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ClinicalTrials.gov public records Last synced Oct 9, 2026, 3:57 PM EDT

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Showing 73–96 of 96 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Prisma Health-Upstate Clear all
Recruiting No phase listed Observational

Near Infrared Spectroscopy (NIRS) as a Method for Measuring Oxidative Capacity of Skeletal Muscle Mitochondria in Breast Cancer and All Gynecological Cancer Patients

NCT06672497
View directory record Official record
Conditions
Breast Cancer, Gynecologic Cancers, Mitochondrial Function
Interventions
Not listed
Lead sponsor
University of South Carolina
Other
Eligibility
20 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Oct 9, 2026, 3:57 PM EDT
Enrolling by invitation Not applicable Interventional

Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair

NCT06874413
View directory record Official record
Conditions
Frailty, Ventral Hernia
Interventions
Prehabilitation, Standard of Care (SOC)
Behavioral · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
65 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 9, 2026, 3:57 PM EDT
Completed Not applicable Interventional

A RCT of CenteringPregnancy on Birth Outcomes

NCT02640638
View directory record Official record
Conditions
Pregnancy, Preterm Birth
Interventions
CenteringPregnancy
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
2,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
Los Angeles, California • Atlanta, Georgia • Clemson, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 9, 2026, 3:57 PM EDT
Completed Not applicable Interventional

Mindfulness Training and Group Counseling Among Prediabetes and Diabetes Patients

NCT04702477
View directory record Official record
Conditions
Stress, Diabetes, Pre-Diabetes, Health Behavior, Quality of Life
Interventions
Mindfulness Based Stress Reduction
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 9, 2026, 3:57 PM EDT
Completed No phase listed Observational

Outpatient Cervical Ripening

NCT04041687
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Oct 9, 2026, 3:57 PM EDT
Completed Not applicable Interventional

Connect for Health Pediatric Weight Management Program

NCT04042493
View directory record Official record
Conditions
Overweight and Obesity, Severe Obesity
Interventions
Connect for Health
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
2 Years to 12 Years
Enrollment
19,304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Denver, Colorado • Boston, Massachusetts • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 9, 2026, 3:57 PM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of Virtual Reality Assisted Guided Imagery (VRAGI) for Pain in Advanced Cancer Patients.

NCT05348174
View directory record Official record
Conditions
Cancer Pain, Oncology, Virtual Reality, Depression, Anxiety
Interventions
Virtual Reality Assisted Guided Imagery (VRAGI)
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Clemson, South Carolina • Columbia, South Carolina • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Oct 9, 2026, 3:57 PM EDT
Completed Not applicable Interventional Results available

Patient-Centered Models of HCV Care for People Who Inject Drugs

NCT02824640
View directory record Official record
Conditions
Hepatitis C, Medication Adherence
Interventions
Patient Navigation, modified Directly Observed Therapy
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 70 Years
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 9, 2026, 3:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Two Different Sperm Processing Methods and Their Effects on Sperm DNA Fragmentation and Embryo Development

NCT06990841
View directory record Official record
Conditions
DNA Damage, DNA Strand Breaks, Sperm DNA Fragmentation
Interventions
sperm separation device
Device
Lead sponsor
Richard Kordus, PhD, HCLD (ABB)
Other
Eligibility
18 Years to 34 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 9, 2026, 3:57 PM EDT
Withdrawn Phase 4 Interventional

VAPorized Administration of Bumetanide for Outpatient Relief in Heart Failure

NCT07375212
View directory record Official record
Conditions
Heart Failure Congestive
Interventions
Bumetanide, intranasal 4mg
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 9, 2026, 3:57 PM EDT
Terminated Phase 1 Interventional Results available

Trial of Famotidine & N-Acetyl Cysteine for Outpatients With COVID-19

NCT04545008
View directory record Official record
Conditions
Covid19
Interventions
Famotidine, N-Acetyl cysteine
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Easley, South Carolina • Greenville, South Carolina • Greer, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 18, 2022 · Synced Oct 9, 2026, 3:57 PM EDT
Completed Not applicable Interventional

Immobilization Versus Observation in Children With Toddler's Fractures: a Prospective Randomized Controlled Trial

NCT01926795
View directory record Official record
Conditions
Tibial Fractures
Interventions
Short leg cast, No Immobilization
Procedure
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
1 Year to 5 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 9, 2026, 3:57 PM EDT
Recruiting Not applicable Interventional

MULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease

NCT06853158
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Music therapy, Health education
Behavioral · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
14 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Cleveland, Ohio • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 9, 2026, 3:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Airway Management Skills Amongst Anesthesia Providers

NCT05055401
View directory record Official record
Conditions
Airway Management
Interventions
Direct Laryngoscopy, Laryngeal Mask Airways, Video Laryngoscopy
Procedure
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
Not listed
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 9, 2026, 3:57 PM EDT
Completed Not applicable Interventional Results available

Pannus Assistance Needed for Obstetric Ultrasound Studies

NCT05764408
View directory record Official record
Conditions
Obesity Complicating Childbirth, Fetal Anomaly
Interventions
traxi® Panniculus Retractor
Device
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
16 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Oct 9, 2026, 3:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Opioid Sparing Pain Management Strategy

NCT04269109
View directory record Official record
Conditions
Cardiac Surgical Procedures
Interventions
Multi-modal Opioid Sparing Pain Management Protocol
Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Oct 9, 2026, 3:57 PM EDT
Recruiting Phase 4 Interventional

Intracervical Vasopressin

NCT07102615
View directory record Official record
Conditions
Retained Products of Conception
Interventions
Intracervical injection of Vasopressin, Intracervical Injection of saline
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 51 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 9, 2026, 3:57 PM EDT
Completed No phase listed Observational

Pelvic Ring Injury

NCT01821339
View directory record Official record
Conditions
Pelvic Ring Injury
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2016 · Synced Oct 9, 2026, 3:57 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Trauma Screening/Referral and Interpersonal Violence Prevention for Women with Substance Use Disorders

NCT06608979
View directory record Official record
Conditions
Substance Use Disorders, Posttraumatic Stress Disorder, Opioid Use Disorder, Violence, Sexual, Violence, Gender-Based, Violence, Domestic
Interventions
Screening/Referral and Prevention
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Oct 9, 2026, 3:57 PM EDT
Not listed No phase listed Observational

Validation of a Salivary miRNA Diagnostic Test for ASD

NCT05418023
View directory record Official record
Conditions
Autism Spectrum Disorder, Developmental Delay
Interventions
Salivary Collection, Adaptive Assessment, Medical and Demographic questionnaire, Autism Assessment, Intellectual Development Assessment
Other
Lead sponsor
Quadrant Biosciences Inc.
Industry
Eligibility
18 Months to 7 Years
Enrollment
6,604 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
16
States / cities
Santa Ana, California • Atlanta, Georgia • Chicago, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 9, 2026, 3:57 PM EDT
Completed No phase listed Observational

Vfib by ECG or Echo During Cardiac Arrest

NCT04906252
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Echocardiography, Electrocardiogram (ECG)
Diagnostic Test
Lead sponsor
Romolo Gaspari
Other
Eligibility
18 Years and older
Enrollment
813 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
Hartford, Connecticut • Lebanon, New Hampshire • Stony Brook, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 9, 2026, 3:57 PM EDT
Terminated Phase 4 Interventional Results available

Amniotic Membrane Allograft Application in the Management of Venous Leg Ulcerations

NCT02929056
View directory record Official record
Conditions
Varicose Ulcer, Venous Insufficiency
Interventions
AmnioExCel dressing and compression therapy, SOC alginate dressing and compression therapy
Biological · Procedure
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Oct 9, 2026, 3:57 PM EDT
Active, not recruiting No phase listed Observational

Dietary Insights and Nutrition Experiences in Adults on GLP-1 Therapy - A Study on Diet Quality Changes in Adults on GLP-1 Therapy

NCT07313384
View directory record Official record
Conditions
Obesity Type 2 Diabetes Mellitus, Obesity (Disorder)
Interventions
GLP-1 Therapy
Drug
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Columbia, South Carolina • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 9, 2026, 3:57 PM EDT
Completed Not applicable Interventional

An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder

NCT06102200
View directory record Official record
Conditions
Standard of Care, Standard of Care + CBT4CBT, Standard of Care + CBT4CBT + RC
Interventions
CBT4CBT, RC, Sandard of care
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 9, 2026, 3:57 PM EDT