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ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:12 PM EDT

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Showing 73–96 of 397 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Alcon Research Clear all
Completed Not applicable Interventional Results available

Acute Comfort and Blur of Systane Ultra and Systane

NCT00748865
View directory record Official record
Conditions
Dry Eye
Interventions
Systane Ultra Lubricant Eye Drops, Systane Lubricant Eye Drops
Other
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2012 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses

NCT05886907
View directory record Official record
Conditions
Refractive Errors, Presbyopia, Astigmatism
Interventions
Lehfilcon A multifocal toric contact lenses, Samfilcon A multifocal toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Oct 17, 2026, 9:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Eye Drop Use in Glaucoma Patients Through Patient Surveys and Video Observations

NCT00522600
View directory record Official record
Conditions
Glaucoma, Dry Eye Syndrome, Conjunctivitis
Interventions
Not listed
Lead sponsor
Robin, Alan L., M.D.
Individual
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 22, 2009 · Synced Oct 17, 2026, 9:12 PM EDT
Terminated Phase 3 Interventional

Anecortave Acetate Risk-Reduction Trial (AART)

NCT00333216
View directory record Official record
Conditions
AMD
Interventions
Anecortave Acetate Sterile Suspension, 30 mg/mL, Anecortave Acetate Sterile Suspension, 60 mg/ML, Anecortave Acetate Vehicle
Drug · Other
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Oct 17, 2026, 9:12 PM EDT
Terminated Not applicable Interventional Results available

Post Approval Study of the CyPass System

NCT03273907
View directory record Official record
Conditions
Primary Open-angle Glaucoma, Cataract
Interventions
CyPass Micro-Stent implanted with CyPass 241-S applier, Cataract surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
45 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
20
States / cities
Phoenix, Arizona • Orange, California • Fort Collins, Colorado + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2024 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Phase 4 Interventional Results available

ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens (IOL)

NCT00684138
View directory record Official record
Conditions
Cataract
Interventions
ACRYSOF® ReSTOR® Aspheric +4.0 D Add Power Intraocular Lens, ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2010 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses

NCT05959200
View directory record Official record
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism
Interventions
Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 17, 2026, 9:12 PM EDT
Withdrawn Phase 4 Interventional

Comparison of Corneal Aberrations and Visual Outcomes in AcrySof IQ Toric Patients Versus Limbal Relaxing Incision (LRI) Patients

NCT00929747
View directory record Official record
Conditions
Cataracts
Interventions
Toric, Limbal Relaxing Incision
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2012 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia

NCT01028378
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
T-CAT topography-guided LASIK treatment with the Allegretto Wave Eye-Q 400 Hz Excimer Laser
Device
Lead sponsor
Clinical Research Consultants, Inc.
Industry
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
10
States / cities
La Quinta, California • San Diego, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2016 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Performance Assessment of a Modified Daily Disposable Contact Lens

NCT03762668
View directory record Official record
Conditions
Refractive Errors, Myopia, Hyperopia
Interventions
Modified delefilcon A contact lenses, Delefilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
5
States / cities
Maitland, Florida • Orlando, Florida • West Palm Beach, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Corneal Barrier Function With Multi-Purpose Solutions

NCT00407238
View directory record Official record
Conditions
Contact Lens Care
Interventions
Multi-purpose solutions (polyquaternium-1 and PHMB)
Device
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2007 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent

NCT04629521
View directory record Official record
Conditions
Primary Open Angle Glaucoma, Cataract
Interventions
CyPass Micro-Stent, Cataract Surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
45 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
12
States / cities
Glendale, Arizona • Orange, California • Fort Collins, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Phase 3 Interventional Results available

Safety Study of Olopatadine Nasal Spray

NCT00578331
View directory record Official record
Conditions
Perennial Allergic Rhinitis
Interventions
Olopatadine 0.6% nasal spray, Placebo Nasal Spray
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
12 Years and older
Enrollment
890 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Oct 31, 2017 · Synced Oct 17, 2026, 9:12 PM EDT
Recruiting Not applicable Interventional

Hydrus® Microstent New Enrollment Post-Approval Study

NCT04553523
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
Hydrus Microstent, Cataract surgery, Monofocal IOL
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
45 Years and older
Enrollment
545 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
22
States / cities
Irvine, California • Sacramento, California • Loveland, Colorado + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 17, 2026, 9:12 PM EDT
Recruiting Phase 4 Interventional

Adaptive Optics OCT Evaluation of Rhopressa's Effects on the Retinal Ganglion Cells in Glaucoma Patients

NCT07847073
View directory record Official record
Conditions
Open Angle Glaucoma (OAG), Glaucoma
Interventions
Netarsudil 0.02% Ophthalmic Solution [RHOPRESSA], Timolol Maleate 0.25% Ophthalmic Solution
Drug
Lead sponsor
Brett King
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Phase 3 Interventional

An Evaluation of Safety and Efficacy of Anecortave Acetate Versus Placebo in Patients With Subfoveal CNV Due to Exudative AMD

NCT00058994
View directory record Official record
Conditions
Macular Degeneration, Maculopathy, Age-Related
Interventions
anecortave acetate
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Oct 17, 2026, 9:12 PM EDT
Completed No phase listed Observational Results available

Surgeon Experience ReSTOR A +4 Intraocular Lens (IOL)

NCT00733512
View directory record Official record
Conditions
Cataract
Interventions
ReSTOR
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Oct 17, 2026, 9:12 PM EDT
Recruiting Phase 4 Interventional

Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects

NCT04401982
View directory record Official record
Conditions
Ocular Hypertension, Suspect Glaucoma
Interventions
Rocklatan (Netarsudil 0.02%/ latanoprost 0.005), Latanoprost (0.005%)
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Baltimore, Maryland • Columbia, Maryland • Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens

NCT04631796
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Multipurpose disinfection solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
3
States / cities
Orlando, Florida • Bloomington, Illinois • Powell, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 1

NCT04527978
View directory record Official record
Conditions
Refractive Errors, Myopia
Interventions
Verofilcon A contact lenses, Nesofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
4
States / cities
Maitland, Florida • Medina, Minnesota • Powell, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of Two Reusable Silicone Hydrogel Contact Lenses

NCT05050578
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
10
States / cities
Oakland, California • San Francisco, California • Longwood, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of Two Daily Disposable Contact Lenses - Pilot Study 3

NCT04942925
View directory record Official record
Conditions
Myopia, Ametropia
Interventions
Verofilcon A contact lenses, Kalifilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
4
States / cities
Maitland, Florida • Orlando, Florida • Eden Prairie, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers

NCT03585790
View directory record Official record
Conditions
Asthenopia, Myopia
Interventions
Contact lens with Multifocal Optics, Contact lens with Single Vision Optics
Device
Lead sponsor
Pete Kollbaum, OD, PhD
Other
Eligibility
18 Years to 35 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 7, 2020 · Synced Oct 17, 2026, 9:12 PM EDT
Completed Phase 4 Interventional Results available

Safety and Efficacy of Changing to DuoTrav in Patients Uncontrolled on Timolol

NCT01336569
View directory record Official record
Conditions
Glaucoma
Interventions
Travoprost 0.004%/timolol maleate 0.5% fixed combination
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2013 · Synced Oct 17, 2026, 9:12 PM EDT