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ClinicalTrials.gov public records Last synced Nov 5, 2026, 12:09 PM EST

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Showing 1129–1152 of 22,009 matching trials from the local directory fallback.

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Conditions: Genetic Disease
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 1 Month to 100 Years
Enrollment: 20,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2099
U.S. locations: 33
States / cities: Birmingham, Alabama • Huntsville, Alabama • Los Angeles, California + 21 more

Conditions: Healthy Volunteers, Normal Physiology, Pain
Interventions: Attention, Instructions, Placebo instructions, Thermal Pain; Behavioral
Lead sponsor: National Center for Complementary and Integrative Health (NCCIH); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 550 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2027
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Brain Disease
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 2 Years to 110 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2026
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Leukemia, Promyelocytic, Acute, Neurofibroma, Plexiform, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Sarcoma
Interventions: TURALIO(R); Drug
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 3 Years to 35 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2028
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Pulmonary Arterial Hypertension
Interventions: Placebo, Spironolactone; Drug
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2031
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Dystonia, Essential Tremor, Parkinson's Disease
Interventions: Deep Brain Stimulation, Medtronic Activa Tremor Control System; Procedure · Device
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years to 99 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2029
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Congenital Anomaly, Intellectual Disabilities, Rare Disorders
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 4 Weeks to 99 Years
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Drug Abuse, Nicotine Dependence
Interventions: MagPro X100 Magnetic Stimulator, Magnetom Prisma Fit 3T Scanner, Transcranial Rotating Magnetic Stimulator; Device
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Esophageal Cancer, Head and Neck Cancer, Lung Cancer, Precancerous Condition
Interventions: biopsy, immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology; Procedure · Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 21 Years to 90 Years
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Atopic Dermatitis, Eczema
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 2 Years to 100 Years
Enrollment: 530 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2008
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Healthy Volunteers
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 8 Years to 99 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2007
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Breast Neoplasms
Interventions: Bone marrow biopsy, Breast tissue collection, Peripheral blood draw; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Severe Combined Immunodeficiency
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 6 Months to 99 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Chronic Active Epstein-Barr Virus
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 1 Year to 120 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2002
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Echiniococcus, GI Protozoa, Intestinal Worms, Malaria, Strongyloides
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 3 Years and older
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1998
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Major Depressive Episode (MDE), Perimenopause
Interventions: Not listed
Lead sponsor: Van Andel Research Institute; Other
Eligibility: 40 Years to 55 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2031
U.S. locations: 4
States / cities: Grand Rapids, Michigan • Kalamazoo, Michigan • New York, New York

Conditions: Local Disease, Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma
Interventions: Contrast-Enhanced Ultrasound, Lumason; Procedure · Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Immunology
Interventions: Cell-Based Inactivated Influenza Vaccine, Egg-Based Inactivated Influenza Vaccine; Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Hyperparathyroidism
Interventions: Flurpiridaz PET/CT; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Prostate Carcinoma
Interventions: Non-Interventional Study; Other
Lead sponsor: Masonic Cancer Center, University of Minnesota; Other
Eligibility: 18 Years and older · Male only
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Arthroscopic Medial Meniscus Posterior Root Repair
Interventions: Medial unloader valgus knee brace; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 60 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Appetite, Craving, Overweight (BMI > 25)
Interventions: Study Product; Dietary Supplement
Lead sponsor: Nutrition 21, Inc.; Industry
Eligibility: 35 Years to 70 Years
Enrollment: 138 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Biliary Tract Cancer (BTC), Cervical Cancer Metastatic, Endometrial Cancer, Esophageal Squamous Cell Carcinoma (ESCC), Gastric/GEJ, Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer
Interventions: CR-002; Drug
Lead sponsor: Crescent Biopharma, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 219 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Austin, Texas • Dallas, Texas • Fairfax, Virginia

Conditions: Bladder Cancer, Muscle-Invasive Bladder Carcinoma, Muscle-invasive Bladder Urothelial Carcinoma, Urothelial Carcinoma
Interventions: Cisplatin, Enfortumab vedotin, Fluorouracil, Gemcitabine, Mitomycin c, Pembrolizumab, Radiation therapy, Radical cystectomy; Drug · Procedure
Lead sponsor: Fox Chase Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

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Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

Neural and Psychological Mechanisms of Pain Perception

Inflammatory and Infectious Diseases of the Nervous System

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

Spironolactone for Pulmonary Arterial Hypertension

Deep Brain Stimulation Surgery for Movement Disorders

Genome Medical Sequencing for Gene Discovery

Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging

Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers

Studies of Skin Microbes in Healthy People and in People With Skin Conditions

Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers

Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells

Genetic Basis of Immunodeficiency

Genetic Studies of Chronic Active Epstein-Barr Disease

Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection

The Immunobiological Mechanisms of Depression in Perimenopause

The Use of Contrast Enhanced Ultrasound (CEUS) In Post-Surgical Pancreatic Cancer Patients to Evaluate Local Disease Recurrence

Impact of Egg-Based and Cell-Based Vaccine Platforms on Immune Responses to Repeated Influenza Vaccination

Flurpiridaz F-18 PET/CT Imaging for Detecting Parathyroid Adenomas

Evaluating Prostate Cancer Patient Natural Killer Cell Function Across Racial Background and Addressing Functional Disparities With Trispecific Killer Engagers

Medial Unloader Brace After Root Repair

An Open Label Pilot Study Assessing the Impact of Chromium Picolinate Supplementation on Appetite and Cravings in Overweight Individuals

CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

Risk-Enabled Therapy After Initiating EV/Pembro for Bladder Cancer