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Showing 1105–1128 of 1,607 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

Vagal Nerve Stimulation for Treatment Resistant Major Depression

NCT04990687
Conditions
Major Depressive Disorder
Interventions
gammaCore™
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Labor Induction, Cervical Ripening
Interventions
Transcervical Foley Catheter, Transcervical Foley Catheter with an EASI
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
15 Years to 45 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
4
States / cities
Birmingham, Alabama • Kansas City, Kansas • Greenville, South Carolina
Conditions
Urinary Incontinence
Interventions
Mobile Health Application focused on behavioral treatments to treat urinary incontinence, Practice Facilitation
Behavioral · Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
20 Years and older · Female only
Enrollment
3,214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • Decatur, Georgia
Conditions
Rheumatoid Arthritis
Interventions
Patient Educational Intervention, Patient Control
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Interventions
Transoral Robotic Surgery
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Metastatic Prostate Cancer
Interventions
[68Ga]PSMA-PET/MRI or PET/CT
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Spinal Cord Disorders
Interventions
yogic breathing and meditation
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Methods for Ascertainment of Gout Flares -A Pilot Study

NCT02855437
Conditions
Gout
Interventions
IVR (Phone call), RheumPro (Smartphone application)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers

Reading Fluency and Accommodative Lag

NCT00383175
Conditions
Ocular Accommodation
Interventions
Autorefractor, standard clinical instrument
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
5 Years to 9 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Eutaw, Alabama
Conditions
Chronic Illness, NYHA Class II-IV Heart Failure
Interventions
ADAPT HF
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Multiple Sclerosis (MS)
Interventions
methylprednisolone
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Dallas, Texas
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Molecular-Guided Surgery for Pancreatic and GI Neuroendocrine Cancers

NCT03623984
Conditions
Neuroendocrine Carcinoma of Pancreas, Carcinoid
Interventions
Gallium Dotatate
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Assessment of Bone Augmentation in Post-Extraction Sockets

NCT00641316
Conditions
Unrestorable Dentition, Post-Extraction Sockets
Interventions
AtraumaticTeeth Extraction, Atraumatic Teeth Extraction/Grafted Extraction Sockets
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries

NCT00582998
Conditions
Fracture of Calcaneus, Pilon or Tibial Plateau
Interventions
Standard Wound Dressing, Vacuum Assisted Closure Device
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Overactive Bladder
Interventions
Mirabegron 50 MG, Posterior Tibial Nerve Stimulation (PTNS)
Drug · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Renal Cell Carcinoma, Colorectal Adenocarcinoma, Non-squamous Non-small Cell Lung Cancer, Platinum-refractory Ovarian Carcinoma, Cervical Carcinoma
Interventions
Nintedanib, Bevacizumab
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Phase 4 Interventional Results available

Chronic Hypertension and Pregnancy (CHAP) Project

NCT02299414
Conditions
Hypertension
Interventions
Anti-hypertensive therapy, No anti-hypertensive therapy (unless BP is severe)
Drug · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years and older · Female only
Enrollment
2,408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
72
States / cities
Birmingham, Alabama • Mobile, Alabama • Little Rock, Arkansas + 54 more
Recruiting No phase listed Observational Accepts healthy volunteers

Exosome Cargo From Preeclampsia Patients

NCT04154332
Conditions
Preeclampsia
Interventions
Sample collection
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2031
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Respiratory Syncytial Virus Infections
Interventions
AZM Group, Control Group
Drug · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
3 Days to 2 Years
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
15
States / cities
Birmingham, Alabama • San Francisco, California • New Haven, Connecticut + 12 more
Completed No phase listed Observational Accepts healthy volunteers

RISE FOR HEALTH Study

NCT05365971
Conditions
Lower Urinary Tract Symptoms
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
3,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
9
States / cities
Birmingham, Alabama • San Diego, California • New Haven, Connecticut + 5 more
Conditions
Kidney Diseases
Interventions
Living Donor Navigator Program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
347 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Completed No phase listed Observational Accepts healthy volunteers

Validation of Bladder Health Instrument for Evaluation in Women

NCT04016298
Conditions
Lower Urinary Tract Symptoms
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
1,222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
8
States / cities
Birmingham, Alabama • San Diego, California • New Haven, Connecticut + 5 more
Conditions
Dental Implant, Bone Loss
Interventions
Allograft particles hydrated with rhPDGF, Allograft particles hydrated in a conventional way with saline.
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Breast Cancer
Interventions
Letrozole, Everolimus, TRC105
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama