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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:48 AM EDT

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Showing 97–120 of 397 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Alcon Research Clear all
Terminated Not applicable Interventional

Safety and Effectiveness of the Hydrus Microstent

NCT05198297
View directory record Official record
Conditions
Open Angle Glaucoma, Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma
Interventions
Hydrus Microstent, Ophthalmic surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
45 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
Bentonville, Arkansas • Zephyrhills, Florida • Fraser, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 18, 2026, 2:48 AM EDT
Completed No phase listed Observational

AcrySof Toric Clinical Results

NCT01214863
View directory record Official record
Conditions
Cataracts, Astigmatism
Interventions
T3, T4, T5
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2012 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 3 Interventional

A Study to Evaluate the Clinical Efficacy and Safety of Tobradex® ST Compared to Azasite® in the Treatment of Subjects With Moderate to Severe Chronic Blepharitis

NCT01102244
View directory record Official record
Conditions
Blepharitis
Interventions
Tobradex ST, Azasite
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 11, 2012 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of Difluprednate 0.05% for the Treatment of Anterior Uveitis

NCT01201798
View directory record Official record
Conditions
Endogenous Anterior Uveitis
Interventions
Difluprednate 0.05% ophthalmic emulsion, Prednisolone acetate 1.0% ophthalmic suspension
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
2 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2012 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 2 Interventional

Anecortave Acetate Versus Placebo in AMD Patients Following PDT

NCT00346866
View directory record Official record
Conditions
AMD
Interventions
anecortave acetate
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
1
States / cities
Beachwood, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 5, 2008 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Deposits on Contact Lenses Worn Daily Wear

NCT00725153
View directory record Official record
Conditions
Refractive Error
Interventions
Balafilcon A contact lenses (PureVision), Etafilcon A contact lenses (Acuvue2)
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2012 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Comparison of OPTI-FREE RepleniSH and ReNu Multi-Plus Lens Care Regimens on Corneal Epithelium

NCT00724269
View directory record Official record
Conditions
Contact Lens Wear
Interventions
OPTI-FREE RepleniSH, ReNu MultiPlus MPS
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2012 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 4 Interventional Results available

Low Cylinder Toric

NCT00732030
View directory record Official record
Conditions
Cataracts
Interventions
Toric IOL (SN60T3)
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 7, 2010 · Synced Oct 18, 2026, 2:48 AM EDT
Completed No phase listed Observational

Air Optix Plus HydraGlyde Multifocal Daily/Extended Wear Contact Lenses

NCT05886894
View directory record Official record
Conditions
Refractive Errors
Interventions
Lotrafilcon B multifocal soft contact lenses, Comfilcon A multifocal soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
8
States / cities
San Diego, California • Jacksonville, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Total30 Sphere Contact Lenses

NCT05183022
View directory record Official record
Conditions
Contact Lens Complication, Dry Eye
Interventions
Total30 Sphere Contact Lenses
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 16, 2022 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Comparison Between iLux and LipiFlow in the Treatment of Meibomian Gland Dysfunction (MGD): A 12-month, Multicenter Study

NCT03956225
View directory record Official record
Conditions
Meibomian Gland Dysfunction, Evaporative Dry Eye Disease
Interventions
Systane iLux® Dry Eye System, LipiFlow® Thermal Pulsation System
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
15
States / cities
Long Beach, California • Los Angeles, California • San Diego, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2021 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional

Systane Ultra Versus Maxidex Versus Saline

NCT01775540
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Systane Ultra, Saline solution, Maxidex
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2013 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Clinical Performance Assessment of Two Silicone Hydrogel Daily Disposable Contact Lenses

NCT05725317
View directory record Official record
Conditions
Refractive Errors, Myopia
Interventions
LID220365 contact lens, LID006961 contact lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Maitland, Florida • Orlando, Florida • Franklin Park, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wettability of Contact Lenses With a Multi-Purpose Solution

NCT00713076
View directory record Official record
Conditions
Vision
Interventions
Polyquaternium-preserved Multi-purpose Lens Cleaning Solution 109182
Other
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Daily Disposable Lenses With Multi-Purpose Solution (MPS)

NCT00733291
View directory record Official record
Conditions
Myopia
Interventions
Nelfilcon A contact lens, Etafilcon A contact lens, FID 107027 solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Dec 28, 2011 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 4 Interventional Results available

Presbyopia-Correcting Intraocular Lenses (IOLs)

NCT00963560
View directory record Official record
Conditions
Cataract
Interventions
ReSTOR +3, Crystalens HD, Crystalens AO
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 9, 2011 · Synced Oct 18, 2026, 2:48 AM EDT
Terminated Phase 1 Interventional

Treatment of Diabetic Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg)

NCT00211406
View directory record Official record
Conditions
Diabetic Retinopathy
Interventions
Anecortave Acetate Sterile Suspension (15 mg)
Drug
Lead sponsor
Manhattan Eye, Ear & Throat Hospital
Other
Eligibility
18 Years and older
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2007 · Synced Oct 18, 2026, 2:48 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Cosmetic Contact Lenses Post-Market Clinical Follow-up Study

NCT06517316
View directory record Official record
Conditions
Cosmetic Appearance
Interventions
Nelfilcon A plano cosmetic contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
12 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses

NCT01268306
View directory record Official record
Conditions
Keratitis
Interventions
B+L Biotrue MPS and B+L PureVision
Device
Lead sponsor
Epstein, Arthur B., OD, FAAO
Individual
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 22, 2016 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Two Monthly Contact Lenses

NCT03459131
View directory record Official record
Conditions
Refractive Errors
Interventions
Comfilcon A with Digital Zone Optics™ contact lenses, Comfilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Maitland, Florida
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Clinical Validation of DACP Digital Design

NCT03567005
View directory record Official record
Conditions
Refractive Errors
Interventions
Nelfilcon A digital contact lenses, Nelfilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
5
States / cities
Bloomington, Illinois • Powell, Ohio • Brentwood, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 3 Interventional Results available

TOBRADEX Ophthalmic Suspension Versus Tobramycin 0.3%/Dexamethasone 0.05% Ophthalmic Suspension

NCT00576251
View directory record Official record
Conditions
Ocular Inflammation Associated With Blepharaconjunctivitis
Interventions
Tobramycin 0.3%/Dexamethasone 0.05%, TOBRADEX
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
2 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2010 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Phase 3 Interventional

A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

NCT00051142
View directory record Official record
Conditions
Glaucoma, Open-Angle, Ocular Hypertension
Interventions
Travoprost, Latanoprost
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2008 · Synced Oct 18, 2026, 2:48 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens

NCT04422990
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
14
States / cities
Los Angeles, California • Novato, California • Oakland, California + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2022 · Synced Oct 18, 2026, 2:48 AM EDT