Synced Oct 31, 2026, 10:02 PM EDT
Recruiting Not applicable Interventional

Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?

NCT07454733
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Video recording, Notes Instruction
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
7
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Human Brain Natriuretic Peptide (BNP) (or Nesiritide) to Help Heart, Kidney and Humoral Function.

NCT00405548
View directory record Official record
Conditions
Left Ventricular Diastolic Dysfunction
Interventions
BNP (nesiritide), Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 1, 2015 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Evaluation of the Veriton SPECT/CT System

NCT04722185
View directory record Official record
Conditions
Focus of Study is Comparison of 2 Types of Gamma Cameras
Interventions
Veriton SPECT/CT
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Oct 31, 2026, 10:02 PM EDT
Not listed No phase listed Observational

Developing Prediction Models for Allograft Failure After Liver Transplantation

NCT05289609
View directory record Official record
Conditions
Liver Transplant Disorder
Interventions
Liver Transplantation
Procedure
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Los Angeles, California • Jacksonville, Florida • Worcester, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 31, 2026, 10:02 PM EDT
Terminated Not applicable Interventional

Surgical Versus Non-surgical Staging of Lung Cancer

NCT01117714
View directory record Official record
Conditions
Lung Cancer
Interventions
Integrated Staging for Early Detection of Metastases in Lung Cancer
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Jacksonville, Florida • Rochester, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Early Phase 1 Interventional

Safety and Feasibility of Kefir Administration in Critically Ill Adults

NCT05416814
View directory record Official record
Conditions
Critically Ill
Interventions
Kefir
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Oct 31, 2026, 10:02 PM EDT
Recruiting Not applicable Interventional

A Pilot Study to Assess the Safety, Tolerability, and Efficacy of Virtual Reality for the Treatment of Abdominal Pain in Quiescent Crohn's Disease

NCT06647615
View directory record Official record
Conditions
Crohn's Disease, Abdominal Pain (AP)
Interventions
VR headset
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility

NCT03286764
View directory record Official record
Conditions
Enhancement of the ADR During Colonoscopy
Interventions
Peppermint Oil, Distilled water
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis

NCT06316999
View directory record Official record
Conditions
Ulcerative Colitis, Pouchitis
Interventions
Intestinal Ultrasound
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 31, 2026, 10:02 PM EDT
Completed Phase 4 Interventional Results available

The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression.

NCT03156504
View directory record Official record
Conditions
Major Depression, Bipolar I Disorder, Bipolar II Disorder, Unipolar Depression
Interventions
Ketamine Hydrochloride
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
4
States / cities
Baltimore, Maryland • Ann Arbor, Michigan • Rochester, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Oct 31, 2026, 10:02 PM EDT
Terminated Not applicable Interventional

Remote Monitoring With Health-Coaching for Lifestyle Changes in Patients With Lung Cancer Related Fatigue

NCT05407038
View directory record Official record
Conditions
Advanced Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
Interventions
Exercise Counseling, Exercise Intervention, Internet-Based Intervention, Interview, Medical Device Usage and Evaluation, Questionnaire Administration
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 31, 2026, 10:02 PM EDT