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ClinicalTrials.gov public records Last synced Oct 10, 2026, 1:28 PM EDT

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Showing 73–96 of 97 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Joslin Diabetes Center Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Exercise Training-Induced Myokines and Adipolkines in Humans

NCT03037216
View directory record Official record
Conditions
Healthy
Interventions
Exercise Intervention
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 10, 2026, 1:28 PM EDT
Recruiting No phase listed Observational

Kidney Precision Medicine Project

NCT04334707
View directory record Official record
Conditions
Acute Kidney Failure, Acute Kidney Insufficiency, Acute Renal Failure, Acute Renal Injury, Acute Renal Insufficiency, Kidney Failure, Acute, Kidney Insufficiency, Acute, Renal Failure, Acute, Renal Insufficiency, Acute, Chronic Kidney Diseases, Chronic Kidney Insufficiency, Chronic Renal Diseases, Chronic Renal Insufficiency, Kidney Insufficiency, Chronic, Type 1 Diabetes (T1D)
Interventions
Kidney Biopsy, MRI, Retina Scan
Procedure · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
13
States / cities
Tucson, Arizona • New Haven, Connecticut • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Phase 4 Interventional Results available

Simplified Insulin Protocol Using Lantus in Elderly

NCT01480843
View directory record Official record
Conditions
Diabetes
Interventions
Glargine
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
70 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Oct 10, 2026, 1:28 PM EDT
Active, not recruiting No phase listed Observational

Hypoglycemia and the Gut Microbiome

NCT03385707
View directory record Official record
Conditions
Hypoglycemia
Interventions
Not listed
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Not applicable Interventional Results available

Continuous Glucose Monitoring to Reduce Hypoglycemia and Improve Safety After Gastric Surgery

NCT03353415
View directory record Official record
Conditions
Hypoglycemia, Reactive, Hypoglycemia
Interventions
Dexcom CGM masked, Dexcom CGM unmasked
Device
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Oct 10, 2026, 1:28 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Mechanisms of Hypoglycemia in Patients Without Diabetes

NCT04428723
View directory record Official record
Conditions
Hypoglycemia
Interventions
Entry of demographic and medical history data into a deidentified database, Blood sample for DNA analysis, Stool sample for microbiome analysis, Mixed meal tolerance test, Continuous glucose monitoring, activity monitor
Other · Genetic · Diagnostic Test
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Not applicable Interventional

The Effect of 3 Different Models of MNT on DM Control in Overweight Patients With T2DM

NCT02520050
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Traditional MNT, Structured MNT, Structured MNT plus Weekly Support
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
30 Years to 80 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Enhancement of Cerebral Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes

NCT01206322
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Intranasal insulin, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Oct 10, 2026, 1:28 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Mechanisms of Post-Bariatric Hypoglycemia

NCT04428866
View directory record Official record
Conditions
Hypoglycemia
Interventions
Continuous Glucose Monitoring, activity monitor, Mixed meal tolerance test, Glucagon Sensitivity Testing, Hypoglycemic Hyperinsulinemic Clamp, analysis of fecal microbiome
Diagnostic Test
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Changes in Inflammatory State in Asian Americans Changing From Traditional Asian Diets to American Diet - a Pilot Study

NCT00379548
View directory record Official record
Conditions
Diabetes, Insulin Resistance, Inflammation, Cardiovascular Disease, Periodontal Disease
Interventions
2 groups of population responding to 2 types of diets
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
25 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Not applicable Interventional

Hypoglycaemia Awareness Restoration Programme

NCT02940873
View directory record Official record
Conditions
Type 1 Diabetes Mellitus, Hypoglycemia
Interventions
HARPdoc courses, BGAT courses
Behavioral
Lead sponsor
King's College London
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2021 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Not applicable Interventional

Using Conversation Maps to Reinforce Self-Care

NCT00895986
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Conversation Maps Diabetes Education, Heart Healthy Living Diabetes Education
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
25 Years to 75 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2012 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Phase 4 Interventional Results available

Vitamin D and Coronary Calcification Study

NCT00752102
View directory record Official record
Conditions
Chronic Kidney Disease, Vitamin D Deficiency, Coronary Calcification, Disorders of Calcium and Bone Metabolism
Interventions
Calcitriol (Rocaltrol®), Paricalcitol
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
25 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 8, 2017 · Synced Oct 10, 2026, 1:28 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mechanisms of Exercise Resistance in Metabolic Disease

NCT03945435
View directory record Official record
Conditions
Impaired Glucose Tolerance
Interventions
Not listed
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 45 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Oct 10, 2026, 1:28 PM EDT
Not listed Not applicable Interventional

Trial to Assess Continuous Glucose Monitoring in Asian Americans With Type 2 Diabetes

NCT05826678
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Continuous Glucose Monitor, Finger stick glucose monitoring
Device · Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Phase 3 Interventional

Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT)

NCT00594152
View directory record Official record
Conditions
Diabetic Nephropathy, Diabetic Retinopathy
Interventions
CIIIT
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 1995
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 15, 2008 · Synced Oct 10, 2026, 1:28 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Imaging Inflammation in Autoimmune Diabetes

NCT00585936
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Not listed
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 10, 2011 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Not applicable Interventional

Increasing Heart Healthy Behaviors in Youth With Type 1 Diabetes

NCT03531021
View directory record Official record
Conditions
Type1diabetes, Cardiovascular Risk Factor
Interventions
Heart healthy intervention
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
14 Years to 19 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 10, 2026, 1:28 PM EDT
Withdrawn Phase 4 Interventional

L-Arginine and Spironolactone Trial in Dialysis-Dependent ESRD

NCT01855334
View directory record Official record
Conditions
End Stage Renal Disease, Hemodialysis
Interventions
Spironolactone, L-arginine, Placebo
Drug · Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans

NCT01762046
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Glipizide, Metformin, Oral Glucose Tolerance Test
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
1,033 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 10, 2026, 1:28 PM EDT
Completed No phase listed Observational Results available

Cognition in Patients With Hypoglycemia, Without Diabetes

NCT04430582
View directory record Official record
Conditions
Hypoglycemia, Cognition
Interventions
Cognitive Assessment (not diagnostic), ECG
Other · Diagnostic Test
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
22 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Not applicable Interventional

Intensive Care Program for Youth With Diabetes

NCT00961974
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Care Ambassador Intervention, Psychoeducational Intervention
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
8 Years to 16 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 10, 2026, 1:28 PM EDT
Recruiting Not applicable Interventional

Diabetes Body Project 2

NCT07468188
View directory record Official record
Conditions
Eating Disorders, Type 2 Diabetes
Interventions
Body Project Type 2
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 10, 2026, 1:28 PM EDT
Completed Phase 2 Interventional

Effects of Cinnamon Supplementation on Glucose Metabolism in Patients With Pre-diabetes

NCT03219411
View directory record Official record
Conditions
Dysglycemia, Obesity
Interventions
Cinnamon, placebo
Dietary Supplement · Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
20 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Oct 10, 2026, 1:28 PM EDT