Independent directory Public ClinicalTrials.gov records United States
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Showing 721–744 of 2,492 matching trials from the live ClinicalTrials.gov search.
Completed Phase 1 Interventional Accepts healthy volunteers

TransMEM Gas Exchange -- Project 1, Aim 2

NCT01925729
Conditions
Middle Ear Disease, Nasal Allergy
Interventions
ragweed, histamine, pseudoephedrine, Oxymetazoline
Biological · Drug
Lead sponsor
Cuneyt M. Alper
Other
Eligibility
18 Years to 50 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Exercise and Weight Loss on Cardiovascular Health

NCT01500356
Conditions
Cardiovascular Disease, Obesity
Interventions
Behavioral weight loss intervention, Diet Plus Moderate Exercise, Diet Plus High Exercise
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Kidney Transplant, Depression, Pain
Interventions
Collaborative care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 95 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Obesity, PreDiabetes, Aging
Interventions
DPP Intensive: 30-minute calls, DPP Support: 15-minute calls
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Cystic Fibrosis
Interventions
inhaled hypertonic saline (7%)
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Adenocarcinoma, Stomach Cancer
Interventions
mFLOFOX6 + pembrolizumab
Drug
Lead sponsor
Weijing Sun, MD, FACP
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Not listed No phase listed Observational Accepts healthy volunteers

Questionnaire Study to Assess Quality of Life After Treatment of Fibroids

NCT00390494
Conditions
Leiomyoma
Interventions
Hysterectomy, Myomectomy, Uterine Fibroid Embolization
Procedure
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
35 Years to 50 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Cleveland, Ohio • Pittsburgh, Pennsylvania
Conditions
SMN Complex Proteins, GEMIN5 Protein, Human, Neurodevelopmental Disorders
Interventions
GEMIN5-Related Neurodevelopmental Disorder
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2050
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Lower Extremity Weakness Distal, Distorted; Balance
Interventions
Assessment and education, Healthy Steps with Falls Case Management, Healthy Steps in Motion
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years to 100 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Evidence of Liver Transplantation
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Rheumatoid Arthritis
Interventions
Etanercept
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Total Knee Arthroplasty Postoperative Pain, Opioid Reduction After TKA
Interventions
NEUROCUPLE™ Patch, Sham patch, Enhanced Recovery After Surgery (ERAS) Standard of Care
Device · Other
Lead sponsor
Jacques E. Chelly
Other
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania
Recruiting Not applicable Interventional

tSCS in Children With Spina Bifida

NCT07615686
Conditions
Spina Bifida, Myelomeningocele
Interventions
Transcutaneous stimulator
Device
Lead sponsor
Bailey Petersen
Other
Eligibility
4 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Remimazolam NeuroImaging

NCT07290205
Conditions
Anesthesia, Pain, Remimazolam
Interventions
Remimazolam, Peripheral Nerve Stimulation
Drug · Device
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 59 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

The SleepTrackTXT2 Randomized Trial With Air-medical Personnel

NCT02783027
Conditions
Poor Quality Sleep, Fatigue
Interventions
SleepTrackTXT2
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Dementia, Alzheimer Disease
Interventions
multicomponent psychosocial intervention, Control arm
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
613 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
5
States / cities
Birmingham, Alabama • Menlo Park, California • Miami, Florida + 2 more
Conditions
Bacteremia, Pseudomonas Infections
Interventions
Blood draws, Blood draw
Procedure · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Acute Otitis Media (AOM), Upper Respiratory Infection
Interventions
Standard Clinical Ear Exam, AI app ear exam and diagnosis
Diagnostic Test
Lead sponsor
Timothy Shope
Other
Eligibility
6 Months to 24 Months
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease

NCT02162862
Conditions
Sleep Disturbance, Fatigue, Inflammatory Bowel Disease
Interventions
Behavioral Counseling, bupropion-SR
Behavioral · Drug
Lead sponsor
Eva Szigethy
Other
Eligibility
15 Years to 30 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Conditions
Post Lung Transplantation
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Myositis, Interstitial Lung Disease
Interventions
Abatacept, Placebo
Drug · Other
Lead sponsor
Rohit Aggarwal, MD
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
5
States / cities
Beverly Hills, California • Denver, Colorado • Baltimore, Maryland + 2 more
Conditions
Diabetes, Diabetic Foot, Diabetic Foot Ulcer, Diabetic Wound
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
6
States / cities
San Francisco, California • Stanford, California • Miami, Florida + 3 more
Conditions
Acute Lymphoblastic Leukemia
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
807 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Cardiomyopathy
Interventions
contrast-enhanced cardiac MRI
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania