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ClinicalTrials.gov public records Last synced Oct 14, 2026, 3:59 AM EDT

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Showing 97–120 of 778 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Children's Hospital of Philadelphia Clear all
Recruiting Phase 2 Interventional

Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

NCT05029336
View directory record Official record
Conditions
Systemic Lupus Erythematosus, Systemic Sclerosis
Interventions
Depletion of CD3/CD19 in an autologous stem cell transplant
Biological
Lead sponsor
Stephan Grupp MD PhD
Other
Eligibility
8 Years to 25 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional Results available

Investigating the Experience of Living With Down Syndrome and Obstructive Sleep Apnea Syndrome (Stage 1)

NCT04124471
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Open-ended semi-structured interviews
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 14, 2026, 3:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Genetic Variability in Taste Perception

NCT01841710
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Monell Chemical Senses Center
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Malabsorption Blood Test:Toward a Novel Approach to Quantify Steatorrhea

NCT00572975
View directory record Official record
Conditions
Cystic Fibrosis, Pancreatic Insufficiency
Interventions
Pentadecanoic acid (PA) and Triheptadecanoin (THA)
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 30, 2008 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional Results available

The Opening Doors to Early Intervention Study

NCT03625115
View directory record Official record
Conditions
Development Delay, Development, Child
Interventions
Family Navigator (FN)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 29 Months
Enrollment
357 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 14, 2026, 3:59 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Natural History Study of Mitochondrial Myopathy

NCT05250375
View directory record Official record
Conditions
Primary Mitochondrial Disease
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Years to 100 Years
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 14, 2026, 3:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial

NCT04793412
View directory record Official record
Conditions
Asymmetric Hearing Loss, Single-sided Deafness, Unilateral Deafness
Interventions
Cochlear Implant
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
4 Years to 14 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
5
States / cities
Los Angeles, California • Minneapolis, Minnesota • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional

Study for Treatment of Cancer in Children With Ataxia-telangiectasia

NCT00187057
View directory record Official record
Conditions
Ataxia-Telangiectasia
Interventions
vinblastine, vincristine, prednisone, daunorubicin, doxorubicin, methotrexate, cyclophosphamide, L-asparaginase, etoposide, cytarabine, mercaptopurine, dexamethasone, procarbazine, chemotherapy, intrathecal chemotherapy, steroid therapy
Drug · Procedure
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 10 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2013
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 27, 2015 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional

Text4Vax: Text Message Reminders for Pediatric COVID-19 and Influenza Vaccines 2024-25 Season

NCT06603090
View directory record Official record
Conditions
Influenza, COVID-19, Vaccination Hesitancy
Interventions
Text message influenza vaccine reminders, Text message COVID-19 vaccine reminders, Text message influenza and COVID-19 vaccine reminders
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
6 Months to 17 Years
Enrollment
66,147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Itasca, Illinois • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 14, 2026, 3:59 AM EDT
Recruiting No phase listed Observational

Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures

NCT04604418
View directory record Official record
Conditions
Congenital Heart Disease in Children
Interventions
No intervention. It is observational
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 21 Years
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
9
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional Results available

Real-time Effort Driven VENTilator Management

NCT03266016
View directory record Official record
Conditions
Ventilation Therapy; Complications, Diaphragm Disease, Pediatric Respiratory Diseases
Interventions
Computerized Ventilator Protocol, Esophageal Manometry, Respiratory Inductance Plethysmography (RIP), Diaphragm Ultrasound, Maximal Inspiratory Pressure
Other · Diagnostic Test
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
30 Days to 18 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 14, 2026, 3:59 AM EDT
Recruiting Not applicable Interventional

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

NCT06963463
View directory record Official record
Conditions
Sleep Disturbance, Sleep, Depression, Suicide
Interventions
TranS-C, Sleep Feedback
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional

Comprehensive Clinical Decision Support (CDS) for the Primary Care of Premature Infants

NCT01478711
View directory record Official record
Conditions
Prematurity
Interventions
Clinical Decision Support Tool
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
20 Weeks to 35 Weeks
Enrollment
1,517 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 26, 2013 · Synced Oct 14, 2026, 3:59 AM EDT
Not listed No phase listed Observational

Validation of a Salivary miRNA Diagnostic Test for ASD

NCT05418023
View directory record Official record
Conditions
Autism Spectrum Disorder, Developmental Delay
Interventions
Salivary Collection, Adaptive Assessment, Medical and Demographic questionnaire, Autism Assessment, Intellectual Development Assessment
Other
Lead sponsor
Quadrant Biosciences Inc.
Industry
Eligibility
18 Months to 7 Years
Enrollment
6,604 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
16
States / cities
Santa Ana, California • Atlanta, Georgia • Chicago, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 14, 2026, 3:59 AM EDT
Completed No phase listed Observational

LTFU for Gene Transfer Subjects With Hemophilia B

NCT00515710
View directory record Official record
Conditions
Hemophilia B
Interventions
Not listed
Lead sponsor
Spark Therapeutics, Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 15, 2020 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TechStep: Technology-based Stepped Care to Stem Transgender Adolescent Risk Transmission

NCT04000724
View directory record Official record
Conditions
HIV
Interventions
Text Messaging (Text+Step), WebApp (App+Step), Information/No Step
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
15 Years to 24 Years
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional

Improving Primary Care Follow-up for Patients With Pelvic Inflammatory Disease

NCT01299259
View directory record Official record
Conditions
Pelvic Inflammatory Disease
Interventions
Text Message Reminders
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
15 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 28, 2014 · Synced Oct 14, 2026, 3:59 AM EDT
Completed No phase listed Observational

Pharmacokinetic Study of Sub-q and IV Treprostinil in Kids With Pulmonary Arterial Hypertension (PAH)

NCT02318186
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Not listed
Lead sponsor
Jeffrey A. Feinstein
Other
Eligibility
Up to 18 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Oct 14, 2026, 3:59 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy

NCT06783946
View directory record Official record
Conditions
Kidney Stone, Pain, Postoperative, Anxiety Postoperative
Interventions
Meditation
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 14, 2026, 3:59 AM EDT
Completed Not applicable Interventional

Cognitive Remediation Therapy for Adolescents With Anorexia Nervosa

NCT02883413
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
CRT + Teach the Parent, CRT + Contact Control
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 14, 2026, 3:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Urinary Titin Biomarker in DMD

NCT07332013
View directory record Official record
Conditions
Duchenne Muscular Dystrophy (DMD), Becker's Muscular Dystrophy (BMD)
Interventions
Descending stair walk
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 10 Years · Male only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 14, 2026, 3:59 AM EDT
Not yet recruiting Phase 3 Interventional

NICU Antibiotics and Outcomes (NANO) Follow-up Study

NCT05977400
View directory record Official record
Conditions
Premature Birth, Antibiotics, Neurodevelopment
Interventions
Ampicillin, Gentamicin, Placebo
Drug
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 30 Weeks
Enrollment
802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
14
States / cities
San Diego, California • New Haven, Connecticut • Tampa, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2023 · Synced Oct 14, 2026, 3:59 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Obesity and Pediatric Multiple Sclerosis

NCT04593082
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
10 Years to 20 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 14, 2026, 3:59 AM EDT
Recruiting Not applicable Interventional

Motivation for Daily Living Skills

NCT07159308
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD), Motivation
Interventions
Intrinsic Motivation Treatment, Extrinsic Motivation Treatment, Combined Intrinsic and Extrinsic Motivation Treatment
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
16 Years to 25 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 14, 2026, 3:59 AM EDT