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ClinicalTrials.gov public records Last synced Oct 12, 2026, 10:37 PM EDT

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Showing 73–96 of 778 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Children's Hospital of Philadelphia Clear all
Completed No phase listed Observational

Clinical Evaluation of PROMIS in CKD

NCT03842293
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 21 Years
Enrollment
213 participants
Timeline
2017 – 2020
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • Atlanta, Georgia + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2020 · Synced Oct 12, 2026, 10:37 PM EDT
Terminated Phase 3 Interventional Results available

Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair

NCT02075411
View directory record Official record
Conditions
Injury of Anterior Cruciate Ligament
Interventions
bupivacaine, continuous perineural infusion catheter
Drug · Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
14 Years to 18 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Not applicable Interventional

A Pilot Study to Measure Blood Levels of Desflurane in Children

NCT00577369
View directory record Official record
Conditions
Desflurane Levels
Interventions
Desflurane Levels
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 18 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2009 · Synced Oct 12, 2026, 10:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Cerebral Blood Flow and Childhood Obstructive Sleep Apnea

NCT02995837
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Sleep Study, Neurocognitive Testing, CBF During Wakefulness, CBF During Sleep
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 12 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 12, 2026, 10:37 PM EDT
Completed No phase listed Observational

VIRTUUS Children's Study

NCT03719339
View directory record Official record
Conditions
Renal Transplant Rejection, Pediatric Kidney Disease, End Stage Renal Disease, Nephropathy, BK Virus (Nephropathy), Antibody-mediated Rejection, Acute Cellular Graft Rejection
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 18 Years
Enrollment
445 participants
Timeline
2017 – 2026
U.S. locations
12
States / cities
La Jolla, California • Los Angeles, California • Palo Alto, California + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Sirolimus for Autoimmune Disease of Blood Cells

NCT00392951
View directory record Official record
Conditions
Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS), Evans Syndrome, Idiopathic Thrombocytopenic Purpura, Anemia, Hemolytic, Autoimmune, Autoimmune Neutropenia, Lupus Erythematosus, Systemic, Inflammatory Bowel Disease, Rheumatoid Arthritis
Interventions
sirolimus
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 30 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 12, 2026, 10:37 PM EDT
Recruiting Phase 1 Interventional

Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention

NCT07084129
View directory record Official record
Conditions
Sepsis
Interventions
personalized dosing adjustment of vancomycin
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Month to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Not applicable Interventional Results available

Crohn Disease Exclusion Diet After Single Medication De-escalation

NCT02472457
View directory record Official record
Conditions
Crohn Disease
Interventions
Crohn Disease Exclusion Diet, Free Diet
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
10 Years to 21 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 12, 2026, 10:37 PM EDT
Recruiting Not applicable Interventional

Vancomycin Reduction Practices (VRP) in the NICU

NCT06772675
View directory record Official record
Conditions
Antibiotic Stewardship, Neonatal Sepsis, Late-Onset, Vancomycin
Interventions
External Facilitation
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
13
States / cities
Modesto, California • Oakland, California • Roseville, California + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 12, 2026, 10:37 PM EDT
Completed No phase listed Observational

Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT

NCT01203085
View directory record Official record
Conditions
Charcot Marie Tooth Disease
Interventions
Not listed
Lead sponsor
University of Iowa
Other
Eligibility
Up to 21 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2025
U.S. locations
9
States / cities
Palo Alto, California • Hartford, Connecticut • Orlando, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Phase 2 Interventional Results available

Intranasal Oxytocin in Hypothalamic Obesity

NCT02849743
View directory record Official record
Conditions
Craniopharyngioma, Hypothalamic Obesity
Interventions
Syntocinon, Placebo (for Syntocinon)
Drug
Lead sponsor
Shana McCormack, MD
Other
Eligibility
10 Years to 35 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Oct 12, 2026, 10:37 PM EDT
Withdrawn Not applicable Interventional

Pulmonary Assessment in Thoracic Insufficiency Syndrome Patients

NCT04977830
View directory record Official record
Conditions
Thoracic Insufficiency Syndrome
Interventions
Xenon-129
Device
Lead sponsor
Patrick Cahill, MD
Other
Eligibility
6 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

eCEASE to Support Treatment for Parental Tobacco Use

NCT04974736
View directory record Official record
Conditions
Tobacco Smoking, Second Hand Tobacco Smoke, Smoking Cessation
Interventions
iEHR + Navigator
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
817 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Not applicable Interventional Results available

Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies

NCT02323867
View directory record Official record
Conditions
Leukemia, Lymphoma, Myelodysplasia
Interventions
CliniMACS α/β T-Cell and CD19+ B-Cell Depleted Peripheral Blood Stem Cell Transplant
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 23 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 12, 2026, 10:37 PM EDT
Active, not recruiting No phase listed Observational

Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease

NCT05707663
View directory record Official record
Conditions
Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
Interventions
Not listed
Lead sponsor
University of Iowa
Other
Eligibility
4 Years to 30 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
5
States / cities
Sacramento, California • Iowa City, Iowa • Philadelphia, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 12, 2026, 10:37 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Pennsylvania Adolescent Intervention Research Study (PAIRStudy)

NCT00329199
View directory record Official record
Conditions
Depression
Interventions
Attachment-Based Family Therapy
Behavioral
Lead sponsor
Pennsylvania Department of Health
Government
Eligibility
12 Years to 18 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
3
States / cities
Allentown, Pennsylvania • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2007 · Synced Oct 12, 2026, 10:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurocognitive Outcomes and Quality of Life in Adults With Maple Syrup Urine Disease (MSUD)

NCT04828863
View directory record Official record
Conditions
Maple Syrup Urine Disease
Interventions
Neurocognitive testing
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
21 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Not applicable Interventional

Initial Evaluation of the Cellie Coping Kit for Children With Injury

NCT03153696
View directory record Official record
Conditions
Injuries
Interventions
Cellie Coping Kit Intervention
Behavioral
Lead sponsor
Meghan Marsac
Other
Eligibility
8 Years to 12 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Oct 12, 2026, 10:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Driver Education Research Study

NCT06413927
View directory record Official record
Conditions
Risk Reduction Behavior, Injuries, Accident, Traffic, Development, Adolescent
Interventions
Online Vehicle and Driver Safety Education, Online Driver Skills Training, Behind-the-Wheel Driver Training
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
16 Years to 17 Years
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 12, 2026, 10:37 PM EDT
Recruiting Phase 1 Interventional

Anti-CD7 CAR-T Cells in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia or Lymphoma

NCT06934382
View directory record Official record
Conditions
T-Cell Acute Lymphoblastic Leukemia/Lymphoma
Interventions
Allogeneic anti-CD7 CAR-T cells (BEAM-201)
Biological
Lead sponsor
Stephan Grupp MD PhD
Other
Eligibility
0 Years to 29 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Decision Aid for Education and Support About Cancer Treatment

NCT06191679
View directory record Official record
Conditions
Cancer, Childhood Cancer
Interventions
Decision Aid for Education and Support about Cancer Treatment (DECIDES Intervention)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
15 Years to 24 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Oct 12, 2026, 10:37 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Neurophysiologic Biomarkers in Rett Syndrome

NCT05932589
View directory record Official record
Conditions
Rett Syndrome, RTT, Rett Syndrome, Atypical
Interventions
EEG and Auditory and Visual Evoked Potentials (AEP and VEP), Clinical assessment
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Year to 18 Years · Female only
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
6
States / cities
Los Angeles, California • Aurora, Colorado • Brookline, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 12, 2026, 10:37 PM EDT
Completed Not applicable Interventional Results available

Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit

NCT03749330
View directory record Official record
Conditions
Communication, Critical Illness
Interventions
CICU Team And Loved Ones Communicating (CICU TALC)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 12, 2026, 10:37 PM EDT
Enrolling by invitation Not applicable Interventional

ESG in Obese Adolescents

NCT06914765
View directory record Official record
Conditions
Obese Adolescents, Obesity, Morbid, Obesity/Therapy
Interventions
Endoscopic Sleeve Gastroplasty (ESG) Procedure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 12, 2026, 10:37 PM EDT