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ClinicalTrials.gov public records Last synced Nov 1, 2026, 7:21 AM EST

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Showing 841–864 of 3,667 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Mayo Clinic Clear all
Not listed No phase listed Observational

KM3D Multicenter Cancer Consortium: Predicting Patient Response Using 3D Cell Culture Models

NCT05338073
View directory record Official record
Conditions
Cancer, Predictive Cancer Model, Effects of Chemotherapy
Interventions
Known 3Dx Test
Diagnostic Test
Lead sponsor
Known Medicine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Rochester, Minnesota • Durham, North Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Nov 1, 2026, 7:21 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women

NCT06743269
View directory record Official record
Conditions
Menopause, Hot Flashes, Blood Pressure Regulation
Interventions
High-Resistance Inspiratory Muscle Strength Training, Low-Resistance Inspiratory Muscle Strength Training, POWERbreathe K3 device
Behavioral · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Nov 1, 2026, 7:21 AM EST
Completed No phase listed Observational

SBRT for Oligometastatic Castration-Refractory Prostate Cancer

NCT02816983
View directory record Official record
Conditions
Prostate Cancer
Interventions
SBRT
Radiation
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Male only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Nov 1, 2026, 7:21 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Connecting Alaska Native People to Quit Smoking

NCT03645941
View directory record Official record
Conditions
Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Smoking Cessation, Smoking, Cigarette, Smoking, Tobacco, Smoking
Interventions
Facebook Group
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
19 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Nov 1, 2026, 7:21 AM EST
Completed Phase 1 Interventional

Safety Study of Chimeric Natriuretic Peptide(CD-NP) in Stable LVAD Patients

NCT01750905
View directory record Official record
Conditions
Left Ventricular Insufficiency
Interventions
CD-NP, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 30, 2016 · Synced Nov 1, 2026, 7:21 AM EST
Completed Phase 2Phase 3 Interventional

Cyrotherapy vs. APC in GAVE

NCT00587405
View directory record Official record
Conditions
Watermelon Stomach
Interventions
cryotherapy, Argon Plasma Coagulation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Nov 1, 2026, 7:21 AM EST
Completed Phase 4 Interventional

Diagnostic Accuracy of Capsule Endoscopy in Small Bowel Crohn's Disease

NCT00588653
View directory record Official record
Conditions
Crohn's Disease
Interventions
Capsule endoscopy, CT enterography, colonoscopy, small bowel follow-through
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 8, 2008 · Synced Nov 1, 2026, 7:21 AM EST
Recruiting Phase 2 Interventional

Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

NCT06635980
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Breast Carcinoma, Triple-Negative Breast Carcinoma
Interventions
Biopsy of Breast, Biospecimen Collection, Breast Surgery, Chemotherapy, Computed Tomography, Contrast Enhanced Digital Mammography, Hypofractionated Radiation Therapy, Magnetic Resonance Imaging, Positron Emission Tomography, Survey Administration, Tissue Collection, Ultrasound Imaging
Procedure · Drug · Radiation + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Nov 1, 2026, 7:21 AM EST
Completed Not applicable Interventional Results available

Visual and Electromyography Assessments in Response to Train-of-Four Stimulation of the Ulnar Nerve

NCT04352127
View directory record Official record
Conditions
Residual Neuromuscular Blockade
Interventions
TetraGraph
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Nov 1, 2026, 7:21 AM EST
Completed Phase 2Phase 3 Interventional Results available

Patient-Directed Postoperative Opioid Prescribing for Gynecologic Surgery

NCT03805386
View directory record Official record
Conditions
Gynecology, Surgery, Opioid Use
Interventions
Physician directed opioid prescribing, Patient directed opioid prescribing
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Nov 1, 2026, 7:21 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Exercise Intervention on Various Physiologic Factors That Change With Increasing Age

NCT00283673
View directory record Official record
Conditions
Aging
Interventions
Exercise
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 90 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995 – 1998
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 6, 2011 · Synced Nov 1, 2026, 7:21 AM EST
Terminated No phase listed Observational

Human Mesenchymal Stem Cells in the Synovial Fluid of the Hip

NCT02941666
View directory record Official record
Conditions
Osteonecrosis
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 12, 2022 · Synced Nov 1, 2026, 7:21 AM EST
Recruiting Not applicable Interventional

High Resolution Gastric Mapping and Gastroduodenal Manometry

NCT06941545
View directory record Official record
Conditions
Dyspepsia
Interventions
Alimetry, tVNS, Gastroduodenal Manometry
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Nov 1, 2026, 7:21 AM EST
Completed Phase 1Phase 2 Interventional Results available

Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery

NCT02730546
View directory record Official record
Conditions
Gastric Cardia Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Stage IB Gastric Cancer AJCC v7, Stage II Gastric Cancer AJCC v7, Stage IIA Gastric Cancer AJCC v7, Stage IIB Gastric Cancer AJCC v7, Stage IIIA Gastric Cancer AJCC v7, Stage IIIB Gastric Cancer AJCC v7
Interventions
Carboplatin, Computed Tomography, Fluorouracil, Laboratory Biomarker Analysis, Leucovorin Calcium, Oxaliplatin, Paclitaxel, Pembrolizumab, Positron Emission Tomography, Radiation Therapy, Therapeutic Conventional Surgery
Drug · Procedure · Other + 2 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
2
States / cities
Phoenix, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Nov 1, 2026, 7:21 AM EST
Active, not recruiting Phase 2 Interventional

Allogeneic BM-MSCs in Patients With Painful Lumbar Facet Arthropathy

NCT06001853
View directory record Official record
Conditions
Facet-Mediated Low Back Pain, Lumbar Facet Joint Osteoarthritis
Interventions
BM-MSC injection, DSMO Injection
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Nov 1, 2026, 7:21 AM EST
Completed Phase 1 Interventional Accepts healthy volunteers

The Impact of Proton Pump Inhibitors on the Fecal Microbiome

NCT01822977
View directory record Official record
Conditions
Healthy, Clostridium Difficile Infection
Interventions
omeprazole
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Nov 1, 2026, 7:21 AM EST
Recruiting No phase listed Observational

Gynecologic Extramammary Paget's Disease

NCT03564483
View directory record Official record
Conditions
Extramammary Paget's Disease, Extramammary Paget Disease, Paget Disease, Extramammary, Extramammary Paget's Disease of Vulva (Diagnosis), Extramammary Paget's Disease of Vagina (Diagnosis), Extramammary Paget's Disease Vulva Invasive, Extramammary Paget's Disease of Anus (Diagnosis), Extramammary Paget's Disease of Anal Canal (Diagnosis), Extramammary Paget's Disease of Skin
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2050
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Nov 1, 2026, 7:21 AM EST
Completed Not applicable Interventional

Enhancement of Contrast Opacification for Echocardiographic Imaging of the Right Heart and Shunts

NCT02661529
View directory record Official record
Conditions
Bidirectional Cardiovascular Shunt
Interventions
Transesophageal Echocardiogram (TEE), Transthoracic Echocardiogram (TTE), Saline/Air Mixture, Saline/Blood Mixture
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 105 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Nov 1, 2026, 7:21 AM EST
Completed No phase listed Observational

Evaluation of the BodyGuardian End-to-end Remote Monitoring Platform in an Outpatient Heart Failure Population

NCT01975402
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
3
States / cities
Jacksonville, Florida • Eau Claire, Wisconsin • La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Nov 1, 2026, 7:21 AM EST
Completed No phase listed Observational

Ventricular and Pulmonary Vascular Reserve After the Fontan Operation

NCT03853837
View directory record Official record
Conditions
Heart Failure, Congenital Heart Disease
Interventions
rest-exercise echocardiography
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Nov 1, 2026, 7:21 AM EST
Completed Phase 1Phase 2 Interventional Results available

Botulin-A Toxin Instillations and Overactive Bladder

NCT00583219
View directory record Official record
Conditions
Overactive Bladder, Detrusor Instability, Detrusor Hyperreflexia
Interventions
Botulinum-A toxin, Dimethyl sulfoxide (DMSO)
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 21, 2014 · Synced Nov 1, 2026, 7:21 AM EST
Completed No phase listed Observational Accepts healthy volunteers

A Study of Cardiovascular Disease Awareness and Cardiovascular Health

NCT06523972
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Health
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
387 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Nov 1, 2026, 7:21 AM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Determining How Indoor Lighting Affects the Brain Health of Older Adults

NCT05978934
View directory record Official record
Conditions
Sleep, Physical Activity, Cognitive Function, Social Isolation
Interventions
Static Lighting Condition (L1), Dynamic Lighting Condition (L2), Dynamic Lighting Condition (L3)
Behavioral
Lead sponsor
Well Living Lab, Inc.
Industry
Eligibility
60 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Nov 1, 2026, 7:21 AM EST
Recruiting Not applicable Interventional

Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions

NCT04047264
View directory record Official record
Conditions
Glioma, Glioblastoma, Metastatic Malignant Neoplasm in the Brain
Interventions
Microdialysis, Magnetic Resonance Imaging, Computed Tomography
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Nov 1, 2026, 7:21 AM EST